Protein Alignment RhoU and Rhobtb3

DIOPT Version :10

• Sequence 1: NP_001036266.1
• Gene: RhoU / 31945
• FlyBaseID: FBgn0083940
• Length: 582
• Species: Drosophila melanogaster
• Sequence 2: NP_082769.1
• Gene: Rhobtb3 / 73296
• MGIID: 1920546
• Length: 611
• Species: Mus musculus
• Alignment Length: 306
• Identity: 56/306 - (18%)
• Similarity: 94/306 - (30%)
• Gaps: 115/306 - (37%)

  Fly   291 VALGVGGGPFIFGIAPEQQVTDYGSNPLPPTPPQLKQQSVISRSPLQQSLSDTSAASSGKGSKFL 355
            ||||..|..|.....|...:..|                 :.||||          .||..|..|
Mouse     6 VALGNEGDTFHQDNRPSGLIRTY-----------------LGRSPL----------VSGDESSLL 43

  Fly   356 LRKRKSKKTTAAAAATTEAATTAKKDGKKAIAQPQPSIKCVLVGDGAVGKTNLILSYLENRFNPE 420
            |.           ||:|.|        :....:.|.|         |.|...|::
Mouse    44 LN-----------AASTVA--------RPVFTEYQAS---------AFGNVKLVV---------- 70

  Fly   421 HIPTASDIYNADVNVNESPVHLTICDTAGQDTLDPLRELCYPDSDVFLLCFSVVKPETFRAIKTK 485
            |.....||:::|...:.:.:                     ..:|:.::.::|....:|..:|..
Mouse    71 HDCPVWDIFDSDWYTSRNLI---------------------GGADIIVIKYNVNDKFSFHEVKDN 114

  Fly   486 WAP--KFAKTKAALIL--VGTQADLRTSPNVLNKLQTNGEEAISYADAWDLATTIGAKYIETSS- 545
            :.|  |.|.....:|:  |||:.: ...|.......::....::..:...||..:||.|:|..|
Mouse   115 YIPVIKRASNSVPVIIAAVGTRQN-EELPCTCPLCTSDRGSCVTTTEGIQLAKELGATYLELHSL 178

  Fly   546 -----------------------ATQDKVKDVFDTAIWEGLVPTTL 568
                                   .|.:|:|....|:.:.|:.|..|
Mouse   179 DDFYIGKYFGGVLEYFMIQALNQKTSEKMKKRKMTSSFHGIRPPQL 224

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
RhoU	NP_001036266.1	Wrch_1	393..562	CDD:133330	30/196 (15%)
Rhobtb3	NP_082769.1	Rho-like	1..175		47/255 (18%)
		P-loop containing Nucleoside Triphosphate Hydrolases	34..174	CDD:476819	36/209 (17%)
		BTB1_POZ_RHOBTB3	236..393	CDD:349666
		BTB2_POZ_RHOBTB3	410..519	CDD:349669
		Interaction with Rab9. /evidence=ECO:0000250	420..611
		BACK_RHOBTB3	529..611	CDD:350607