|
Fly 1 MYSEWASLSAQITANSCGAQCFSVLNKFPASAGREVVVSVVKQLGTNLGITQNAEPSHLVK-DEE 64
|||||.||.. :..|..|.. |||:.:|.|.||||..:||:.||..||....|...:|:| |:|
Human 1 MYSEWRSLHL-VIQNDQGHT--SVLHSYPESVGREVANAVVRPLGQVLGTPSVAGSENLLKTDKE 62
Fly 65 VKWCMDVICFGLSLPLQEHETIKDCVNVYCEWLTALHPQPRISVPKPICEDANLYARQIINHFHN 129
|||.|:|||:||:||| :.||:|.||:||.:|:.|| ..|:.|:|.|:.::.|.|.:.|:.|..|
Human 63 VKWTMEVICYGLTLPL-DGETVKYCVDVYTDWIMAL-VLPKDSIPLPVIKEPNQYVQTILKHLQN 125
Fly 130 LFVPRQGEILPFLYQTTLGADTIKRQAVLCHRVLRTLQQTAQISQLMDRQTWDTLLLFLLAINEI 194
||||||.: |:..|: ||.:|||.:|:.|:.|.||.|:||:.||||||.||:|
Human 126 LFVPRQEQ----------GSSQIR----LCLQVLRAIQKLARESSLMARETWEVLLLFLLQINDI 176
Fly 195 LLAPPTVKDDVGDQLCERVLSVLFEVWLLACVRSFPSPSMWKTLQESCAMWRHRVALVDQWNRVN 259
|||||||:..:.:.|.|:::.||||||||||.|.||:|..|||.:|..|.|||..|:|:||::|.
Human 177 LLAPPTVQGGIAENLAEKLIGVLFEVWLLACTRCFPTPPYWKTAKEMVANWRHHPAVVEQWSKVI 241
Fly 260 LALTARLLEFSYGPAFPQLKNADEDGQLIPIGMSNDCVAQTWYRFLRMIGNPTALCSPHIISKSS 324
.|||:|||.|:|||:||..|..|||..|||..|.|:||||||:|||.|:.||..|.:|.|||.:.
Human 242 CALTSRLLRFTYGPSFPAFKVPDEDASLIPPEMDNECVAQTWFRFLHMLSNPVDLSNPAIISSTP 306
Fly 325 HFVQWALTHEKG--AETHQHPCLQQLPQIFLNAMKGISSQVDAFLGVYQPPPQQTDGVVTNLLEI 387
.| |....:..| .|.:|:|||:.|||||..||:|||..||||||:.:|
Human 307 KF-QEQFLNVSGMPQELNQYPCLKHLPQIFFRAMRGISCLVDAFLGISRP--------------- 355
Fly 388 RHSLNEATSSTLQQFIHSSSATNIANQQNQPAHHHHHLHYPHLHLHGAGSFLRDNFMSNSASSAL 452
.|:||
Human 356 --------------------------------------------------------RSDSA---- 360
Fly 453 NAIMGHHGGHHGHHHQQQQQQQQQLQISASPTSSLTTSGSSAVGSTSAGGSHSAGVVGSISFGAT 517
..:|.:.|:...|:||.:
Human 361 ---------------------------PPTPVNRLSMPQSAAVST-------------------- 378
Fly 518 ESPGPGQASASATPTPPLQRRLAKSFSVAPTITQQKGLSKTSLIGLTGGGARNAISSSSTTTTNA 582
|||..|| ...:|..|...|||.:. |...::....:|||
Human 379 --------------TPPHNRR-------HRAVTVNKATMKTSTVS-TAHASKVQHQTSST----- 416
Fly 583 GSTGGTGSGDGSAPAPLPTTPTSTSGPPSASSSINSLPLTSMGAGVELAVARPKCNSILHVFHEW 647
:|| ::|..||..| ..|| |..|||.||||::|..|
Human 417 --------------SPL-SSPNQTSSEP------RPLP----------APRRPKVNSILNLFGSW 450
Fly 648 LFEAAHIGGDTWRQNRKKQACE---ASKRPSSMI-------------------MEHRKGSISLSQ 690
||:||.: .|: ...|.|||. ||.|:....:|.
