Protein Alignment alpha-Man-Ia and man1a2

DIOPT Version :10

• Sequence 1: NP_727408.2
• Gene: alpha-Man-Ia / 31957
• FlyBaseID: FBgn0259170
• Length: 684
• Species: Drosophila melanogaster
• Sequence 2: XP_002943491.1
• Gene: man1a2 / 100216029
• XenbaseID: XB-GENE-1010312
• Length: 643
• Species: Xenopus tropicalis
• Alignment Length: 522
• Identity: 278/522 - (53%)
• Similarity: 371/522 - (71%)
• Gaps: 15/522 - (2%)

  Fly   146 RILQAAEALMEGNVDSISLPAAAPLTAATTSSAKSLENSQGSDTPHSH-ANTTNADITMGIADHN 209
            |.|:.|:..::.:.|.|.       ....|..:|..|..:..|.|... |...|..   .|.:.:
 Frog   119 RALEEAKEKLKKSRDEIR-------AEIQTEKSKLAEELKKKDNPPPPLAPVPNLP---EIKNGD 173

  Fly   210 PGGIQF-ERRAHVKQMMEHAWHNYKLYAWGKNELRPLSQRPHSASIFGSYDLGATIVDGLDTLYI 273
            ||.... |:|..:|:||:|||.|||.|.||.|||:|::::.||.:|||:..:||||||.||:|||
 Frog   174 PGDPDIREKRDKIKEMMKHAWDNYKQYGWGHNELKPIARKGHSTNIFGNSQMGATIVDALDSLYI 238

  Fly   274 MGLEKEYREGRDWIERKFSLD-NISAELSVFETNIRFVGGMLTLYAFTGDPLYKEKAQHVADKLL 337
            |||..|:|||::|::.  :|| :::||:||||.||||:||:|..:..:|..::|.||..:|:|||
 Frog   239 MGLLDEFREGQEWVQN--NLDFSVNAEVSVFEVNIRFIGGLLAAFYLSGQEVFKNKAVLLAEKLL 301

  Fly   338 PAFQTPTGIPYALVNTKTGVAKNYGWASGGSSILSEFGTLHLEFAYLSDITGNPLYRERVQTIRQ 402
            |||.||||||:|:||.||||.:|:||||.|||||:|||||||||.:||.:||||:|..:|..||:
 Frog   302 PAFNTPTGIPWAMVNLKTGVGRNWGWASAGSSILAEFGTLHLEFVHLSYLTGNPVYYNKVMHIRK 366

  Fly   403 VLKEIEKPKGLYPNFLNPKTGKWGQLHMSLGALGDSYYEYLLKAWLQSGQTDEEAREMFDEAMLA 467
            :|:::::|.||:||:|||:||:|||.|.|:|.||||:|||||||||.|.::|.|||.|:|.|:.|
 Frog   367 LLQKMDRPNGLFPNYLNPRTGRWGQHHTSVGGLGDSFYEYLLKAWLVSDRSDIEARHMYDSAIEA 431

  Fly   468 ILDKMVRTSPGGLTYVSDLKFDRLEHKMDHLACFSGGLFALGAATRQNDYTDKYMEVGKGITNTC 532
            |...:||.|.||||::.:.|...||.||.||.||:||:.||||.....:....|:::|..|.:||
 Frog   432 IERHLVRKSSGGLTFIGEWKNGHLERKMGHLTCFAGGMLALGADGSPGEKAGHYLQLGAEIAHTC 496

  Fly   533 HESYIRAPTQLGPEAFRFSEAVEARALRSQEKYYILRPETFESYFVLWRLTHDQKYRDWGWEAVL 597
            ||||.|...:||||||:|....||.|:|..|||||||||..|:|:.:||.|||.|||.|||||..
 Frog   497 HESYDRTVLKLGPEAFKFDGGAEAVAVRQNEKYYILRPEVIETYWYMWRFTHDPKYRRWGWEAAQ 561

  Fly   598 ALEKHCRTAHGYCGLRNVYQQEPQKDDVQQSFFLAETLKYLYLLFSDDSVLPLDEWVFNTEAHPL 662
            |::|:||.:.|:.|:::||...|..|||||||||||||||||||||.|.:||||.||||||||||
 Frog   562 AIDKYCRVSGGFSGIKDVYSSSPTYDDVQQSFFLAETLKYLYLLFSSDDLLPLDNWVFNTEAHPL 626

  Fly   663 PI 664
            |:
 Frog   627 PV 628

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Man-Ia	NP_727408.2	LanC_like	216..664	CDD:471159	262/448 (58%)
man1a2	XP_002943491.1	ATP-synt_Fo_b	<111..>153	CDD:473877	8/40 (20%)
		Glyco_hydro_47	189..628	CDD:460241	259/440 (59%)