Protein Alignment Hk and Akr7a3

DIOPT Version :10

• Sequence 1: NP_001259401.1
• Gene: Hk / 31955
• FlyBaseID: FBgn0263220
• Length: 887
• Species: Drosophila melanogaster
• Sequence 2: NP_037347.1
• Gene: Akr7a3 / 26760
• RGDID: 628635
• Length: 327
• Species: Rattus norvegicus
• Alignment Length: 324
• Identity: 73/324 - (22%)
• Similarity: 122/324 - (37%)
• Gaps: 90/324 - (27%)

  Fly   250 FDISEAHSETEIGKI---LQRAGWKRTAYVITTKVYWSTKSEE---RGLSRKHIIECVRASLQRL 308
            |..:...|||.:|.:   |.|:|         .||..:||:..   :.|....:...:..||:||
  Rat    43 FVYANGQSETILGDLGLGLGRSG---------CKVKIATKAAPMFGKTLKPADVRFQLETSLKRL 98

  Fly   309 QLQYIDIVIIHKADPMCPM-EVVRAMSYVIQQGWAMYWGTARWSQVEIMEAYTNCRQFNCITPIV 372
            |...:|:..:|..|...|: |.::|...:.|:|..:..|.:.:...|:.|..|.|::...|.|.|
  Rat    99 QCPRVDLFYLHFPDHGTPIEETLQACHQLHQEGKFVELGLSNYVSWEVAEICTLCKKNGWIMPTV 163

  Fly   373 EQSEYHMFCRE-KCELYLPEMYNKIGVGLMAWGPLSMAL---------SDTQNGDKLFLPKGSFK 427
            .|..|:...|: :.||:  ......|:...|:.||:..|         .|.:|      |:..|.
  Rat   164 YQGMYNAITRQVETELF--PCLRHFGLRFYAFNPLAGGLLTGRYKYQDKDGKN------PESRFF 220

  Fly   428 TKSFS-------WTEDEINRNAALSPQGSWGKDRIDEGRRHCDRLRDLAALAEKLG-CSPTQLSI 484
            ...||       |.|:..|..|.:.                       .||....| .:|:.:|.
  Rat   221 GNPFSQLYMDRYWKEEHFNGIALVE-----------------------KALKTTYGPTAPSMISA 262

  Fly   485 A--WSLKHEPVQ-----CLLLGATSAEQLHQSLQSLQLLPRLSSSVMLELERILENKPVRPPMI 541
            |  |...|..::     .::||.:|.|||.|:|                  .::|..|:.|.::
  Rat   263 AVRWMYHHSQLKGTQGDAVILGMSSLEQLEQNL------------------ALVEEGPLEPAVV 308

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hk	NP_001259401.1	AKR_AKR6B1	203..535	CDD:381368	71/316 (22%)
Akr7a3	NP_037347.1	AKR_AKR7A1-5	6..315	CDD:381301	73/324 (23%)