Protein Alignment Hk and kcnab2b

DIOPT Version :9

• Sequence 1: NP_001259401.1
• Gene: Hk / 31955
• FlyBaseID: FBgn0263220
• Length: 887
• Species: Drosophila melanogaster
• Sequence 2: XP_005162233.1
• Gene: kcnab2b / 565014
• ZFINID: ZDB-GENE-080219-36
• Length: 469
• Species: Danio rerio
• Alignment Length: 429
• Identity: 188/429 - (43%)
• Similarity: 265/429 - (61%)
• Gaps: 69/429 - (16%)

  Fly   128 GNGAMGVIPSTNDSNNNNNNNNNVDNTSDESNPVTIYRCRAPIASLDCMEEFSRSISLGSNPALP 192
            |.|.||.|.|..:                         .|| .|.|..:|:|.||..:....::.
Zfish    81 GGGEMGEIRSLRE-------------------------VRA-AAQLKNLEDFLRSNGVSLQESIS 119

  Fly   193 LRHGSTPTPGLRYKNLGKSGLRISNVGLGTWPVFSPGVSDDQAEAILKLAIESGINLFDISEAH- 256
            .:      .|:||:||||||||:|.:|||||..|...::|:.||.::.||.|:||||||.:|.:
Zfish   120 FQ------TGMRYRNLGKSGLRVSCLGLGTWVTFGGQITDEIAEQLMTLAYENGINLFDTAEVYA 178

  Fly   257 ---SETEIGKILQRAGWKRTAYVITTKVYWSTKSE-ERGLSRKHIIECVRASLQRLQLQYIDIVI 317
               :|..:|.|:::.||:|::.|||||:||..|:| |||||||||||.:||||:||||:|:|:|.
Zfish   179 AGKAEMVLGSIIKKKGWRRSSLVITTKIYWGGKAETERGLSRKHIIEGLRASLERLQLEYVDVVF 243

  Fly   318 IHKADPMCPM----------------EVVRAMSYVIQQGWAMYWGTARWSQVEIMEAYTNCRQFN 366
            .::.||..||                |.||||::||.||.||||||:|||.:||||||:..||||
Zfish   244 ANRPDPNTPMEGDPFNTSKSRTFIIEETVRAMTHVINQGMAMYWGTSRWSSMEIMEAYSVARQFN 308

  Fly   367 CITPIVEQSEYHMFCREKCELYLPEMYNKIGVGLMAWGPLSMALSDTQNGDKLFLPKGSFKTKSF 431
            .|.|:.||:|||||.|||.|:.|||:::|||||.|.|.||:..:...:. |....|......|.:
Zfish   309 LIPPVCEQAEYHMFQREKVEVQLPELFHKIGVGAMTWSPLACGIISGKY-DSGVPPCSRASLKGY 372

  Fly   432 SWTEDEINRNAALSPQGSWGKDRIDEGRRHCDRLRDLAALAEKLGCSPTQLSIAWSLKHEPVQCL 496
            .|.:|:|     ||          :||||...:|::|.|:||:|||:..||:|||.|::|.|.|:
Zfish   373 QWMKDKI-----LS----------EEGRRQQAKLKELQAIAERLGCTLPQLAIAWCLRNEGVSCV 422

  Fly   497 LLGATSAEQLHQSLQSLQLLPRLSSSVMLELERILENKP 535
            ||||:|.:||.:::.::|:||:||||::.|::.||.|||
Zfish   423 LLGASSTDQLMENIGAIQVLPKLSSSIIHEVDSILGNKP 461

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hk	NP_001259401.1	Kv_beta	205..531	CDD:213602	167/346 (48%)
		Aldo_ket_red	218..531	CDD:278668	157/333 (47%)
kcnab2b	XP_005162233.1	Kv_beta	126..457	CDD:213602	167/346 (48%)
		Aldo_ket_red	126..456	CDD:119408	167/345 (48%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	300	1.000	Domainoid score	I1392
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000530
OrthoInspector	1	1.000	-	-		otm25505
orthoMCL	1	0.900	-	-		OOG6_100387
Panther	1	1.100	-	-	O	PTHR43150
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R634
SonicParanoid	1	1.000	-	-		X715
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	9	8.940