Protein Alignment Hk and AAD4

DIOPT Version :9

• Sequence 1: NP_001259401.1
• Gene: Hk / 31955
• FlyBaseID: FBgn0263220
• Length: 887
• Species: Drosophila melanogaster
• Sequence 2: NP_010038.1
• Gene: AAD4 / 851354
• SGDID: S000002402
• Length: 329
• Species: Saccharomyces cerevisiae
• Alignment Length: 334
• Identity: 82/334 - (24%)
• Similarity: 140/334 - (41%)
• Gaps: 74/334 - (22%)

  Fly   230 VSDDQAEAILKLAIESGINLFDISEAH----SETEIGKILQRAGWK-----RTAYVITTKVYWST 285
            ::.:||..:|....|:|.|..|.:.::    ||..||:      |.     |...||.||.....
Yeast     4 MNKEQAFELLDAFYEAGGNCIDTANSYQNEESEIWIGE------WMKSRKLRDQIVIATKFTGDY 62

  Fly   286 KSEERGLSR--------KHIIE-CVRASLQRLQLQYIDIVIIHKADPMCPM-EVVRAMSYVIQQG 340
            |..|.|..:        ||.:. .||.||::||..:|||:.:|..|.|..: ||:.::..::|||
Yeast    63 KKYEVGGGKSANYCGNHKHSLHVSVRDSLRKLQTDWIDILYVHWWDYMSSIEEVMDSLHILVQQG 127

  Fly   341 WAMYWG---TARWSQVEIMEAYTNCRQFNCITPI-VEQSEYHMFCREKCELYLPEMYNKIGVGLM 401
            ..:|.|   |..|    ::.|.......:..||. :.|.::::..|:.....:| |....|:.|.
Yeast   128 KVLYLGVSDTPAW----VVSAANYYATSHGKTPFSIYQGKWNVLNRDFERDIIP-MARHFGMALA 187

  Fly   402 AWGPL-------SMALSD-TQNGDKLFLPKGSFKTKSFSWTEDEINRNAALSPQGSWGKDRIDEG 458
            .|..:       ..|:.: .:||:.|....|:.|.     |:.|:               :|.|.
Yeast   188 PWDVMGGGRFQSKKAMEERKKNGEGLRTVSGTSKQ-----TDKEV---------------KISEA 232

  Fly   459 RRHCDRLRDLAALAEKLGC-SPTQLSIAWSLKHEPVQCLLLGATSAEQLHQSLQSLQLLPRLSSS 522
                     ||.:||:.|. |.|.::||:..........|:|....|.|.|::::|.:  :|:..
Yeast   233 ---------LAKVAEEHGTESVTAIAIAYVRSKAKNVFPLVGGRKIEHLKQNIEALSI--KLTPE 286

  Fly   523 VMLELERIL 531
            .:..||.|:
Yeast   287 QIEYLESII 295

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hk	NP_001259401.1	Kv_beta	205..531	CDD:213602	81/332 (24%)
		Aldo_ket_red	218..531	CDD:278668	81/332 (24%)
AAD4	NP_010038.1	AKR_AKR9A3_9B1-4	1..292	CDD:381373	79/329 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157345906
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0667
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.740