Protein Alignment Hk and exc-15

DIOPT Version :10

• Sequence 1: NP_001259401.1
• Gene: Hk / 31955
• FlyBaseID: FBgn0263220
• Length: 887
• Species: Drosophila melanogaster
• Sequence 2: NP_001367925.1
• Gene: exc-15 / 178844
• WormBaseID: WBGene00020369
• Length: 333
• Species: Caenorhabditis elegans
• Alignment Length: 265
• Identity: 62/265 - (23%)
• Similarity: 106/265 - (40%)
• Gaps: 80/265 - (30%)

  Fly   211 SGLRISNVGLGTWPVFSPGVSDDQAE--AILKLAIESGINLFDISEAH-SETEIGKILQR----A 268
            :|.::...|||||.|      .|:||  ..|:.|:::|..|.|.:..: :|..|||:|..    .
 Worm    10 TGAQLPLFGLGTWQV------KDEAELTVALRAALDAGYRLIDTAHLYQNEHIIGKVLHEYISSG 68

  Fly   269 GWKRTAYVITTKVYWSTKSEERGLSRKHIIECVRASLQRLQLQYIDIVIIHKADPMCP------- 326
            ..||....:|:|:.::..:.|      .:.:||.:.|:.|||:|||:.:||     ||
 Worm    69 KLKREDIFVTSKLPFTAHAPE------DVPKCVESQLKALQLEYIDLYLIH-----CPFPFKHQE 122

  Fly   327 -------------------MEVVRAMSYVIQQGWAMYWGTARWSQVEIMEAYTNCRQFNCITPIV 372
                               ::..||:..:.::|.....|.:.:|..::...|....    :.|..
 Worm   123 GSFAPLMENGELAVTEIAHIDTWRALEKLYKEGKLKALGVSNFSCNQLQALYDAAE----VKPAN 183

  Fly   373 EQSEYHMFCREKCELYLPE-----MYNKIGVGLMAWGPLSMALSDTQNGDKLFLPKGSFKTKSFS 432
            :|.|        |.:|.|:     :..|:||.:.|:.||.      ..|.|...|.|       .
 Worm   184 QQVE--------CHIYWPQQELRALCKKLGVTVTAYAPLG------SPGRKAARPDG-------V 227

  Fly   433 WTEDE 437
            |.|.:
 Worm   228 WPEGD 232

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hk	NP_001259401.1	AKR_AKR6B1	203..535	CDD:381368	62/265 (23%)
exc-15	NP_001367925.1	AKR_AKR1G1_CeAKR	3..306	CDD:381380	62/265 (23%)