Protein Alignment Hk and Kcnab1

DIOPT Version :9

• Sequence 1: NP_001259401.1
• Gene: Hk / 31955
• FlyBaseID: FBgn0263220
• Length: 887
• Species: Drosophila melanogaster
• Sequence 2: NP_001344287.1
• Gene: Kcnab1 / 16497
• MGIID: 109155
• Length: 419
• Species: Mus musculus
• Alignment Length: 428
• Identity: 181/428 - (42%)
• Similarity: 270/428 - (63%)
• Gaps: 32/428 - (7%)

  Fly   118 TGPTTQQLMIGNGAMGVIPSTNDSNNNNNNNNNVDNTSDES-NPVTIYRCRAPIASLDCMEEFSR 181
            ||....|:...|.........:....:.:.....:|..|.| :|....:.||...:|....|.:.
Mouse     6 TGAAGSQISEDNSKFRKQSGLSSGGKDRSPKKAPENAKDSSLSPTGQSQLRARQLALLREVEMNW 70

  Fly   182 SISLGSNPALPLRHGSTPTPGLRYKNLGKSGLRISNVGLGTWPVFSPGVSDDQAEAILKLAIESG 246
            .:.|..   |...|.:..|.|:.::||||||||:|.:|||||..|...:||:.||.::.:|.|||
Mouse    71 YLKLCE---LSSEHTTAHTTGMPHRNLGKSGLRVSCLGLGTWVTFGGQISDEVAERLMTIAYESG 132

  Fly   247 INLFDISEAH----SETEIGKILQRAGWKRTAYVITTKVYWSTKSE-ERGLSRKHIIECVRASLQ 306
            :||||.:|.:    :|..:|.|:::.||:|::.|||||:||..|:| |||||||||||.::.|||
Mouse   133 VNLFDTAEVYAAGKAEVILGSIIKKKGWRRSSLVITTKLYWGGKAETERGLSRKHIIEGLKGSLQ 197

  Fly   307 RLQLQYIDIVIIHKADPMCPM-EVVRAMSYVIQQGWAMYWGTARWSQVEIMEAYTNCRQFNCITP 370
            ||||:|:|:|..::.|...|| |:||||::||.||.||||||:|||.:||||||:..||||.|.|
Mouse   198 RLQLEYVDVVFANRPDSNTPMEEIVRAMTHVINQGMAMYWGTSRWSAMEIMEAYSVARQFNMIPP 262

  Fly   371 IVEQSEYHMFCREKCELYLPEMYNKIGVGLMAWGPLSMALSDTQNGDKLFLPKGS-FKTKSFSWT 434
            :.||:|||:|.|||.|:.|||:|:|||||.|.|.||:..:...:.|:.  :|:.| ...|.:.|.
Mouse   263 VCEQAEYHLFQREKVEVQLPELYHKIGVGAMTWSPLACGIISGKYGNG--VPESSRASLKCYQWL 325

  Fly   435 EDEINRNAALSPQGSWGKDRI--DEGRRHCDRLRDLAALAEKLGCSPTQLSIAWSLKHEPVQCLL 497
                             |:||  :|||:..::|:||:.:||:|||:..||::||.|::|.|..:|
Mouse   326 -----------------KERIVSEEGRKQQNKLKDLSPIAERLGCTLPQLAVAWCLRNEGVSSVL 373

  Fly   498 LGATSAEQLHQSLQSLQLLPRLSSSVMLELERILENKP 535
            ||:::.|||.::|.::|:||:::|.|:.|::.||.|||
Mouse   374 LGSSTPEQLIENLGAIQVLPKMTSHVVNEIDNILRNKP 411

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hk	NP_001259401.1	Kv_beta	205..531	CDD:213602	159/334 (48%)
		Aldo_ket_red	218..531	CDD:278668	150/321 (47%)
Kcnab1	NP_001344287.1	Kv_beta	91..407	CDD:213602	159/334 (48%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	302	1.000	Domainoid score	I1397
eggNOG	1	0.900	-	-		E1_COG0667
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H56491
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000530
OrthoInspector	1	1.000	-	-		otm44000
orthoMCL	1	0.900	-	-		OOG6_100387
Panther	1	1.100	-	-	O	PTHR43150
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R634
SonicParanoid	1	1.000	-	-		X715
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	11	10.800