DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment RhoU and rac3b

DIOPT Version :9

Sequence 1:	NP_001036266.1	Gene:	RhoU / 31945	FlyBaseID:	FBgn0083940	Length:	582	Species:	Drosophila melanogaster
Sequence 2:	NP_001307335.1	Gene:	rac3b / 795167	ZFINID:	ZDB-GENE-080220-21	Length:	192	Species:	Danio rerio

Alignment Length:	182	Identity:	85/182 - (46%)
Similarity:	114/182 - (62%)	Gaps:	6/182 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly   392 SIKCVLVGDGAVGKTNLILSYLENRFNPEHIPTASDIYNADVNVNESPVHLTICDTAGQDTLDPL 456
            :||||:|||||||||.|::||..|.|..|:|||..|.|:|:|.|:..||:|.:.|||||:..|.|
Zfish     3 AIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDGKPVNLGLWDTAGQEDYDRL 67

  Fly   457 RELCYPDSDVFLLCFSVVKPETFRAIKTKWAPKFAK--TKAALILVGTQADLRTSPNVLNKLQTN 519
            |.|.||.:||||:|||:|.|.:|..::.||.|:...  ....:|||||:.|||...:.:.:|:..
Zfish    68 RPLSYPQTDVFLICFSLVSPASFENVRAKWYPEVRHHCPNTPIILVGTKLDLRDDKDTIERLRDK 132

  Fly   520 GEEAISYADAWDLATTIGA-KYIETSSATQDKVKDVFDTAIWEGLVPTTLPP 570
            ....|:|.....:|..||| ||:|.|:.||..:|.|||.||...|.|   ||
Zfish   133 KLSPITYPQGLAMAREIGAVKYLECSALTQRGLKTVFDEAIRAVLCP---PP 181

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
RhoU	NP_001036266.1	Wrch_1	393..562	CDD:133330	81/171 (47%)
RhoU	NP_001036266.1	RHO	395..559	CDD:197554	77/166 (46%)
rac3b	NP_001307335.1	Rac1_like	3..176	CDD:206663	81/172 (47%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0393
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1091615at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	4	3.820