Protein Alignment Hk and kcnab1

DIOPT Version :9

• Sequence 1: NP_001259401.1
• Gene: Hk / 31955
• FlyBaseID: FBgn0263220
• Length: 887
• Species: Drosophila melanogaster
• Sequence 2: XP_012818504.1
• Gene: kcnab1 / 549740
• XenbaseID: XB-GENE-950688
• Length: 429
• Species: Xenopus tropicalis
• Alignment Length: 354
• Identity: 169/354 - (47%)
• Similarity: 245/354 - (69%)
• Gaps: 28/354 - (7%)

  Fly   191 LPLRHGSTPTPGLRYKNLGKSGLRISNVGLGTWPVFSPGVSDDQAEAILKLAIESGINLFDISEA 255
            |...|......|:.|:||||||||:|.:|||||..|...:||:.||.::.:|.|:|:||||.:|.
 Frog    87 LSYEHTVACRTGMPYRNLGKSGLRVSCLGLGTWVTFGGQISDEVAEQLMTIAYENGVNLFDTAEV 151

  Fly   256 H----SETEIGKILQRAGWKRTAYVITTKVYWSTKSE-ERGLSRKHIIECVRASLQRLQLQYIDI 315
            :    :|..:|.|:::..|:|::.|||||:||..|:| |||||||||||.::|||||:||:|:|:
 Frog   152 YAAGKAEIILGNIIRKKNWRRSSLVITTKLYWGGKAETERGLSRKHIIEGLKASLQRMQLEYVDV 216

  Fly   316 VIIHKADPMCPM-EVVRAMSYVIQQGWAMYWGTARWSQVEIMEAYTNCRQFNCITPIVEQSEYHM 379
            |..::.|...|| |:||||||||.||.||||||:|||.:||||||:..||||.|.|:.||:|||:
 Frog   217 VFANRPDNNTPMEEIVRAMSYVINQGMAMYWGTSRWSAMEIMEAYSVARQFNMIPPVCEQAEYHL 281

  Fly   380 FCREKCELYLPEMYNKIGVGLMAWGPLSMAL--SDTQNGDKLFLPKGS-FKTKSFSWTEDEINRN 441
            |.|||.|:.|||:|:|||||.|.|.||:..:  ...:||    :|:.: ...|.:.|.:|:|
 Frog   282 FQREKVEVQLPELYHKIGVGAMTWSPLACGIISGKYENG----VPESTRASLKCYQWLKDKI--- 339

  Fly   442 AALSPQGSWGKDRIDEGRRHCDRLRDLAALAEKLGCSPTQLSIAWSLKHEPVQCLLLGATSAEQL 506
              ||          :|||:...:||||..:||:|||:..||::||.|::|.|..:|||:::.|||
 Frog   340 --LS----------EEGRKQRTKLRDLMPIAERLGCTLPQLAVAWCLRNEGVSSVLLGSSNPEQL 392

  Fly   507 HQSLQSLQLLPRLSSSVMLELERILENKP 535
            .::|.::|:||:::|.::.|::.||.|||
 Frog   393 IENLGAIQVLPKMTSHIVNEVDNILGNKP 421

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hk	NP_001259401.1	Kv_beta	205..531	CDD:213602	161/334 (48%)
		Aldo_ket_red	218..531	CDD:278668	151/321 (47%)
kcnab1	XP_012818504.1	Kv_beta	101..417	CDD:213602	161/334 (48%)
		Aldo_ket_red	101..416	CDD:119408	161/333 (48%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	300	1.000	Domainoid score	I1407
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H56491
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000530
OrthoInspector	1	1.000	-	-		otm49174
Panther	1	1.100	-	-	O	PTHR43150
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X715
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	7	7.010