Protein Alignment alpha-Man-Ia and man1a1

DIOPT Version :10

• Sequence 1: NP_727408.2
• Gene: alpha-Man-Ia / 31957
• FlyBaseID: FBgn0259170
• Length: 684
• Species: Drosophila melanogaster
• Sequence 2: XP_002932159.1
• Gene: man1a1 / 100491314
• XenbaseID: XB-GENE-998953
• Length: 643
• Species: Xenopus tropicalis
• Alignment Length: 561
• Identity: 284/561 - (50%)
• Similarity: 377/561 - (67%)
• Gaps: 44/561 - (7%)

  Fly   127 SGPSSAPASSTLGSSST--GPRILQAAE----ALMEGNVDSISLP----------------AAAP 169
            |.|...|.:..||...|  |.|:.:..|    ||.|.. |:::.|                ....
 Frog    91 SPPPQRPPAGLLGEEETELGGRLARIREEHERALREAK-DTLNRPPDDIKRDIQRDKDRILVQGR 154

  Fly   170 LTAATTSSAKSLENSQGSDTPHSHANTTNADITMGIADHNPGGIQF-ERRAHVKQMMEHAWHNYK 233
            :||.            |...||....      .:|:....|..... ::|..:|:||:.:|.|||
 Frog   155 VTAG------------GKLPPHVFKQ------PVGVVGKEPSDPAVKQKRDTIKEMMKFSWDNYK 201

  Fly   234 LYAWGKNELRPLSQRPHSASIFGSYDLGATIVDGLDTLYIMGLEKEYREGRDWIERKFSLDNISA 298
            .||||.|||:|:.::.||:::||:.. ||||||.||||||||:..|:::.::|:|:.... |::|
 Frog   202 RYAWGMNELKPIQKQGHSSNLFGNIQ-GATIVDALDTLYIMGMMDEFKDAKEWVEKNLEF-NVNA 264

  Fly   299 ELSVFETNIRFVGGMLTLYAFTGDPLYKEKAQHVADKLLPAFQTPTGIPYALVNTKTGVAKNYGW 363
            |:||||.|||||||:|:.|..:|:.:::.||..:.:||||||.||||||:||:|.|:|:.:|:.|
 Frog   265 EVSVFEVNIRFVGGLLSAYYISGEEVFRRKAVELGEKLLPAFNTPTGIPWALLNIKSGIGRNWPW 329

  Fly   364 ASGGSSILSEFGTLHLEFAYLSDITGNPLYRERVQTIRQVLKEIEKPKGLYPNFLNPKTGKWGQL 428
            ||||||||:|||||||||.:|:.::|||::.|:|..||:||..::||:|||||:|||.:|:|||.
 Frog   330 ASGGSSILAEFGTLHLEFMHLTQVSGNPVFAEKVMNIRKVLNRLDKPQGLYPNYLNPSSGQWGQH 394

  Fly   429 HMSLGALGDSYYEYLLKAWLQSGQTDEEAREMFDEAMLAILDKMVRTSPGGLTYVSDLKFDRLEH 493
            |:|:|.||||||||||||||.|.:|||||::|:.|::.|:...::|.|..||||:::.|...|||
 Frog   395 HVSVGGLGDSYYEYLLKAWLMSDKTDEEAKKMYYESVQAVETHLIRKSSSGLTYIAEWKGGLLEH 459

  Fly   494 KMDHLACFSGGLFALGAATRQNDYTDKYMEVGKGITNTCHESYIRAPTQLGPEAFRFSEAVEARA 558
            ||.||.||:||:|||||.....|.|..::|:...|..||||||.|...:||||||||...|||.|
 Frog   460 KMGHLTCFAGGMFALGADGAPEDKTGHHIELAAEIARTCHESYDRTTMKLGPEAFRFDGGVEAIA 524

  Fly   559 LRSQEKYYILRPETFESYFVLWRLTHDQKYRDWGWEAVLALEKHCRTAHGYCGLRNVYQQEPQKD 623
            .|..|||||||||..|:|..:||.|||.|||.||||||.||||:||...||.|:|:||...|..|
 Frog   525 TRQNEKYYILRPEVIETYMYMWRFTHDPKYRQWGWEAVQALEKYCRVEGGYSGVRDVYSAHPNHD 589

  Fly   624 DVQQSFFLAETLKYLYLLFSDDSVLPLDEWVFNTEAHPLPI 664
            ||||||:|||||||||||||||.:|||:.|:||||||||||
 Frog   590 DVQQSFYLAETLKYLYLLFSDDDLLPLEHWIFNTEAHPLPI 630

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Man-Ia	NP_727408.2	LanC_like	216..664	CDD:471159	261/447 (58%)
man1a1	XP_002932159.1	Glyco_hydro_47	192..630	CDD:460241	259/439 (59%)