DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment RhoU and RND3

DIOPT Version :9

Sequence 1:	NP_001036266.1	Gene:	RhoU / 31945	FlyBaseID:	FBgn0083940	Length:	582	Species:	Drosophila melanogaster
Sequence 2:	NP_001241667.1	Gene:	RND3 / 390	HGNCID:	671	Length:	244	Species:	Homo sapiens

Alignment Length:	189	Identity:	64/189 - (33%)
Similarity:	108/189 - (57%)	Gaps:	10/189 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly   378 AKKDGKKAIAQPQPSIKC--VLVGDGAVGKTNLILSYLENRFNPEHIPTASDIYNADVNVNESPV 440
            ::|...|:|..|..::||  |:|||...|||.|:..:.::.|...::||..:.|.|...::...:
Human     7 SQKLSSKSIMDPNQNVKCKIVVVGDSQCGKTALLHVFAKDCFPENYVPTVFENYTASFEIDTQRI 71

  Fly   441 HLTICDTAGQDTLDPLRELCYPDSDVFLLCFSVVKPETFRAIKTKWAPKFAK----TKAALILVG 501
            .|::.||:|....|.:|.|.|||||..|:||.:.:|||..::..||..:..:    ||  ::|||
Human    72 ELSLWDTSGSPYYDNVRPLSYPDSDAVLICFDISRPETLDSVLKKWKGEIQEFCPNTK--MLLVG 134

  Fly   502 TQADLRTSPNVLNKLQTNGEEAISYADAWDLATTIG-AKYIETSS-ATQDKVKDVFDTA 558
            .::||||..:.|.:|..:.:..:||....::|..|| |.|||.|: .:::.|:|:|..|
Human   135 CKSDLRTDVSTLVELSNHRQTPVSYDQGANMAKQIGAATYIECSALQSENSVRDIFHVA 193

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
RhoU	NP_001036266.1	Wrch_1	393..562	CDD:133330	60/174 (34%)
RhoU	NP_001036266.1	RHO	395..559	CDD:197554	59/172 (34%)
RND3	NP_001241667.1	Rnd3_RhoE_Rho8	19..200	CDD:206735	60/177 (34%)
RND3	NP_001241667.1	Effector region. /evidence=ECO:0000255	52..60		2/7 (29%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0393
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810