Human 451 LFDAAFV------------HCKLHNGINRDSSMTASFIQILLSYKSSITTQASMEFRRKGSQMST 503
Fly 691 ----PNSLNDPQSLPPTLTIDKYESGRAEAIGTLCKIFCAKKTGEEILPVYLARFYMALQQCLKI 751
.|.:.|....| |.||:|||||.||||:|||:|||||||||.||:||||.|.|.|:|
Human 504 DTMVSNPMFDASEFP-----DNYEAGRAEACGTLCRIFCSKKTGEEILPAYLSRFYMLLIQGLQI 563
Fly 752 TESRECDETLASILLHSSDLFRLDLDGINVLLPGFIAALEIVLPDKDLKLKTQSMVFNRTELRRS 816
.: ..|...|||::|:|..||..||.||:|::|.||:|||.:|||::|. |.:|.| |.||||||
Human 564 ND-YVCHPVLASVILNSPPLFCCDLKGIDVVVPYFISALETILPDRELS-KFKSYV-NPTELRRS 625
Fly 817 AINILLSIMVLPLHYQTLPIRDLTCE---------SSEKMFTFIQLKSRLMNILMNALQVETDAQ 872
:||||||::.||.|:.|:. .::..| |.:|..||:.||.||:|||:.|||.|||..
Human 626 SINILLSLLPLPHHFGTVK-SEVVLEGKFSNDDSSSYDKPITFLSLKLRLVNILIGALQTETDPN 689
Fly 873 NTHMLLGGLLLCVQDAVTFE----ETELGGGNANLSQNSSGVQHHDANLLSSACSERSASLVSAG 933
||.|:||.:|..|||:...| :.|:|||..|| :|.|..::|
Human 690 NTQMILGAMLNIVQDSALLEAIGCQMEMGGGENNL---------------------KSHSRTNSG 733
Fly 934 TASLGGQTTATMGAGSGSIRDTASAHDYPSLTISDDMSFEFGQELEGVTTYDNAHALFVRATYLV 998
.:|..| ||...|....:.|:..:..|.:. ..|:|..|.:|:.:||
Human 734 ISSASG----------GSTEPTTPDSERPAQALLRDYAL----------NTDSAAGLLIRSIHLV 778
Fly 999 CHRLISSWKTDLNVSLAALELLSGLARLHIRETDALECKRAVKWICDYICYQCSRPPPAHSKDLH 1063
..||.|.|:.|:::||||||||||||::.:. .|:.:.|||:..:|.||.||||||.|.||:|||
Human 779 TQRLNSQWRQDMSISLAALELLSGLAKVKVM-VDSGDRKRAISSVCTYIVYQCSRPAPLHSRDLH 842
Fly 1064 STIVAAFQCTAAWLMQHPYLLQDKDCLQTVLEVVELGISGTKSQSKGTDIPKFKDEKELKPASMR 1128
|.|||||||...||.:||.:|.:||||:.|||:|||||||:||::...:: |:|.:||..|||||
Human 843 SMIVAAFQCLCVWLTEHPDMLDEKDCLKEVLEIVELGISGSKSKNNEQEV-KYKGDKEPNPASMR 906
Fly 1129 VRDAAENLLTIILEQVGYFPSECGPESISSLLDELALMKHCNSMVPAAAASSEQAIAKFKYFVTE 1193
|:||||..||.|::.:|.|||..||.|..||::|..|:|: |.:|.....| |:|||.:
Human 907 VKDAAEATLTCIMQLLGAFPSPSGPASPCSLVNETTLIKY--SRLPTINKHS------FRYFVLD 963
Fly 1194 NSTILALLEEPLGNDQ-DPQPTVTLLIRGPFGRHAWTMQLRHLPR-SKSGIKYHAINPGRPIPMN 1256
||.|||:||:||||:| |..|:||:|:||..||.||..||..||| :|:..|.....| ||:|.|
Human 964 NSVILAMLEQPLGNEQNDFFPSVTVLVRGMSGRLAWAQQLCLLPRGAKANQKLFVPEP-RPVPKN 1027
Fly 1257 DVTQRLDSEQKNFPDGVDKVQPCVADYSIPTIEQMREQYGTAVIRELESLLENQSIHEKLAWAEA 1321
||..:...:.:.||:.|||:....||.|||.:.:: |..|||.. ||||....|
Human 1028 DVGFKYSVKHRPFPEEVDKIPFVKADLSIPDLHEI-------VTEELEER------HEKLRSGMA 1079
Fly 1322 DTSADSLSHAQ----------------ECVPPTVCHEFHAARLFLSHFGFLGFET-RNPQNPAEA 1369
...|..:...| :|.||....||..|||||||||||..|. :.|.|..
