Protein Alignment Hk and Akr1c2

DIOPT Version :10

• Sequence 1: NP_001259401.1
• Gene: Hk / 31955
• FlyBaseID: FBgn0263220
• Length: 887
• Species: Drosophila melanogaster
• Sequence 2: NP_001427047.1
• Gene: Akr1c2 / 291283
• RGDID: 1311841
• Length: 323
• Species: Rattus norvegicus
• Alignment Length: 366
• Identity: 78/366 - (21%)
• Similarity: 149/366 - (40%)
• Gaps: 111/366 - (30%)

  Fly   218 VGLGTWPVFSPGVSDDQAEAILKLAIESGINLFDISEAH-SETEIGKILQRA---GWKRTAYVIT 278
            :|.||  .....:...:|:.:.|:||::|.:.||.:..: :|..:|:.::..   |..|...:..
  Rat    19 LGFGT--AMPSELPKSKAKEVTKIAIDAGFHHFDSAFVYNTEDHVGEAIREKIANGTTRREDIFY 81

  Fly   279 TKVYWSTKSEERGLSRKHIIECVRASLQRLQLQYIDIVIIHKADPMCPMEVVRAMSYVIQQGWAM 343
            |...|.| |....|.|.. :||   ||::|||.|:|:.:||....:.|.:    .::.:.:...:
  Rat    82 TSKLWCT-SLHPELVRSS-LEC---SLKKLQLDYVDLYLIHFPMALKPGD----ENFPVDEHGKL 137

  Fly   344 YWGT----ARWSQVEIMEAYTNCR-----------QFN--CITPIVEQS--EYHMFCRE-KCELY 388
            .:.|    |.|      ||...|:           .||  .:..|:.:.  :|...|.: :|.||
  Rat   138 LFDTVDLCATW------EAMEKCKDAGLAKSIGVSNFNRRQLEKILNKPGLKYKPVCNQVECHLY 196

  Fly   389 LPEMYNKI-------GVGLMAWGPLSMALSDTQNGDKLFLPKGSFKTKSFSWTEDEINRNAALSP 446
            |.:|  |:       |:.|:|:|.|.   :...||                |    :::|:.:
  Rat   197 LNQM--KLLDFCKTNGIILVAYGVLG---TQRYNG----------------W----VDQNSPV-- 234

  Fly   447 QGSWGKDRIDEGRRHCDRLRD--LAALAEKLGCSPTQLSIAWSLKHEPVQCLLLGATS--AEQLH 507
                             .|.:  |:::|:|...:|..:    :|:|:..:.:::..||  .|::.
  Rat   235 -----------------LLNEPVLSSMAKKYNQTPALI----ALRHQLQRGIVVLNTSLKEERIK 278

  Fly   508 QSLQ--SLQLLPRLSSSVMLELER--------ILENKPVRP 538
            ::::  ..||.|. ...|:.:|.|        |.|..|..|
  Rat   279 ENMKVFEFQLSPE-DMKVLDDLNRNLRYIAGGIFEGHPNFP 318

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hk	NP_001259401.1	AKR_AKR6B1	203..535	CDD:381368	76/361 (21%)
Akr1c2	NP_001427047.1	None