Protein Alignment Hk and Akr1b10

DIOPT Version :10

• Sequence 1: NP_001259401.1
• Gene: Hk / 31955
• FlyBaseID: FBgn0263220
• Length: 887
• Species: Drosophila melanogaster
• Sequence 2: NP_765986.3
• Gene: Akr1b10 / 67861
• MGIID: 1915111
• Length: 316
• Species: Mus musculus
• Alignment Length: 307
• Identity: 73/307 - (23%)
• Similarity: 120/307 - (39%)
• Gaps: 72/307 - (23%)

  Fly   211 SGLRISNVGLGTWPVFSPGVSDDQAEAILKLAIESGINLFDISEAH-SETEIGKI----LQRAGW 270
            :|.::..||||||.  ||.....:|   :|:||::|....|.:..: :|:|:|:.    :|....
Mouse     9 TGAKMPIVGLGTWK--SPPAKVREA---VKVAIDAGYRHIDCAYVYQNESEVGEAIQEKIQEKAV 68

  Fly   271 KRTAYVITTKVYWSTKSEERGLSRKHIIECVRASLQRLQLQYIDIVIIH------KADPMCP--- 326
            ||....|.:|: ||| ..|:.|.:|    ..:.:|..|:|.|:|:.:||      ..:...|
Mouse    69 KREDLFIVSKL-WST-FFEKSLVKK----AFQNTLSDLKLDYLDLYLIHWPQGFQSGNVFLPTDD 127

  Fly   327 -----------MEVVRAMSYVIQQGWAMYWGTARWSQVEIMEAYTN---------CRQFNCITPI 371
                       ::...||..::.||.....|.:.::..:| |...|         ..|..| .|.
Mouse   128 KGSILSSKYTFLDAWEAMEELVDQGLVKALGVSNFNHFQI-ERLLNKPGLKHKPVTNQVEC-HPY 190

  Fly   372 VEQSEYHMFCREKCELYLPEMYNKIGVGLMAWGPL-SMALSDTQNGDKLFLPKGSFK-------- 427
            :.|.:...:|..|            |:.:.|:.|| |......:..|.|.|.....|
Mouse   191 LTQEKLIQYCHSK------------GITITAYSPLGSPDRPSAKPEDPLLLEIPKIKEIAAKHKR 243

  Fly   428 TKSFSWTEDEINRNAALSPQGSWGKDRIDEGRRHCD---RLRDLAAL 471
            |.:.......|.||..:.|: |....||.|..:..|   ...|:||:
Mouse   244 TAAQVLIRFHIERNVVVIPK-SVTPSRIQENIQVFDFQLSEEDMAAI 289

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hk	NP_001259401.1	AKR_AKR6B1	203..535	CDD:381368	73/307 (24%)
Akr1b10	NP_765986.3	AKR_AKR1B1-19	10..316	CDD:381333	73/306 (24%)