Protein Alignment RhoU and RAC2

DIOPT Version :10

• Sequence 1: NP_001036266.1
• Gene: RhoU / 31945
• FlyBaseID: FBgn0083940
• Length: 582
• Species: Drosophila melanogaster
• Sequence 2: NP_002863.1
• Gene: RAC2 / 5880
• HGNCID: 9802
• Length: 192
• Species: Homo sapiens
• Alignment Length: 192
• Identity: 85/192 - (44%)
• Similarity: 115/192 - (59%)
• Gaps: 8/192 - (4%)

  Fly   392 SIKCVLVGDGAVGKTNLILSYLENRFNPEHIPTASDIYNADVNVNESPVHLTICDTAGQDTLDPL 456
            :||||:|||||||||.|::||..|.|..|:|||..|.|:|:|.|:..||:|.:.|||||:..|.|
Human     3 AIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDSKPVNLGLWDTAGQEDYDRL 67

  Fly   457 RELCYPDSDVFLLCFSVVKPETFRAIKTKWAPKFAK--TKAALILVGTQADLRTSPNVLNKLQTN 519
            |.|.||.:||||:|||:|.|.::..::.||.|:...  ....:|||||:.|||...:.:.||:..
Human    68 RPLSYPQTDVFLICFSLVSPASYENVRAKWFPEVRHHCPSTPIILVGTKLDLRDDKDTIEKLKEK 132

  Fly   520 GEEAISYADAWDLATTI-GAKYIETSSATQDKVKDVFDTAIWEGLVPTTLPPTPSFWRKLFC 580
            ....|:|.....||..| ..||:|.|:.||..:|.|||.||     ...|.|.|:..:|..|
Human   133 KLAPITYPQGLALAKEIDSVKYLECSALTQRGLKTVFDEAI-----RAVLCPQPTRQQKRAC 189

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
RhoU	NP_001036266.1	Wrch_1	393..562	CDD:133330	80/171 (47%)
RAC2	NP_002863.1	Rac1_like	3..176	CDD:206663	80/177 (45%)
		Effector region. /evidence=ECO:0000255	32..40		4/7 (57%)