Protein Alignment Hk and Akr7a5

DIOPT Version :10

• Sequence 1: NP_001259401.1
• Gene: Hk / 31955
• FlyBaseID: FBgn0263220
• Length: 887
• Species: Drosophila melanogaster
• Sequence 2: NP_079613.3
• Gene: Akr7a5 / 110198
• MGIID: 107796
• Length: 367
• Species: Mus musculus
• Alignment Length: 381
• Identity: 89/381 - (23%)
• Similarity: 145/381 - (38%)
• Gaps: 78/381 - (20%)

  Fly   186 GSNPALPLRHGSTPTPGLRYKNLGKSGLRISNVGLGTWPVFSPGVSDDQAEAILKLAIESGINLF 250
            |::...||.....|.|    :....:.||.:.| |||..: ...:....:.|.::..:|.|.:..
Mouse    21 GTSVGRPLAMSRPPPP----RAASGAPLRPATV-LGTMEM-GRRMDASASAASVRAFLERGHSEL 79

  Fly   251 DIS----EAHSETEIGKILQRAGWKRTAYVITTKVY-WSTKSEERGLSRKHIIECVRASLQRLQL 310
            |.:    :..||..:|.:....|.......|.||.. |..||    |....|...:..||:|||.
Mouse    80 DTAFMYCDGQSENILGGLGLGLGSGDCTVKIATKANPWEGKS----LKPDSIRSQLETSLKRLQC 140

  Fly   311 QYIDIVIIHKADPMCPM-EVVRAMSYVIQQGWAMYWGTARWSQVEIMEAYTNCRQFNCITPIVEQ 374
            ..:|:..:|..|...|: |.:||...:.|:|..:..|.:.::..|:.|..|.|:....|.|.|.|
Mouse   141 PRVDLFYLHAPDHSTPVEETLRACHQLHQEGKFVELGLSNYASWEVAEICTLCKSNGWILPTVYQ 205

  Fly   375 SEYHMFCREKCELYLPEMYNKIGVGLMAWGPLSMAL------SDTQNGDKLFLPKGSFKTKSFSW 433
            ..|:...|: .|..|.......|:...|:.||:..|      .:.::|.:   |.|.|...  :|
Mouse   206 GMYNATTRQ-VEAELLPCLRHFGLRFYAYNPLAGGLLTGKYKYEDKDGKQ---PVGRFFGN--NW 264

  Fly   434 TEDEINRNAALSPQGSWGKDRIDEGRRHCDRLRDLAALAEK-----LGCSP---TQLSIAWSLKH 490
            .|...||        .|.:       .|.:.:    ||.||     .|.:.   |..::.|...|
Mouse   265 AETYRNR--------FWKE-------HHFEAI----ALVEKALQTTYGTNAPRMTSAALRWMYHH 310

  Fly   491 EPVQ-----CLLLGATSAEQLHQSLQSLQLLPRLSSSVMLELERILENKPVRPPMI 541
            ..:|     .::||.:|.|||.|:|.:                  .|..|:.|.::
Mouse   311 SQLQGTRGDAVILGMSSLEQLEQNLAA------------------TEEGPLEPAVV 348

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hk	NP_001259401.1	AKR_AKR6B1	203..535	CDD:381368	82/356 (23%)
Akr7a5	NP_079613.3	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..45		5/27 (19%)
		AKR_AKR7A1-5	46..355	CDD:381301	82/352 (23%)