|
Fly 1 MYSEWASLSAQITANSCGAQCFSVLNKFPASAGREVVVSVVKQLGTNLGITQNAEPSHLVK-DEE 64
|||||.||.. :..|..|.. |||:.:|.|.||||..:||:.||..||.:..|....|:| |:|
Rat 1 MYSEWRSLHL-VIQNDQGHT--SVLHSYPESVGREVANAVVRPLGQALGTSSVAGSESLLKTDKE 62
Fly 65 VKWCMDVICFGLSLPLQEHETIKDCVNVYCEWLTALHPQPRISVPKPICEDANLYARQIINHFHN 129
|||.|:|||:||:||| :.||:|.||:||.:|:.|| ..|:.|:|.|:.::.|||.:.|:.|..|
Rat 63 VKWTMEVICYGLTLPL-DGETVKYCVDVYTDWIMAL-VLPKDSIPLPVIKEPNLYIQSILKHLQN 125
Fly 130 LFVPRQGEILPFLYQTTLGADTIKRQAVLCHRVLRTLQQTAQISQLMDRQTWDTLLLFLLAINEI 194
||||||.: |:..|: ||.:|||.:|:.|:.|.:|.|:||:.||||||.||:|
Rat 126 LFVPRQEQ----------GSSQIR----LCLQVLRAIQKLARESSIMARETWEVLLLFLLQINDI 176
Fly 195 LLAPPTVKDDVGDQLCERVLSVLFEVWLLACVRSFPSPSMWKTLQESCAMWRHRVALVDQWNRVN 259
|||||||:..:.:.|.|:::.||||||||||.|.||:|..|||.:|..|.|||..|:|:||::|.
Rat 177 LLAPPTVQGGIAENLAEKLIGVLFEVWLLACTRCFPTPPYWKTAKEMVANWRHHPAVVEQWSKVI 241
Fly 260 LALTARLLEFSYGPAFPQLKNADEDGQLIPIGMSNDCVAQTWYRFLRMIGNPTALCSPHIISKSS 324
.|||:|||.|:|||:||..|..|||..|||..|.|:|:||||:|||.|:.||..|.:|.:||.:.
Rat 242 CALTSRLLRFTYGPSFPPFKVPDEDANLIPPEMDNECIAQTWFRFLHMLSNPVDLSNPAVISSTP 306
Fly 325 HFVQWALTHEKG--AETHQHPCLQQLPQIFLNAMKGISSQVDAFLGVYQPPPQQTDGVVTNLLEI 387
.| |....:..| .|..|:|||:.|||||..||:|||..||||||:.:|
Rat 307 KF-QEQFLNVSGMPQELSQYPCLKHLPQIFFRAMRGISCLVDAFLGISRP--------------- 355
Fly 388 RHSLNEATSSTLQQFIHSSSATNIANQQNQPAHHHHHLHYPHLHLHGAGSFLRDNFMSNSASSAL 452
.|:||
Rat 356 --------------------------------------------------------RSDSA---- 360
Fly 453 NAIMGHHGGHHGHHHQQQQQQQQQLQISASPTSSLTTSGSSAVGSTSAGGSHSAGVVGSISFGAT 517
..:|.:.|:...|:||.:
Rat 361 ---------------------------PPTPVNRLSMPQSAAVNT-------------------- 378
Fly 518 ESPGPGQASASATPTPPLQRRLAKSFSVAPTITQQKGLSKTSLIGLTGGGARNAISSSSTTTTNA 582
|||..|| ...:|..|...|||.: ||.:.
Rat 379 --------------TPPHNRR-------HRAVTVNKATMKTSTV----------------TTAHT 406
Fly 583 GSTGGTGSGDGSAPAPLPTTPTSTSGPPSASSSINSLPLTSMGAGVELAVARPKCNSILHVFHEW 647
... ....|:.:|| ::|..||..| ..|| |..|||.||||::|..|
Rat 407 SKV----QHQASSTSPL-SSPNQTSSEP------RPLP----------APRRPKVNSILNLFGSW 450
Fly 648 LFEAAHIGGDTWRQNRKKQACE---ASKRPSSMI-------------------MEHRKGSISLSQ 690
||:||.: .|: ...|.|||. ||.|:....:|.
