DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment RhoU and RND2

DIOPT Version :9

Sequence 1:	NP_001036266.1	Gene:	RhoU / 31945	FlyBaseID:	FBgn0083940	Length:	582	Species:	Drosophila melanogaster
Sequence 2:	XP_011523618.1	Gene:	RND2 / 8153	HGNCID:	18315	Length:	234	Species:	Homo sapiens

Alignment Length:	169	Identity:	55/169 - (32%)
Similarity:	92/169 - (54%)	Gaps:	4/169 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly   394 KCVLVGDGAVGKTNLILSYLENRFNPEHIPTASDIYNADVNVNESPVHLTICDTAGQDTLDPLRE 458
            |.|:|||...|||.|:..:.::.:...::||..:.|.|...:::..:.|.:.||:|....|.:|.
Human     9 KIVVVGDAECGKTALLQVFAKDAYPGSYVPTVFENYTASFEIDKRRIELNMWDTSGSSYYDNVRP 73

  Fly   459 LCYPDSDVFLLCFSVVKPETFRAIKTKWAPKFAK--TKAALILVGTQADLRTSPNVLNKLQTNGE 521
            |.|||||..|:||.:.:|||..::..||..:..:  ..|.::|||.:.|:||....|.:|.....
Human    74 LAYPDSDAVLICFDISRPETLDSVLKKWQGETQEFCPNAKVVLVGCKLDMRTDLATLRELSKQRL 138

  Fly   522 EAISYADAWDLATTIGA-KYIETSSATQDK-VKDVFDTA 558
            ..:::.....||..:|| .|:|.||.:.:: |:|||..|
Human   139 IPVTHEQGTVLAKQVGAVSYVECSSRSSERSVRDVFHVA 177

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
RhoU	NP_001036266.1	Wrch_1	393..562	CDD:133330	55/169 (33%)
RhoU	NP_001036266.1	RHO	395..559	CDD:197554	54/168 (32%)
RND2	XP_011523618.1	Rnd2_Rho7	7..227	CDD:206736	55/169 (33%)
RND2	XP_011523618.1	RHO	10..182	CDD:197554	54/168 (32%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0393
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900