Protein Alignment Hk and kcnab2

DIOPT Version :10

• Sequence 1: NP_001259401.1
• Gene: Hk / 31955
• FlyBaseID: FBgn0263220
• Length: 887
• Species: Drosophila melanogaster
• Sequence 2: XP_017950940.2
• Gene: kcnab2 / 100486636
• XenbaseID: XB-GENE-990281
• Length: 455
• Species: Xenopus tropicalis
• Alignment Length: 444
• Identity: 191/444 - (43%)
• Similarity: 276/444 - (62%)
• Gaps: 55/444 - (12%)

  Fly   117 ITGPTTQQL-MIGNGAMGVIPSTNDSNNNNNNNNNVDNTSDESNPVTIYRCR--APIASLDCMEE 178
            |..|.::.| |..:|::..:.|...|:...|..:.||       .|.:.|.|  ...|.:..|||
 Frog    34 IPRPDSKMLSMSYSGSLKSVLSRYHSDWGINQVHQVD-------VVELQRLREVRVAAHVKNMEE 91

  Fly   179 FSRSISLGSNPALPLRHGSTPTPGLRYKNLGKSGLRISNVGLGTWPVFSPGVSDDQAEAILKLAI 243
            |.:...|..|..      :....|::|:||||||||:|.:|||||..|...::|:.||.::.||.
 Frog    92 FLKMHGLSLNEC------TARKTGMKYRNLGKSGLRVSCLGLGTWVTFGGQITDEMAEQLMTLAY 150

  Fly   244 ESGINLFDISEAH----SETEIGKILQRAGWKRTAYVITTKVYWSTKSE-ERGLSRKHIIECVRA 303
            ::||||||.:|.:    :|..:|.|:::.||:|::.|||||::|..|:| |||||||||||.::|
 Frog   151 DNGINLFDTAEVYAAGKAEVVLGNIIKKKGWRRSSLVITTKIFWGGKAETERGLSRKHIIEGLKA 215

  Fly   304 SLQRLQLQYIDIVIIHKADPMCPM----------------EVVRAMSYVIQQGWAMYWGTARWSQ 352
            ||:||||.|:|:|..::.||..||                |.||||::||.||.||||||:|||.
 Frog   216 SLERLQLDYVDVVFANRPDPNTPMEGDPFSSSKSRTFIIEETVRAMTHVINQGMAMYWGTSRWSS 280

  Fly   353 VEIMEAYTNCRQFNCITPIVEQSEYHMFCREKCELYLPEMYNKIGVGLMAWGPLSMAL-SDTQNG 416
            :||||||:..||||.|.||.||:|||||.|||.|:.|||:::|||||.|.|.||:..: |...:|
 Frog   281 MEIMEAYSVARQFNLIPPICEQAEYHMFQREKVEVQLPELFHKIGVGAMTWSPLACGIVSGKYDG 345

  Fly   417 DKLFLPKGSFKTKSFSWTEDEINRNAALSPQGSWGKDRIDEGRRHCDRLRDLAALAEKLGCSPTQ 481
            .  ..|......|.:.|.:|:|     ||          :||||...:|::|.|:||:|||:..|
 Frog   346 G--IPPYSRASLKGYQWLKDKI-----LS----------EEGRRQQAKLKELQAIAERLGCTLPQ 393

  Fly   482 LSIAWSLKHEPVQCLLLGATSAEQLHQSLQSLQLLPRLSSSVMLELERILENKP 535
            |:|||.|::|.|..:||||::|:||.:::.::|:||:||||::.|::.||.|||
 Frog   394 LAIAWCLRNEGVSSVLLGASNADQLLENIGAIQVLPKLSSSIIHEIDSILGNKP 447

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hk	NP_001259401.1	AKR_AKR6B1	203..535	CDD:381368	168/353 (48%)
kcnab2	XP_017950940.2	Aldo_ket_red_shaker	111..435	CDD:381367	163/340 (48%)