Rat 451 LFDAAFV------------HCKLHNGINRDSSMTASFIQILLSYKSSIATQASMEFRRKGSQMST 503
Fly 691 PNSLNDP----QSLPPTLTIDKYESGRAEAIGTLCKIFCAKKTGEEILPVYLARFYMALQQCLKI 751
...:::| ...| |.||:|||||.||||:|||:|||||||||.||:||||.|.|.|:|
Rat 504 DTMVSNPVFDASEFP-----DNYEAGRAEACGTLCRIFCSKKTGEEILPAYLSRFYMLLIQGLQI 563
Fly 752 TESRECDETLASILLHSSDLFRLDLDGINVLLPGFIAALEIVLPDKDLKLKTQSMVFNRTELRRS 816
.: ..|...|||::|:|..||..||.||:|::|.||:|||.:|||::|. |.:|.| |.||||||
Rat 564 ND-YVCHPVLASVILNSPPLFCCDLKGIDVVVPYFISALETILPDRELS-KFKSYV-NPTELRRS 625
Fly 817 AINILLSIMVLPLHYQTLPIRDLTCE---------SSEKMFTFIQLKSRLMNILMNALQVETDAQ 872
:||||||::.||.|:.|:. .::..| |.:|..||:.||.||:|||:.|||.|||..
Rat 626 SINILLSLLPLPHHFGTVR-SEVVLEGKFSNDDSSSYDKPITFLSLKLRLVNILIGALQTETDPN 689
Fly 873 NTHMLLGGLLLCVQDAVTFE----ETELGGGNANLSQNSSGVQHHDANLLSSACSERSASLVSAG 933
||.|:||.:|..|||:...| :.|:|||..|| :|.|..::|
Rat 690 NTQMILGAMLNIVQDSALLEALGCQMEMGGGENNL---------------------KSHSRTNSG 733
Fly 934 TASLGGQTTATMGAGSGSIRDTASAHDYPSLTISDDMSFEFGQELEGVTTYDNAHALFVRATYLV 998
.:|..| ||...|....:.|:..:..|.:. ..|:|..|.:|:.:||
Rat 734 ISSASG----------GSTEPTTPDSERPAQALLRDYAL----------NTDSAAGLLIRSIHLV 778
Fly 999 CHRLISSWKTDLNVSLAALELLSGLARLHIRETDALECKRAVKWICDYICYQCSRPPPAHSKDLH 1063
..||.|.|:.|:::||||||||||||::.:. .|..:.|||:..:|.||.||||||.|.||:|||
Rat 779 TQRLNSQWRQDMSISLAALELLSGLAKVKVM-VDLGDRKRAISSVCSYIVYQCSRPAPLHSRDLH 842
Fly 1064 STIVAAFQCTAAWLMQHPYLLQDKDCLQTVLEVVELGISGTKSQSKGTDIPKFKDEKELKPASMR 1128
|.|||||||...||.:||.:|.:||||:.|||:|||||||:||::...:: |:|.:||..|||||
Rat 843 SMIVAAFQCLCVWLTEHPDMLDEKDCLKEVLEIVELGISGSKSKNSEQEV-KYKGDKEPNPASMR 906
Fly 1129 VRDAAENLLTIILEQVGYFPSECGPESISSLLDELALMKHCNSMVPAAAASSEQAIAKFKYFVTE 1193
|:||||..||.|::.:|.|||..||.|..||::|..|:|: |.:|.....| |:|||.:
Rat 907 VKDAAEATLTCIMQLLGAFPSPSGPASPCSLVNETTLIKY--SRLPTINKHS------FRYFVLD 963
Fly 1194 NSTILALLEEPLGNDQ-DPQPTVTLLIRGPFGRHAWTMQLRHLPR-SKSGIKYHAINPGRPIPMN 1256
||.|||:||:||||:| |..|:||:|:||..||.||..||..||| :|:..|.....| ||:|.|
Rat 964 NSVILAMLEQPLGNEQNDFFPSVTVLVRGMSGRLAWAQQLCLLPRGAKANQKLFVPEP-RPVPKN 1027
Fly 1257 DVTQRLDSEQKNFPDGVDKVQPCVADYSIPTIEQMREQYGTAVIRELESLLENQSIHEKLAWAEA 1321
||..:...:.:.||:.|||:....||.|||.:.:: |..|||.. ||||....|
Rat 1028 DVGFKYSVKHRPFPEEVDKIPFVKADLSIPDLHEI-------VTEELEER------HEKLRSGMA 1079
Fly 1322 DTSADSLSHAQ----------------ECVPPTVCHEFHAARLFLSHFGFLGFET-RNPQNPAEA 1369
...|..:...| :|.||....||..|||||||||||..|. :.|.|..
