Protein Alignment Hk and Akr7a2

DIOPT Version :10

• Sequence 1: NP_001259401.1
• Gene: Hk / 31955
• FlyBaseID: FBgn0263220
• Length: 887
• Species: Drosophila melanogaster
• Sequence 2: NP_599234.1
• Gene: Akr7a2 / 171445
• RGDID: 620311
• Length: 338
• Species: Rattus norvegicus
• Alignment Length: 387
• Identity: 89/387 - (22%)
• Similarity: 146/387 - (37%)
• Gaps: 94/387 - (24%)

  Fly   180 SRSISLGSNPALPLRHGSTPTPGLRYKNLGKSGLRISNVGLGTWPVFSPGVSDDQAEAILKLAIE 244
            |||.:..:....|||.|:.                     |||..: ...:....:.|.::..:|
  Rat     2 SRSPAPRAVSGAPLRPGTV---------------------LGTMEM-GRRMDASASAATVRAFLE 44

  Fly   245 SGINLFDIS----EAHSETEIGKILQRAGWKRTAYVITTKVY-WSTKSEERGLSRKHIIECVRAS 304
            .|:|..|.:    :..||:.:|.:....|.......|.||.. |..||    |....:...:..|
  Rat    45 RGLNELDTAFMYCDGQSESILGSLGLGLGSGDCTVKIATKANPWDGKS----LKPDSVRSQLETS 105

  Fly   305 LQRLQLQYIDIVIIHKADPMCP-MEVVRAMSYVIQQGWAMYWGTARWSQVEIMEAYTNCRQFNCI 368
            |:|||...:|:..:|..|...| :|.::|...:.|:|..:..|.:.::..|:.|.||.|:....|
  Rat   106 LKRLQCPRVDLFYLHAPDHGTPIVETLQACQQLHQEGKFVELGLSNYASWEVAEIYTLCKSNGWI 170

  Fly   369 TPIVEQSEYHMFCREKCELYLPEMYNKIGVGLMAWGPLSMAL------SDTQNGDKLFLPKGSFK 427
            .|.|.|..|:...|: .|..|.......|:...|:.||:..|      .:.::|.:   |:|.|.
  Rat   171 LPTVYQGMYNATTRQ-VETELLPCLRYFGLRFYAYNPLAGGLLTGKYRYEDKDGKQ---PEGRFF 231

  Fly   428 TKSFSWTEDEINRNAALSPQGSWGKDRIDEGRRHCDRLRDLAALAEKL--------GCSPTQLSI 484
            ..  ||:|...||        .|.:       .|.:.:    ||.||.        ..|.|..::
  Rat   232 GN--SWSETYRNR--------FWKE-------HHFEAI----ALVEKALKTTYGTSAPSMTSAAL 275

  Fly   485 AWSLKHEPVQ-----CLLLGATSAEQLHQSLQSLQLLPRLSSSVMLELERILENKPVRPPMI 541
            .|...|..:|     .::||.:|.|||.|:|.:                  .|..|:.|.::
  Rat   276 RWMYHHSQLQGTRGDAVILGMSSLEQLEQNLAA------------------TEEGPLEPAVV 319

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hk	NP_001259401.1	AKR_AKR6B1	203..535	CDD:381368	80/356 (22%)
Akr7a2	NP_599234.1	AKR_AKR7A1-5	17..326	CDD:381301	83/372 (22%)