Protein Alignment alpha-Man-Ia and mans-3

DIOPT Version :10

• Sequence 1: NP_727408.2
• Gene: alpha-Man-Ia / 31957
• FlyBaseID: FBgn0259170
• Length: 684
• Species: Drosophila melanogaster
• Sequence 2: NP_508877.1
• Gene: mans-3 / 180787
• WormBaseID: WBGene00020197
• Length: 584
• Species: Caenorhabditis elegans
• Alignment Length: 537
• Identity: 195/537 - (36%)
• Similarity: 286/537 - (53%)
• Gaps: 54/537 - (10%)

  Fly   170 LTAATTSSAKS----LENSQ---------GSDTPHSHANTTN-----ADITMGI------ADHNP 210
            :|..:...||.    :||.:         |..|.||...:..     .||...|      |....
 Worm    57 ITICSQGEAKREQPIVENPEIIINEQVIAGQKTKHSKEESAENLKPVHDIDRQIVEDEMDAPETG 121

  Fly   211 GG----IQF-----ERRAHVKQMMEHAWHNYKLYAWGKNELRPLSQRPHSASIFGSYDLGATIVD 266
            ||    ::|     :|:..|.:..:|||..||.||||.:.|:|:|:     |....:|.|.||||
 Worm   122 GGNEKIVKFTGPTNDRQKAVVKAFQHAWIGYKKYAWGHDTLKPVSK-----SYSDWFDTGLTIVD 181

  Fly   267 GLDTLYIMGLEKEYREGRDWIERKFSLDNISAELSVFETNIRFVGGMLTLYAFTGDPLYKEKAQH 331
            ||||..|||||.|..|..:||:...:.:. ...::.||..||.:|||::.:..||..::.||:..
 Worm   182 GLDTAIIMGLEDEATEATEWIQNTLTFEK-DRMVNFFECTIRVLGGMMSAFHLTGKKMFLEKSVD 245

  Fly   332 VADKLLPAFQTPTGIPYALVNTKTGVAKNYGWASGGSSILSEFGTLHLEFAYLSDITGNPLYRER 396
            :.|:||.||::|:.|||:.||.....|.|..|  |..|.|||..|:.||:..||..:||..|.:.
 Worm   246 LGDRLLSAFKSPSPIPYSDVNLLKRTATNPQW--GADSSLSEVTTVQLEYRALSRASGNSTYEDL 308

  Fly   397 VQTIRQVLKEI--EKPKGLYPNFLNPKTGKWGQ-LHMSLGALGDSYYEYLLKAWLQSGQTDEEAR 458
            ...:.:.:.:|  |..:||...|:|..||.:.: ..::.||..||:||||.|.|:|:|:|.:..:
 Worm   309 TFNVFKHIHKIGCETHEGLCGMFINANTGNFKKDSTITFGARSDSFYEYLFKQWIQTGKTIDWLK 373

  Fly   459 EMFDEAMLAILDKMVRTS-PGGLTYVSD-LKFDRLEHKMDHLACFSGGLFALGAATRQNDYTDKY 521
            |.:.:||.|:...:.|.| |..:.::.: |.......|||||.||..|..:.|:   |:.:..|:
 Worm   374 EDYGKAMKAMEKYLYRNSKPNKMFFIGELLSGQTYSPKMDHLVCFIAGTLSQGS---QHGFPRKH 435

  Fly   522 MEVGKGITNTCHESYIRAPTQLGPEAFRFS--EAVEARALRSQEKYYILRPETFESYFVLWRLTH 584
            :::.:.|..|||..|.. ||.||||...|:  ...|...::..:.:.:||||..|::|.|:|.|.
 Worm   436 LDMAEKIGETCHNMYDN-PTGLGPEIAHFNMIPGKEDLYVKPLDAHCLLRPEAIEAWFYLYRFTG 499

  Fly   585 DQKYRDWGWEAVLALEKHCR-TAHGYCGLRNVYQQEPQKDDVQQSFFLAETLKYLYLLFSDD-SV 647
            |:||::|||.|..|:||:.| ...||..:.||.|...:..|..:||.|.||.||||||..|| :|
 Worm   500 DKKYQEWGWSAFQAIEKYARIPTGGYSSISNVKQINVRFRDSMESFLLGETFKYLYLLLGDDQTV 564

  Fly   648 LPLDEWVFNTEAHPLPI 664
            ||||:|||.||.|||||
 Worm   565 LPLDKWVFTTEGHPLPI 581

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Man-Ia	NP_727408.2	LanC_like	216..664	CDD:471159	177/456 (39%)
mans-3	NP_508877.1	Glyco_hydro_47	144..581	CDD:460241	175/448 (39%)