Human 1080 QQIAYEIHLEQQSEEELQKRSFPDPVTDCKPPPPAQEFQTARLFLSHFGFLSLEALKEPANSR-- 1142
Fly 1370 LGNPPQRPLIVLDTKSAAFAADLDRLDKLSARTHDSVYVFYVKSGQTSAQQIIANMGEESSASHD 1434
.||. ||.||:....|..|:..||.|..|..|:|::||:|.||.:.|:|:.|: |||.:..
Human 1143 --LPPH--LIALDSTIPGFFDDIGYLDLLPCRPFDTVFIFYMKPGQKTNQEILKNV--ESSRTVQ 1201
Fly 1435 PHFASMLQTLGWPVQVSEHSGWTGFAHNSWSL------KGTPEEQLKSTAN--ELNYNGSQRVLY 1491
|||...|.:|||.|.|..|.||||....|||: :|:.:|::.|:.: ...:||.::|||
Human 1202 PHFLEFLLSLGWSVDVGRHPGWTGHVSTSWSINCCDDGEGSQQEEVISSEDIGASIFNGQKKVLY 1266
Fly 1492 WADVSSEIAFVVPTTWNLRYNSDTCDSGSISSTDQIGSSNVWTRGEADSAAGLAKSKSRNLSLEL 1556
:||..:|||||||:. :...:|:.:| :.:||...||: |...|:.|..| |:|||
Human 1267 YADALTEIAFVVPSP--VESLTDSLES---NISDQDSDSNM------DLMPGILKQPS--LTLEL 1318
Fly 1557 DTNRRD---VKEPVPPTRRKGNVT--KPTLLAQAPAKIFLVWLESYEDYLNFPLEDLLAYTRTGE 1616
..|..| ..:.:.|:.|...:. :|........::.:||:|.|:|..||||.:|:....||.
Human 1319 FPNHTDNLNSSQRLSPSSRMRKLPQGRPVPPLGPETRVSVVWVERYDDIENFPLSELMTEISTGV 1383
Fly 1617 E--------LQTQQLPRASDCHVIFVHSLLSGLLRVKLQGPPGRMSFATPLVDGMVLSRRVVGNL 1673
| |::..|.: :..|||:|.|.:||.|:|:||..|:.:...||||||::|||.:|.|
Human 1384 ETTANSSTSLRSTTLEK--EVPVIFIHPLNTGLFRIKIQGATGKFNMVIPLVDGMIVSRRALGFL 1446
Fly 1674 VRQTALNISRRRRLDNDNYQPPHVRRRLKVQDIVQKYKMDLSEADLLAHLFQ 1725
||||.:||.||:||::|:|.||||||:.|:.|||.||:....|.:....|||
Human 1447 VRQTVINICRRKRLESDSYSPPHVRRKQKITDIVNKYRNKQLEPEFYTSLFQ 1498
| 
