Protein Alignment alpha-Man-Ia and mans-1

DIOPT Version :9

• Sequence 1: NP_727408.2
• Gene: alpha-Man-Ia / 31957
• FlyBaseID: FBgn0259170
• Length: 684
• Species: Drosophila melanogaster
• Sequence 2: NP_492116.1
• Gene: mans-1 / 172510
• WormBaseID: WBGene00008411
• Length: 540
• Species: Caenorhabditis elegans
• Alignment Length: 667
• Identity: 260/667 - (38%)
• Similarity: 380/667 - (56%)
• Gaps: 149/667 - (22%)

  Fly    12 LVICGVVLTIILVCITGITLTNSINISNIVKLREKVASDSAAANGGHQAAQTRAALVEQQYSTLQ 76
            ||:|..|:.::.||||......|                     ||
 Worm     9 LVVCVGVMFLLTVCITAFFFLPS---------------------GG------------------- 33

  Fly    77 QHHLSRSDLNYIQA-ATHPKN--LQRQLQQQQQQQLQQ--QQPNKIVI---EIGLSNDSGPSSAP 133
                  :||.:.:. :.|.::  ::.::::::|.:|::  ::.|.|.|   |||.|:|:
 Worm    34 ------ADLYFREENSVHVRDVLIREEIRRKEQDELRRKAEEANPIPIPKPEIGASDDA------ 86

  Fly   134 ASSTLGSSSTGPRILQAAEALMEGNVDSISLPAAAPLTAATTSSAKSLENSQGSDTPHSHANTTN 198
                                  ||
 Worm    87 ----------------------EG----------------------------------------- 88

  Fly   199 ADITMGIADHNPGGIQFERRAHVKQMMEHAWHNYKLYAWGKNELRPLSQRPHSASIFGSYDLGAT 263
                              ||..||||::.||..|:.||||:|||||.|:..||:||||....|||
 Worm    89 ------------------RRIFVKQMIKFAWDGYRKYAWGENELRPNSRSGHSSSIFGYGKTGAT 135

  Fly   264 IVDGLDTLYIMGLEKEYREGRDWIERKFSLDNISAELSVFETNIRFVGGMLTLYAFTGDPLYKEK 328
            |:|.:||||::||::||:|.||||.......:...:||||||||||.||:|:.:|.|||.::.:|
 Worm   136 IIDAIDTLYLVGLKEEYKEARDWIADFDFKTSAKGDLSVFETNIRFTGGLLSAFALTGDKMFLKK 200

  Fly   329 AQHVADKLLPAFQTPTGIPYALVNTKTGVAKNYGWASGGSSILSEFGTLHLEFAYLSDITGNPLY 393
            |:.||..|||||:||:|||.:|::.:||.:|.|.||| |.:||||:|::.|||.|||::||||::
 Worm   201 AEDVATILLPAFETPSGIPNSLIDAQTGRSKTYSWAS-GKAILSEYGSIQLEFDYLSNLTGNPVF 264

  Fly   394 RERVQTIRQVLKEIEKPKGLYPNFL---NPKTGKWGQLHMSLGALGDSYYEYLLKAWLQSGQTDE 455
            .::...||.||..:|||:||||.::   ||.  :|||...|:||:.||:||||||.|:.:|:.|:
 Worm   265 AQKADKIRDVLTAMEKPEGLYPIYITMDNPP--RWGQHLFSMGAMADSWYEYLLKQWIATGKKDD 327

  Fly   456 EAREMFDEAMLAILDKMV-RTSPGGLTYVSDLKFDRLEHKMDHLACFSGGLFALGAATRQN-DYT 518
            ..:..::||:.|:..:|: ::....|.|.:.:..:|:||..:||||||||:..|.|...:| ..:
 Worm   328 RTKREYEEAIFAMEKRMLFKSEQSNLWYFAKMNGNRMEHSFEHLACFSGGMVVLHAMNEKNKTIS 392

  Fly   519 DKYMEVGKGITNTCHESYIRAPTQLGPEAFRFSEAVEARALRSQEKYYILRPETFESYFVLWRLT 583
            |.||.:||.|.:||||||.|:.|.:|||:|:|:.:|||:..|.|:.|||||||..|::|.|||.|
 Worm   393 DHYMTLGKEIGHTCHESYARSTTGIGPESFQFTSSVEAKTERRQDSYYILRPEVVETWFYLWRAT 457

  Fly   584 HDQKYRDWGWEAVLALEKHCRTAHGYCGLRNVYQQEPQKDDVQQSFFLAETLKYLYLLFSDDSVL 648
            .|:|||.|.|:.|..||::|:...||.|:||||:..|::|||||||..||..|||||:||:|::|
 Worm   458 KDEKYRQWAWDHVQNLEEYCKGTAGYSGIRNVYESSPEQDDVQQSFLFAELFKYLYLIFSEDNIL 522

  Fly   649 PLDEWVFNTEAHPLPIK 665
            |||:|||||||||..|:
 Worm   523 PLDQWVFNTEAHPFRIR 539

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Man-Ia	NP_727408.2	Glyco_hydro_47	224..664	CDD:279825	228/444 (51%)
mans-1	NP_492116.1	Glyco_hydro_47	96..538	CDD:279825	228/444 (51%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	484	1.000	Domainoid score	I195
eggNOG	1	0.900	-	-		E1_KOG2204
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	493	1.000	Inparanoid score	I769
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54359
OrthoDB	1	1.010	-	-		D263455at33208
OrthoFinder	1	1.000	-	-		FOG0001280
OrthoInspector	1	1.000	-	-		oto18468
orthoMCL	1	0.900	-	-		OOG6_100239
Panther	1	1.100	-	-	LDO	PTHR11742
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R728
SonicParanoid	1	1.000	-	-		X635
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	13	12.910