Protein Alignment Hk and YPL088W

DIOPT Version :9

• Sequence 1: NP_001259401.1
• Gene: Hk / 31955
• FlyBaseID: FBgn0263220
• Length: 887
• Species: Drosophila melanogaster
• Sequence 2: NP_015237.1
• Gene: YPL088W / 856017
• SGDID: S000006009
• Length: 342
• Species: Saccharomyces cerevisiae
• Alignment Length: 378
• Identity: 103/378 - (27%)
• Similarity: 163/378 - (43%)
• Gaps: 96/378 - (25%)

  Fly   208 LGKSGLRISNVGLG-------TWPVFSPGVSDDQAE--AILKLAIESGINLFDISEAH----SET 259
            ||.|||:||.:.:|       .|   :..|.:|:.:  .|:|...:.|:..||.::.:    ||.
Yeast     9 LGNSGLKISPIVIGCMSYGSKKW---ADWVIEDKTQIFKIMKHCYDKGLRTFDTADFYSNGLSER 70

  Fly   260 EIGKILQRAGWKRTAYVITTKVYWSTK-------------------SEERGLSRKHIIECVRASL 305
            .|.:.|:....||...||.||:|:...                   |.:|||||||||..|..|:
Yeast    71 IIKEFLEYYSIKRETVVIMTKIYFPVDETLDLHHNFTLNEFEELDLSNQRGLSRKHIIAGVENSV 135

  Fly   306 QRLQLQYIDIVIIHKADPMCPM-EVVRAMSYVIQQGWAMYWGTARWSQVEIMEAYTNCRQFNCIT 369
            :||. .|||::.||:.|...|| |:::|::.|::.|...|.|.:.....|..|......::....
Yeast   136 KRLG-TYIDLLQIHRLDHETPMKEIMKALNDVVEAGHVRYIGASSMLATEFAELQFTADKYGWFQ 199

  Fly   370 PIVEQSEYHMFCREKCELYLPEMYNKIGVGLMAWGP-----LSMALSDTQNGDKLFLPKGSFKTK 429
            .|..||.|::..||. |..|.....:..:||:.|.|     |:..|:  |:.|:: ....:||:.
Yeast   200 FISSQSYYNLLYRED-ERELIPFAKRHNIGLLPWSPNARGMLTRPLN--QSTDRI-KSDPTFKSL 260

  Fly   430 SFSWTEDE----INRNAALSPQGSWGKDRIDEGRRHCDRLRDLAALAEKLGCSPTQLSIAWSLKH 490
            .....|:|    |||...:|      ||:                     ..|...|||||.| |
Yeast   261 HLDNLEEEQKEIINRVEKVS------KDK---------------------KVSMAMLSIAWVL-H 297

  Fly   491 E---PVQCLLLGATSAEQLHQSLQSLQLLPRLSSSVMLELERI--LENKPVRP 538
            :   |:    :|..:..::.:::.:||        |.|..|.|  || :|.:|
Yeast   298 KGCHPI----VGLNTTARVDEAIAALQ--------VTLTEEEIKYLE-EPYKP 337

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hk	NP_001259401.1	Kv_beta	205..531	CDD:213602	99/369 (27%)
		Aldo_ket_red	218..531	CDD:278668	92/359 (26%)
YPL088W	NP_015237.1	AKR_EcYajO-like	5..332	CDD:381305	99/370 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	75	1.000	Domainoid score	I2137
eggNOG	1	0.900	-	-		E1_COG0667
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0.985475	Normalized mean entropy	S2698
OMA	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000530
OrthoInspector	1	1.000	-	-		oto100104
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R634
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	8	7.750