Protein Alignment Hk and Kcnab3

DIOPT Version :10

• Sequence 1: NP_001259401.1
• Gene: Hk / 31955
• FlyBaseID: FBgn0263220
• Length: 887
• Species: Drosophila melanogaster
• Sequence 2: NP_113840.1
• Gene: Kcnab3 / 58981
• RGDID: 61830
• Length: 404
• Species: Rattus norvegicus
• Alignment Length: 353
• Identity: 164/353 - (46%)
• Similarity: 238/353 - (67%)
• Gaps: 24/353 - (6%)

  Fly   189 PALPLRHGSTPTPGLRYKNLGKSGLRISNVGLGTWPVFSPGVSDDQAEAILKLAIESGINLFDIS 253
            ||..||..:....|::|:||||||||:|.:|||||..|...:||:.||.:|.:|.|.|:||||.:
  Rat    64 PAGALRESTGRGTGMKYRNLGKSGLRVSCLGLGTWVTFGSQISDETAEDLLTVAYEHGVNLFDTA 128

  Fly   254 EAH----SETEIGKILQRAGWKRTAYVITTKVYWSTKSE-ERGLSRKHIIECVRASLQRLQLQYI 313
            |.:    :|..:|.||:..||:|::||||||::|..::| |||||||||||.::.||.||||:|:
  Rat   129 EVYAAGKAERTLGNILKSKGWRRSSYVITTKIFWGGQAETERGLSRKHIIEGLQGSLDRLQLEYV 193

  Fly   314 DIVIIHKADPMCPM-EVVRAMSYVIQQGWAMYWGTARWSQVEIMEAYTNCRQFNCITPIVEQSEY 377
            |||..:::||..|| |:||||:|||.||.|:||||:|||..||||||:..||||.|.|:.||:|.
  Rat   194 DIVFANRSDPSSPMEEIVRAMTYVINQGLALYWGTSRWSAAEIMEAYSMARQFNLIPPVCEQAEN 258

  Fly   378 HMFCREKCELYLPEMYNKIGVGLMAWGPLSMALSDTQNGDKLFLPKGSFKT-KSFSWTEDEINRN 441
            |.|.|||.|:.|||:|:|||||.:.|.||:.:|..::...:  :|.....| |.:.|.::::
  Rat   259 HFFQREKVEMQLPELYHKIGVGSVTWSPLACSLITSKYDGQ--VPDACKATVKGYQWLKEKV--- 318

  Fly   442 AALSPQGSWGKDRIDEGRRHCDRLRDLAALAEKLGCSPTQLSIAWSLKHEPVQCLLLGATSAEQL 506
                        :.::|::...|:.||..:|.:|||:..||:|||.|:.|.|..:|||.:|||||
  Rat   319 ------------QSEDGKKQQARVTDLLPIAHQLGCTVAQLAIAWCLRSEGVSSVLLGVSSAEQL 371

  Fly   507 HQSLQSLQLLPRLSSSVMLELERILENK 534
            .:.|.|||:|.:|:...::|::.:|.||
  Rat   372 MEHLGSLQVLGQLTPQTVMEIDALLGNK 399

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hk	NP_001259401.1	AKR_AKR6B1	203..535	CDD:381368	159/339 (47%)
Kcnab3	NP_113840.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..78		4/13 (31%)
		AKR_KCAB3B_AKR6A9-like	76..400	CDD:381386	160/341 (47%)