DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment RhoU and RHOQ

DIOPT Version :9

Sequence 1:	NP_001036266.1	Gene:	RhoU / 31945	FlyBaseID:	FBgn0083940	Length:	582	Species:	Drosophila melanogaster
Sequence 2:	NP_036381.2	Gene:	RHOQ / 23433	HGNCID:	17736	Length:	205	Species:	Homo sapiens

Alignment Length:	176	Identity:	79/176 - (44%)
Similarity:	103/176 - (58%)	Gaps:	3/176 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly   393 IKCVLVGDGAVGKTNLILSYLENRFNPEHIPTASDIYNADVNVNESPVHLTICDTAGQDTLDPLR 457
            :|||:|||||||||.|::||..:.|..|::||..|.|...|.|......|.:.|||||:..|.||
Human    10 LKCVVVGDGAVGKTCLLMSYANDAFPEEYVPTVFDHYAVSVTVGGKQYLLGLYDTAGQEDYDRLR 74

  Fly   458 ELCYPDSDVFLLCFSVVKPETFRAIKTKWAPKFAK--TKAALILVGTQADLRTSPNVLNKLQTNG 520
            .|.||.:||||:|||||.|.:|:.:|.:|.|:..:  .....:|:|||.|||..|..|.:|....
Human    75 PLSYPMTDVFLICFSVVNPASFQNVKEEWVPELKEYAPNVPFLLIGTQIDLRDDPKTLARLNDMK 139

  Fly   521 EEAISYADAWDLATTIGA-KYIETSSATQDKVKDVFDTAIWEGLVP 565
            |:.|.......||..||| .|:|.|:.||..:|.|||.||...|.|
Human   140 EKPICVEQGQKLAKEIGACCYVECSALTQKGLKTVFDEAIIAILTP 185

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
RhoU	NP_001036266.1	Wrch_1	393..562	CDD:133330	77/171 (45%)
RhoU	NP_001036266.1	RHO	395..559	CDD:197554	74/166 (45%)
RHOQ	NP_036381.2	Tc10	10..183	CDD:206707	77/172 (45%)
RHOQ	NP_036381.2	Effector region. /evidence=ECO:0000250	38..46		3/7 (43%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0393
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1091615at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.820