DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment RhoU and rhobtb3

DIOPT Version :9

Sequence 1:	NP_001036266.1	Gene:	RhoU / 31945	FlyBaseID:	FBgn0083940	Length:	582	Species:	Drosophila melanogaster
Sequence 2:	XP_691270.6	Gene:	rhobtb3 / 562804	ZFINID:	ZDB-GENE-091204-190	Length:	619	Species:	Danio rerio

Alignment Length:	188	Identity:	38/188 - (20%)
Similarity:	69/188 - (36%)	Gaps:	38/188 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly   392 SIKCVLVGD---GAVG-----------KTNLILSYL--------ENRFNPEHIP--TASDIYNAD 432
            |:..|.:|.   |.||           :..|:.|||        .|...|...|  .|...|.:.
Zfish     2 SVHIVALGSECPGGVGPGDETTSSGQIQGGLLWSYLGHGARELDPNSMTPSRHPLNPAFMEYQSR 66

  Fly   433 VNVNESPVHLTICDTAGQDTLD----PLRELCYPDSDVFLLCFSVVKPETFRAIKTKWAPKFAK- 492
            |   ...|.:.:.|....|.||    .:|.: ...:|:.::.:||.....|:.::..:||:...
Zfish    67 V---MGDVRVMVRDCPSWDILDSDWVSVRSI-LEQADIVVIKYSVNDKLAFQQVRNGYAPRLRPL 127

  Fly   493 -----TKAALILVGTQADLRTSPNVLNKLQTNGEEAISYADAWDLATTIGAKYIETSS 545
                 ....|:.||.:.:....|.......::....:.:::...|:..:||.|:|..|
Zfish   128 LRHWGVPVILVAVGARLNDEGPPCTCPLCASDWSSCVPHSEGLQLSRDLGATYLELPS 185

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
RhoU	NP_001036266.1	Wrch_1	393..562	CDD:133330	37/187 (20%)
RhoU	NP_001036266.1	RHO	395..559	CDD:197554	37/185 (20%)
rhobtb3	XP_691270.6	P-loop_NTPase	<97..189	CDD:304359	16/89 (18%)
		BTB	254..>296	CDD:295341
		BTB	417..518	CDD:279045
		BTB	428..518	CDD:197585
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0393
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900