Protein Alignment Hk and kcnab2a

DIOPT Version :9

• Sequence 1: NP_001259401.1
• Gene: Hk / 31955
• FlyBaseID: FBgn0263220
• Length: 887
• Species: Drosophila melanogaster
• Sequence 2: XP_021335580.1
• Gene: kcnab2a / 797337
• ZFINID: ZDB-GENE-140515-2
• Length: 430
• Species: Danio rerio
• Alignment Length: 431
• Identity: 183/431 - (42%)
• Similarity: 273/431 - (63%)
• Gaps: 47/431 - (10%)

  Fly   130 GAMGVIPSTNDSNNNN-----------------NNNNNVDNTSDESNPVTIYRCRAP--IASLDC 175
            ||.||..|::.|:...                 :::..::....:::...:.|.|..  .|.:..
Zfish    14 GASGVRKSSSSSSGGKMLSMSYSESIRSGISRYHSDQGLNQPPRQTDQAELQRLREQRVAAQIKN 78

  Fly   176 MEEFSRSISLGSNPALPLRHGSTPTPGLRYKNLGKSGLRISNVGLGTWPVFSPGVSDDQAEAILK 240
            ||:|.:...|.....:..:      .|::|:||||||||:|.:|||||..|...::|:.||.::.
Zfish    79 MEDFLKMNGLALEECVSYQ------TGMKYRNLGKSGLRVSCLGLGTWVTFGGQITDEMAEQLMT 137

  Fly   241 LAIESGINLFDISEAH----SETEIGKILQRAGWKRTAYVITTKVYWSTKSE-ERGLSRKHIIEC 300
            ||.|:||||||.:|.:    :|..:|.::::.||:|::.|||||::|..|:| |||||||||||.
Zfish   138 LAYENGINLFDTAEVYAAGKAEVVLGNVIKKKGWRRSSLVITTKIFWGGKAETERGLSRKHIIEG 202

  Fly   301 VRASLQRLQLQYIDIVIIHKADPMCPM-EVVRAMSYVIQQGWAMYWGTARWSQVEIMEAYTNCRQ 364
            ::|||:||||:|:|:|..::.||..|| |.||||::||.||.||||||:|||.:||||||:..||
Zfish   203 LKASLERLQLEYVDVVFANRPDPNTPMEETVRAMTHVINQGMAMYWGTSRWSPMEIMEAYSVARQ 267

  Fly   365 FNCITPIVEQSEYHMFCREKCELYLPEMYNKIGVGLMAWGPLSMALSDTQNGDKLFLPKGSFKTK 429
            ||.|.||.||||||||.|||.|:.|||:::|||||.|.|.||:..:...:. |....|......|
Zfish   268 FNQIPPICEQSEYHMFQREKVEVQLPELFHKIGVGAMTWSPLACGIISGKY-DSGVPPYSRASLK 331

  Fly   430 SFSWTEDEINRNAALSPQGSWGKDRIDEGRRHCDRLRDLAALAEKLGCSPTQLSIAWSLKHEPVQ 494
            .:.|.:|:|     ||          :||||...:|::|.|:||:|||:..||:|||.|::|.|.
Zfish   332 GYQWLKDKI-----LS----------EEGRRQQAKLKELQAIAERLGCTLPQLAIAWCLRNEGVS 381

  Fly   495 CLLLGATSAEQLHQSLQSLQLLPRLSSSVMLELERILENKP 535
            .:||||::.:||.:::.::|:||:||||::.|::.||.|||
Zfish   382 SVLLGASNTDQLMENIGAIQVLPKLSSSIVHEVDSILGNKP 422

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hk	NP_001259401.1	Kv_beta	205..531	CDD:213602	164/331 (50%)
		Aldo_ket_red	218..531	CDD:278668	154/318 (48%)
kcnab2a	XP_021335580.1	Kv_beta	102..418	CDD:213602	164/331 (50%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	300	1.000	Domainoid score	I1392
eggNOG	1	0.900	-	-		E1_COG0667
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000530
OrthoInspector	1	1.000	-	-		otm25505
orthoMCL	1	0.900	-	-		OOG6_100387
Panther	1	1.100	-	-	O	PTHR43150
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R634
SonicParanoid	1	1.000	-	-		X715
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	10	9.800