Protein Alignment Hk and kcnab2b

DIOPT Version :10

• Sequence 1: NP_001259401.1
• Gene: Hk / 31955
• FlyBaseID: FBgn0263220
• Length: 887
• Species: Drosophila melanogaster
• Sequence 2: XP_005162233.1
• Gene: kcnab2b / 565014
• ZFINID: ZDB-GENE-080219-36
• Length: 469
• Species: Danio rerio
• Alignment Length: 429
• Identity: 188/429 - (43%)
• Similarity: 265/429 - (61%)
• Gaps: 69/429 - (16%)

  Fly   128 GNGAMGVIPSTNDSNNNNNNNNNVDNTSDESNPVTIYRCRAPIASLDCMEEFSRSISLGSNPALP 192
            |.|.||.|.|..:                         .|| .|.|..:|:|.||..:....::.
Zfish    81 GGGEMGEIRSLRE-------------------------VRA-AAQLKNLEDFLRSNGVSLQESIS 119

  Fly   193 LRHGSTPTPGLRYKNLGKSGLRISNVGLGTWPVFSPGVSDDQAEAILKLAIESGINLFDISEAH- 256
            .:      .|:||:||||||||:|.:|||||..|...::|:.||.::.||.|:||||||.:|.:
Zfish   120 FQ------TGMRYRNLGKSGLRVSCLGLGTWVTFGGQITDEIAEQLMTLAYENGINLFDTAEVYA 178

  Fly   257 ---SETEIGKILQRAGWKRTAYVITTKVYWSTKSE-ERGLSRKHIIECVRASLQRLQLQYIDIVI 317
               :|..:|.|:::.||:|::.|||||:||..|:| |||||||||||.:||||:||||:|:|:|.
Zfish   179 AGKAEMVLGSIIKKKGWRRSSLVITTKIYWGGKAETERGLSRKHIIEGLRASLERLQLEYVDVVF 243

  Fly   318 IHKADPMCPM----------------EVVRAMSYVIQQGWAMYWGTARWSQVEIMEAYTNCRQFN 366
            .::.||..||                |.||||::||.||.||||||:|||.:||||||:..||||
Zfish   244 ANRPDPNTPMEGDPFNTSKSRTFIIEETVRAMTHVINQGMAMYWGTSRWSSMEIMEAYSVARQFN 308

  Fly   367 CITPIVEQSEYHMFCREKCELYLPEMYNKIGVGLMAWGPLSMALSDTQNGDKLFLPKGSFKTKSF 431
            .|.|:.||:|||||.|||.|:.|||:::|||||.|.|.||:..:...:. |....|......|.:
Zfish   309 LIPPVCEQAEYHMFQREKVEVQLPELFHKIGVGAMTWSPLACGIISGKY-DSGVPPCSRASLKGY 372

  Fly   432 SWTEDEINRNAALSPQGSWGKDRIDEGRRHCDRLRDLAALAEKLGCSPTQLSIAWSLKHEPVQCL 496
            .|.:|:|     ||          :||||...:|::|.|:||:|||:..||:|||.|::|.|.|:
Zfish   373 QWMKDKI-----LS----------EEGRRQQAKLKELQAIAERLGCTLPQLAIAWCLRNEGVSCV 422

  Fly   497 LLGATSAEQLHQSLQSLQLLPRLSSSVMLELERILENKP 535
            ||||:|.:||.:::.::|:||:||||::.|::.||.|||
Zfish   423 LLGASSTDQLMENIGAIQVLPKLSSSIIHEVDSILGNKP 461

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hk	NP_001259401.1	AKR_AKR6B1	203..535	CDD:381368	171/352 (49%)
kcnab2b	XP_005162233.1	Aldo_ket_red_shaker	125..449	CDD:381367	166/339 (49%)