Protein Alignment alpha-Man-Ia and Edem2

DIOPT Version :10

• Sequence 1: NP_727408.2
• Gene: alpha-Man-Ia / 31957
• FlyBaseID: FBgn0259170
• Length: 684
• Species: Drosophila melanogaster
• Sequence 2: XP_314865.4
• Gene: Edem2 / 1275602
• VectorBaseID: AGAMI1_014653
• Length: 806
• Species: Anopheles gambiae
• Alignment Length: 561
• Identity: 167/561 - (29%)
• Similarity: 258/561 - (45%)
• Gaps: 100/561 - (17%)

  Fly   139 GSSSTGPRILQAAEALMEGNVDSISLPAAAPLTAATTSSAKSLENSQGSDTPHSHANTTNADITM 203
            |::|||.|.:...       :..|::..|..|..||.:.|:.:      .|..:| |.:|.:
Mosquito    11 GTASTGHRPIHEL-------LTFIAMLTAVVLGWATLALAEQI------PTVPTH-NMSNKE--- 58

  Fly   204 GIADHNPGGIQFERRAHVKQMMEHAWHNYKLYAWGKNELRPLS----------QRPHSASIFGSY 258
                      :.|.:...::|..||:..|...|:..:||.|||          .|.......|::
Mosquito    59 ----------RNELKEEAREMFYHAYRAYMDNAYPADELMPLSCAGRYRGVTPSRGDLDDTLGNF 113

  Fly   259 DLGATIVDGLDTLYIMGLEKEYREGRDWIERKFSLDNISAELSVFETNIRFVGGMLT-------- 315
            .:  |:||.||||.::|..:|:......:.:....|| ...:||||||||.:||:|:
Mosquito   114 SM--TLVDTLDTLVVLGDLEEFEHAVKLVIKDVKFDN-DIIVSVFETNIRMIGGLLSGHILAEYV 175

  Fly   316 ------LYAFTGDPLYKEKAQHVADKLLPAFQTPTGIPYALVNTKTGVAKNYGWASGGSSILSEF 374
                  :..:.|:.|  |.|:.:..:|||||.|.||||:|.||.|.|: |.........:..:..
Mosquito   176 QKQADVMTWYRGELL--EMAKDLGYRLLPAFNTSTGIPHARVNLKHGM-KVEALRHSRETCTACA 237

  Fly   375 GTLHLEFAYLSDITGNPLYRERVQTIRQVL-KEIEKPKGLYPNFLNPKTGKWGQLHMSLGALGDS 438
            ||:.||||.||.::|.|::..:.......| |...:...|....||..:|.|.:....:||..||
Mosquito   238 GTILLEFAALSRLSGEPIFEVKAHAAMDALWKMRHRSSELMGTVLNVHSGDWIRRESGVGAGIDS 302

  Fly   439 YYEYLLKAWLQSGQTDEEAREMFDEAMLAILDKMVRTSPGGLTYVSDLKFDRLEHK----MDHLA 499
            ||||.||:::..|  ||.....|:....||: |.:...|    .:.|::..|...|    ||.|.
Mosquito   303 YYEYCLKSYILLG--DERYLARFNRHYHAIM-KYISQGP----MLLDVQMHRPHTKTRNFMDALL 360

  Fly   500 CFSGGLFALGA----ATRQNDYTDKYMEVGKGITNTCHESYIRAPTQLGPEAFRFSEAVEARALR 560
            .|..||..|..    |.:.::...:.|::         .::|       ||||.|...|
Mosquito   361 AFWPGLQVLSGDLKPAVQTHEMLYQVMQM---------HTFI-------PEAFTFDFQV------ 403

  Fly   561 SQEKYYILRPETFESYFVLWRLTHDQKYRDWGWEAVLALEKHCRTAHGYCGLRNVYQQEPQKDDV 625
             ....:.||||..||.:.|:|.|.|..|...|.:|:.||:||.|...||..:.:|  :..:.:|.
Mosquito   404 -HWGQHHLRPEFIESTYFLYRATGDHYYLHAGKKALKALQKHARVPCGYAAVNDV--RTGKHEDR 465

  Fly   626 QQSFFLAETLKYLYLLFSD--DSVLPLDEWVFNTEAHPLPI 664
            ..|:.|:||.|||:|||||  |.:|.:::::|.||||.||:
Mosquito   466 MDSYVLSETFKYLFLLFSDPADLILNIEDFIFTTEAHLLPL 506

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Man-Ia	NP_727408.2	LanC_like	216..664	CDD:471159	151/482 (31%)
Edem2	XP_314865.4	None