Protein Alignment Hk and Akr1c13

DIOPT Version :10

• Sequence 1: NP_001259401.1
• Gene: Hk / 31955
• FlyBaseID: FBgn0263220
• Length: 887
• Species: Drosophila melanogaster
• Sequence 2: XP_006254252.1
• Gene: Akr1c13 / 361266
• RGDID: 1308232
• Length: 371
• Species: Rattus norvegicus
• Alignment Length: 376
• Identity: 82/376 - (21%)
• Similarity: 143/376 - (38%)
• Gaps: 118/376 - (31%)

  Fly   227 SPGVS--------DDQAEAILKLAIESGINLFDISEAHS-ETEIGKILQ---RAG-WKRTAYVIT 278
            |||||        ....|| ..|||::|....|.:.|:. |.|||:.:|   :|| .||....||
  Rat    67 SPGVSASYKLVPKSKSLEA-AHLAIDAGYRHIDTAYAYQIEEEIGQAIQSKIKAGVVKREDMFIT 130

  Fly   279 TKVYWSTKSEERGLSRKHIIE-CVRASLQRLQLQYIDIVIIHKADPM------CPMEVVRAMSYV 336
            ||: |.|      ..|..::: .:..||:.|||.|.|:.|:|...||      .|::
  Rat   131 TKL-WCT------CFRPELVKPALEKSLKNLQLDYADLYIMHYPVPMKSGDNDFPVD-------- 180

  Fly   337 IQQGWAM-----YWGTARWSQVEIMEAYTNCRQFNCITPIVEQS---------------EYHMFC 381
             ::|.::     :..|  |..:|      .|:....:..|...:               :|...|
  Rat   181 -EKGKSLLDTVDFCDT--WEMLE------KCKDAGLVKSIGVSNFNHKQLERLLNKPGLKYKPVC 236

  Fly   382 RE-KCELYLPEMYNKIGVGLMAWGPLSMALSDTQNGDKLFLPKGSFKTKSF-SWTEDEINRNAAL 444
            .: :|.|||.:               |..|...::.|.:.:..|:..|:.: .|    :::|:.:
  Rat   237 NQVECHLYLNQ---------------SKLLDYCKSKDIVLVAYGALGTQRYKEW----VDQNSPV 282

  Fly   445 SPQGSWGKDRIDEGRRHCDRLRD--LAALAEKLGCSPTQLSIAWSLKHEPVQCLLLGATSAEQLH 507
                               .|.|  |..:|:|...||..:::.:.::...|.  |..:....::.
  Rat   283 -------------------LLNDPVLCDVAKKNKRSPALIALRYLVQRGVVP--LAQSFKENEMR 326

  Fly   508 QSLQSLQLLPRLSSSVMLELERILENKPVRPPMISTLALRXQSACPQGPLS 558
            ::||....  :||...|..|:.:  ||..|     .|:.. .:..|:.|.|
  Rat   327 ENLQVFDF--QLSPEDMKTLDGL--NKNFR-----YLSAEFLAGHPEYPFS 368

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hk	NP_001259401.1	AKR_AKR6B1	203..535	CDD:381368	76/351 (22%)
Akr1c13	XP_006254252.1	AKR_AKR1C1-35	77..356	CDD:381334	74/352 (21%)