DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment RhoU and RHOBTB1

DIOPT Version :9

Sequence 1:	NP_001036266.1	Gene:	RhoU / 31945	FlyBaseID:	FBgn0083940	Length:	582	Species:	Drosophila melanogaster
Sequence 2:	NP_001229288.1	Gene:	RHOBTB1 / 9886	HGNCID:	18738	Length:	696	Species:	Homo sapiens

Alignment Length:	199	Identity:	71/199 - (35%)
Similarity:	95/199 - (47%)	Gaps:	29/199 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly   392 SIKCVLVGDGAVGKTNLILSYLEN------RFNPEHIPT--ASDIY---------NADVNVNESP 439
            :||||:|||.|||||.||.:...|      :....|:||  |.|.|         :.|| |:|..
Human    14 TIKCVVVGDNAVGKTRLICARACNTTLTQYQLLATHVPTVWAIDQYRVCQEVLERSRDV-VDEVS 77

  Fly   440 VHLTICDTAGQDTLDPLRELCYPDSDVFLLCFSVVKPETFRAIKTKWAP--KFAKTKAALILVGT 502
            |.|.:.||.|....|  |...|..|||.:||||:..|.:...:|:.|.|  |....:..:||||.
Human    78 VSLRLWDTFGDHHKD--RRFAYGRSDVVVLCFSIANPNSLNHVKSMWYPEIKHFCPRTPVILVGC 140

  Fly   503 QADLRTSP-NVLNKLQTNGEEAISYAD------AWDLATTIGAKYIETSSATQDKVKDVFDTAIW 560
            |.|||.:. ..:|:.:......|...|      ..::|..:|..|.|||...|..:|||||.||.
Human   141 QLDLRYADLEAVNRARRPLARPIKRGDILPPEKGREVAKELGLPYYETSVFDQFGIKDVFDNAIR 205

  Fly   561 EGLV 564
            ..|:
Human   206 AALI 209

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
RhoU	NP_001036266.1	Wrch_1	393..562	CDD:133330	70/194 (36%)
RhoU	NP_001036266.1	RHO	395..559	CDD:197554	66/189 (35%)
RHOBTB1	NP_001229288.1	Rho-like	1..210		71/199 (36%)
		RhoBTB	13..207	CDD:133275	70/195 (36%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	327..348
		BTB	<396..455	CDD:197585
		BTB	476..581	CDD:306997
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0393
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900