DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Hk and YPR127W

DIOPT Version :9

Sequence 1:	NP_001259401.1	Gene:	Hk / 31955	FlyBaseID:	FBgn0263220	Length:	887	Species:	Drosophila melanogaster
Sequence 2:	NP_015452.1	Gene:	YPR127W / 856245	SGDID:	S000006331	Length:	345	Species:	Saccharomyces cerevisiae

Alignment Length:	163	Identity:	31/163 - (19%)
Similarity:	72/163 - (44%)	Gaps:	15/163 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly   290 RGLSRKHIIECVRASLQRLQLQYIDIVIIHKAD-PMC------PMEVVRAMSYVIQQGWAMYWGT 347
            || |...:::.|:.|:..:. .||||..:.:.| .:|      |.|...|::.:|.:|.......
Yeast   100 RG-SHDDVVQSVKNSVSAIG-GYIDIFEVARIDTSLCTKGEVYPYESFEALAEMISEGVIGGISL 162

  Fly   348 ARWSQVEIMEAYTNCRQF-NCITPIVEQSEYHMFCREKCELYLPEMYNKIGVGLMAWGPLSMALS 411
            :..::.:|...:.:..:| .|:     :.|..:|..:.....:.:...::|:.::.:.||...|.
Yeast   163 SEVNEEQIRAIHKDWGKFLTCV-----EVELSLFSNDILHNGIAKTCAELGLSIICYSPLGRGLL 222

  Fly   412 DTQNGDKLFLPKGSFKTKSFSWTEDEINRNAAL 444
            ..|......:|:|.|:.....::::.:.:|..|
Yeast   223 TGQLKSNADIPEGDFRKSLKRFSDESLKKNLTL 255

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Hk	NP_001259401.1	Kv_beta	205..531	CDD:213602	31/163 (19%)
Hk	NP_001259401.1	Aldo_ket_red	218..531	CDD:278668	31/163 (19%)
YPR127W	NP_015452.1	AKR_AKR8A1-2	8..329	CDD:381303	31/163 (19%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0667
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810