Rat 1080 QQIAYEMHLEQQSEGELQKRSFPDPVTDCKPPPPAQEFQTARLFLSHFGFLSLEALKEPANSR-- 1142
Fly 1370 LGNPPQRPLIVLDTKSAAFAADLDRLDKLSARTHDSVYVFYVKSGQTSAQQIIANMGEESSASHD 1434
.||. ||.||:....|..|:..||.|..|..|:|::||:|.||.:.|:|:.|: |||.:..
Rat 1143 --LPPH--LIALDSTIPGFFDDIGYLDLLPCRPFDTVFIFYMKPGQKTNQEILKNV--ESSRNVQ 1201
Fly 1435 PHFASMLQTLGWPVQVSEHSGWTGFAHNSWSLK----GTPEEQLKSTANE----LNYNGSQRVLY 1491
|||...|.:|||.|.|..|.||||....|||:. |...||.:.|::| ..:||.::|||
Rat 1202 PHFLEFLLSLGWSVDVGRHPGWTGHVSTSWSINSCDDGEGSEQDEVTSSEDVGASIFNGQKKVLY 1266
Fly 1492 WADVSSEIAFVVPTTWNLRYNSDTCDSGSISSTDQIGSSNVWTRGEADSAAGLAKSKSRNLSLEL 1556
:||..:|||||||:. :...:|:.:| :.:||...||: |...|:.|... |:|||
Rat 1267 YADALTEIAFVVPSP--VESLTDSLES---NISDQDSDSNM------DLMPGILKQPP--LTLEL 1318
Fly 1557 DTNRRD-------------VKE-----PVPPTRRKGNVTKPTLLAQAPAKIFLVWLESYEDYLNF 1603
..|..| :|: ||||. |..| ::.:||:|.|:|..||
Rat 1319 VPNHTDSLNSSQRLSPSSRMKKLPQGRPVPPL---GPET----------RVSVVWVERYDDIENF 1370
Fly 1604 PLEDLLAYTRTGEE--------LQTQQLPRASDCHVIFVHSLLSGLLRVKLQGPPGRMSFATPLV 1660
||.||:....||.| |::..|.: :..|||:|.|.:||.|:|:||..|:.:...|||
Rat 1371 PLSDLMTEISTGVETTANSSTSLRSTTLEK--EVPVIFIHPLNTGLFRIKIQGATGKFNMVIPLV 1433
Fly 1661 DGMVLSRRVVGNLVRQTALNISRRRRLDNDNYQPPHVRRRLKVQDIVQKYKMDLSEADLLAHLFQ 1725
|||::|||.:|.|||||.:||.||:||::|:|.||||||:.|:.|||.||:....|.:....|||
Rat 1434 DGMIVSRRALGFLVRQTVINICRRKRLESDSYSPPHVRRKQKITDIVNKYRNKQLEPEFYTALFQ 1498
Fly 1726 1725
Rat 1499 1498
| 
