Protein Alignment Hk and Kcnab3

DIOPT Version :9

• Sequence 1: NP_001259401.1
• Gene: Hk / 31955
• FlyBaseID: FBgn0263220
• Length: 887
• Species: Drosophila melanogaster
• Sequence 2: NP_034729.3
• Gene: Kcnab3 / 16499
• MGIID: 1336208
• Length: 404
• Species: Mus musculus
• Alignment Length: 353
• Identity: 165/353 - (46%)
• Similarity: 236/353 - (66%)
• Gaps: 24/353 - (6%)

  Fly   189 PALPLRHGSTPTPGLRYKNLGKSGLRISNVGLGTWPVFSPGVSDDQAEAILKLAIESGINLFDIS 253
            ||..||..:....|::|:||||||||:|.:|||||..|...:||:.||.:|.:|.|.|:||||.:
Mouse    64 PAGALRESTGRGTGMKYRNLGKSGLRVSCLGLGTWVTFGSQISDETAEDLLTVAYEHGVNLFDTA 128

  Fly   254 EAH----SETEIGKILQRAGWKRTAYVITTKVYWSTKSE-ERGLSRKHIIECVRASLQRLQLQYI 313
            |.:    :|..:|.||:..||:|::||||||::|..::| |||||||||||.::.||.||||:|:
Mouse   129 EVYAAGKAERTLGNILKSKGWRRSSYVITTKIFWGGQAETERGLSRKHIIEGLQGSLDRLQLEYV 193

  Fly   314 DIVIIHKADPMCPM-EVVRAMSYVIQQGWAMYWGTARWSQVEIMEAYTNCRQFNCITPIVEQSEY 377
            |||..:::||..|| |:||||:|||.||.|:||||:|||..||||||:..||||.|.|:.||:|.
Mouse   194 DIVFANRSDPNSPMEEIVRAMTYVINQGLALYWGTSRWSAAEIMEAYSMARQFNLIPPVCEQAEN 258

  Fly   378 HMFCREKCELYLPEMYNKIGVGLMAWGPLSMALSDTQNGDKLFLPKGSFKT-KSFSWTEDEINRN 441
            |.|.|||.|:.|||:|:|||||.:.|.||:..|..::...:  :|.....| |.:.|.::::
Mouse   259 HFFQREKVEMQLPELYHKIGVGSVTWSPLACGLITSKYDGR--VPDTCKATVKGYQWLKEKV--- 318

  Fly   442 AALSPQGSWGKDRIDEGRRHCDRLRDLAALAEKLGCSPTQLSIAWSLKHEPVQCLLLGATSAEQL 506
                        :.:||::...|:.||...|.:|||:..||:|||.|:.|.|..:|||.:|||||
Mouse   319 ------------QSEEGKKQQARVMDLLPTARQLGCTVAQLAIAWCLRSEGVSSVLLGVSSAEQL 371

  Fly   507 HQSLQSLQLLPRLSSSVMLELERILENK 534
            .:.|.|||:|.:|:...::|::.:|.||
Mouse   372 MEHLGSLQVLSQLTPQTVVEIDALLGNK 399

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hk	NP_001259401.1	Kv_beta	205..531	CDD:213602	157/332 (47%)
		Aldo_ket_red	218..531	CDD:278668	147/319 (46%)
Kcnab3	NP_034729.3	Kv_beta	80..396	CDD:213602	157/332 (47%)
		Aldo_ket_red	80..395	CDD:119408	157/331 (47%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	302	1.000	Domainoid score	I1397
eggNOG	1	0.900	-	-		E1_COG0667
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000530
OrthoInspector	1	1.000	-	-		otm44000
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	LDO	PTHR43150
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R634
SonicParanoid	1	1.000	-	-		X715
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	9	8.900