Protein Alignment Hk and kcnab3

DIOPT Version :10

• Sequence 1: NP_001259401.1
• Gene: Hk / 31955
• FlyBaseID: FBgn0263220
• Length: 887
• Species: Drosophila melanogaster
• Sequence 2: NP_001072370.1
• Gene: kcnab3 / 779823
• XenbaseID: XB-GENE-996883
• Length: 401
• Species: Xenopus tropicalis
• Alignment Length: 398
• Identity: 175/398 - (43%)
• Similarity: 259/398 - (65%)
• Gaps: 48/398 - (12%)

  Fly   155 SDESNPVTIYRCRAPIASLDCMEEFSRSISLGS---NPALP-----LRHGSTPTPGLRYKNLGKS 211
            |...|.||:.:.:            .|:..:|:   :..||     ||..:....|::|:|||||
 Frog    27 SGGQNGVTVAQTK------------QRTPPMGAKNQSQVLPLLSHILRESTVKATGMKYRNLGKS 79

  Fly   212 GLRISNVGLGTWPVFSPGVSDDQAEAILKLAIESGINLFDISEAH----SETEIGKILQRAGWKR 272
            |||:|.:|||||..|...:||:.||.::.:|.|.||||||.:|.:    :|..:||||::..|:|
 Frog    80 GLRVSCLGLGTWVTFGSQISDEVAENLMTVAYEHGINLFDTAEVYAAGRAERTLGKILKKKEWRR 144

  Fly   273 TAYVITTKVYWSTKSE-ERGLSRKHIIECVRASLQRLQLQYIDIVIIHKADPMCPM-EVVRAMSY 335
            ::||:|||:||..::| |||||||||||.:|.||:||||.|:|||..::.||..|| |:||||::
 Frog   145 SSYVVTTKIYWGGQAETERGLSRKHIIEGLRGSLERLQLDYVDIVFANRMDPNSPMEEIVRAMTF 209

  Fly   336 VIQQGWAMYWGTARWSQVEIMEAYTNCRQFNCITPIVEQSEYHMFCREKCELYLPEMYNKIGVGL 400
            ||.||.||||||:|||.:||||||:..||||.|.|:.||:|||:|.|||.|.:|||:|:|||||.
 Frog   210 VINQGMAMYWGTSRWSAMEIMEAYSVARQFNLIPPVCEQAEYHLFQREKVETHLPELYHKIGVGS 274

  Fly   401 MAWGPLSMALSDTQNGDKLFLP---KGSFKTKSFSWTEDEINRNAALSPQGSWGKDRIDEGRRHC 462
            |.|.||:..|...:..|.  :|   :.||  |.:.|.:::     |:|          |||::..
 Frog   275 MTWSPLACGLITGKYADS--VPEKSRASF--KGYHWLKEK-----AIS----------DEGKKQH 320

  Fly   463 DRLRDLAALAEKLGCSPTQLSIAWSLKHEPVQCLLLGATSAEQLHQSLQSLQLLPRLSSSVMLEL 527
            .::::|..:|::|.|:..||:|||.|:.|.|..:|||.:|::||.::|.::|:||.|:..::.|:
 Frog   321 SKVKELHPIADRLNCTVAQLAIAWCLRSEGVSSVLLGVSSSDQLLENLGAIQVLPHLTPQLVTEI 385

  Fly   528 ERILENKP 535
            ::||.|||
 Frog   386 DQILGNKP 393

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hk	NP_001259401.1	AKR_AKR6B1	203..535	CDD:381368	162/340 (48%)
kcnab3	NP_001072370.1	AKR_SF	69..393	CDD:444925	163/342 (48%)