Protein Alignment Hk and Akr1c14

DIOPT Version :10

• Sequence 1: NP_001259401.1
• Gene: Hk / 31955
• FlyBaseID: FBgn0263220
• Length: 887
• Species: Drosophila melanogaster
• Sequence 2: NP_598833.1
• Gene: Akr1c14 / 105387
• MGIID: 2145458
• Length: 323
• Species: Mus musculus
• Alignment Length: 212
• Identity: 49/212 - (23%)
• Similarity: 76/212 - (35%)
• Gaps: 60/212 - (28%)

  Fly   215 ISNVGLGTWPVFSPGVSDDQAEAILKLAIESGINLFDISEAHS-ETEIGKILQ---RAGWKRTAY 275
            |..:|.||  .....|..|:.....|:||::|...||.:..:. |.|:|:.::   ..|..:...
Mouse    16 IPALGFGT--TVPDKVPKDELIKATKIAIDTGFRHFDSAYLYQIEEEVGQAIRSKIEDGTVKRED 78

  Fly   276 VITTKVYWSTKSEERGLSRKHII-ECVRASLQRLQLQYIDIVIIH------KADPMCP------- 326
            :..|...|||      ..|..:: .|:..:|:..||.|:|:.|||      ..|.:.|
Mouse    79 IFYTSKLWST------FHRPELVRSCLEKTLKNAQLDYVDLYIIHFPMALQPGDKLFPRDEHGKL 137

  Fly   327 -MEVV------RAMSYVIQQGWAMYWGTARWSQVEIMEAYTNCRQFNCI--------TPIVEQSE 376
             .|.|      .||......|.|...|.:.:          |.||...|        .|:..|.|
Mouse   138 LAEAVDLCDTWEAMEKCKDAGLAKSIGVSNF----------NFRQLETILNKPGLKYKPVCNQVE 192

  Fly   377 YHM---------FCREK 384
            .|:         :|:.|
Mouse   193 CHLYLNQSQMLDYCKSK 209

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hk	NP_001259401.1	AKR_AKR6B1	203..535	CDD:381368	49/212 (23%)
Akr1c14	NP_598833.1	AKR_AKR1C1-35	6..308	CDD:381334	49/212 (23%)