Protein Alignment Hk and osr2

DIOPT Version :10

• Sequence 1: NP_001259401.1
• Gene: Hk / 31955
• FlyBaseID: FBgn0263220
• Length: 887
• Species: Drosophila melanogaster
• Sequence 2: NP_588516.1
• Gene: osr2 / 2539573
• PomBaseID: SPCC965.06
• Length: 344
• Species: Schizosaccharomyces pombe
• Alignment Length: 341
• Identity: 118/341 - (34%)
• Similarity: 201/341 - (58%)
• Gaps: 26/341 - (7%)

  Fly   205 YKNLGKSGLRISNVGLGTWPVF-SPGVSDDQAEAILKLAIESGINLFDISE----AHSETEIGKI 264
            ::.||:|||::|...||.|..: :.|...:..:..||.|.:.|||.||.:|    .:|||.:||.
pombe    15 FRFLGRSGLKVSAFSLGGWLTYGNEGYDVEHTKNCLKQAWDLGINTFDTAEIYSNGNSETVMGKA 79

  Fly   265 LQRAGWKRTAYVITTKVYWSTKSE---ERGLSRKHIIECVRASLQRLQLQYIDIVIIHKADPMCP 326
            ::..||.|:.|||||||::...::   ..|||||||||.:.|||:||.|.|:|:::.|:.||..|
pombe    80 IKELGWDRSEYVITTKVFFGAGTKLPNTTGLSRKHIIEGLNASLKRLGLPYVDVIMAHRPDPSVP 144

  Fly   327 M-EVVRAMSYVIQQGWAMYWGTARWSQVEIMEAYTNCRQFNCITPIVEQSEYHMFCREKCELYLP 390
            | |||||.:.:||.|.|.||||:.||..||..|:....::|.|.|:.:|.:|:...|:..|..|.
pombe   145 MEEVVRAFTQLIQDGKAFYWGTSEWSAFEIEHAHHIATKYNLIAPVADQPQYNYLTRDHFEKDLL 209

  Fly   391 EMYNKIGVGLMAWGPLSMALSDTQNGDKLFLPKGSFKTKSFSWTEDEINRNAALSPQGSWGKDRI 455
            .:....|.|...|.||...:...:..|.  :|:||..:.:|:          :|:     |:.:.
pombe   210 PLQQIYGYGATVWSPLKSGILTGKYNDG--IPEGSRLSTTFT----------SLA-----GQLQT 257

  Fly   456 DEGRRHCDRLRDLAALAEKLGCSPTQLSIAWSLKHEPVQCLLLGATSAEQLHQSLQSLQLLPRLS 520
            .||:...|::|.::.:||::|.:|:||::||:||:..|...:|||:..||:.:::::::.:.:|:
pombe   258 PEGKTQLDQVRQISKIAEQIGATPSQLALAWTLKNPYVSTTILGASKPEQIVENVKAVEFIDKLT 322

  Fly   521 SSVMLELERILENKPV 536
            ..::.:::.||...|:
pombe   323 PEILKKIDEILNFTPL 338

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hk	NP_001259401.1	AKR_AKR6B1	203..535	CDD:381368	117/338 (35%)
osr2	NP_588516.1	AKR_AKR6C1_2	14..332	CDD:381369	115/333 (35%)