Protein Alignment alpha-Man-Ia and C47E12.3

DIOPT Version :10

• Sequence 1: NP_727408.2
• Gene: alpha-Man-Ia / 31957
• FlyBaseID: FBgn0259170
• Length: 684
• Species: Drosophila melanogaster
• Sequence 2: NP_501802.2
• Gene: C47E12.3 / 177857
• WormBaseID: WBGene00008148
• Length: 568
• Species: Caenorhabditis elegans
• Alignment Length: 545
• Identity: 152/545 - (27%)
• Similarity: 252/545 - (46%)
• Gaps: 108/545 - (19%)

  Fly   173 ATTSSAKSLENSQGSDTPH-------SHANTTNADITMGIADHNPGGIQFERRAHVKQMMEHAWH 230
            :||.|.|:.:|      |.       .:|:.::.|:..|:             |..::|.:..|.
 Worm    15 STTCSLKTTKN------PFLLTKEEIKYASISDVDLQYGL-------------AKTREMFQFGWD 60

  Fly   231 NYKLYAWGKNELRPLSQR--------PHSAS---IFGSYDLGATIVDGLDTLYIMGLEKEYREGR 284
            ||..:|:..:||.|:..|        |.:.:   :.|.|.||  ::|.||:|.:.|...|::...
 Worm    61 NYMEHAFPADELDPIHCRGRGHDHDNPDNINVNDVLGDYSLG--LIDTLDSLVVFGDADEFKRAV 123

  Fly   285 DWIERKFSLDNISAELSVFETNIRFVGGMLTLYAFTGD------PLYKEK--------AQHVADK 335
            :.:.:..|.:. :..:.|||:.||.:||:|..:....|      |.|...        |..:|.:
 Worm   124 NLVIKTVSFEK-NTTVQVFESTIRVMGGLLAAHMIAADKTNRFGPFYMSDYGGELLTLAHDLAGR 187

  Fly   336 LLPAFQ-TPTGIPYALVNTKTGVAKNYGWASGGSSILSEFGTLHLEFAYLSDITGNPLYRERVQT 399
            |||||. |.|||||..:|.:.|:..    .:..|:..|..|:|.|||..||.:.|:..|....:.
 Worm   188 LLPAFDGTATGIPYTRINLQKGILP----GTTNSTCTSGAGSLLLEFGVLSKLLGDDTYERLARR 248

  Fly   400 IRQVLKEI-EKPKGLYPNFLNPKTGKW-GQLHMSLGALGDSYYEYLLKAWLQSGQTDEEAREMFD 462
            :.:.|..: .:..||:.|.::.:||:| |.| ..|||..||:|||:||:::..|  ::...:|::
 Worm   249 VNEKLWNLRNEVTGLHGNLIDIQTGEWLGHL-AGLGAGIDSFYEYMLKSYILFG--NQRDLDMYN 310

  Fly   463 EAMLAILDKMVRTSPGGLTYVSDLKFD-----RLEHK--------MDHL-ACFSGGLFALGAATR 513
            |:...|...|.|    |.:..|.|:.|     .::.:        :|.| |.|:|.|...|
 Worm   311 ESFARITTYMRR----GRSRCSSLEGDIPIYVNVDSRDGSTSNTWIDSLQASFAGVLVLAG---- 367

  Fly   514 QNDYTDKYMEVGKGITNTCHES-YIRAPTQLGPEAFRFSEAVEARALRSQEKYYILRPETFESYF 577
                     ||.:.:   ||.: |.....:.|....||:..::|    ....:|.||||..||.:
 Worm   368 ---------EVDEAV---CHHALYYAIWKKYGVLPERFNWQLQA----PDVSFYPLRPEFVESTY 416

  Fly   578 VLWRLTHDQKYRDWGWEAVLALEKHCRTAHGYCGLRNVYQQEPQKDDVQQSFFLAETLKYLYLLF 642
            :|:..|.:..|:..|.|.:.:||...|...|:..:.:|.  :...:|..:||||:||||||||||
 Worm   417 LLYTATKNPFYQHVGLEILDSLETITRVKCGFATVHDVI--DGSLEDRMESFFLSETLKYLYLLF 479

  Fly   643 SDDSVLPLDEW---VFNTEAHPLPI 664
            ..|..:..::.   :|:||.|..||
 Worm   480 DVDHPINKEQQESVLFSTEGHIFPI 504

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Man-Ia	NP_727408.2	LanC_like	216..664	CDD:471159	141/493 (29%)
C47E12.3	NP_501802.2	Glyco_hydro_47	54..504	CDD:460241	140/485 (29%)