DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment RhoU and Rnd1

DIOPT Version :9

Sequence 1:	NP_001036266.1	Gene:	RhoU / 31945	FlyBaseID:	FBgn0083940	Length:	582	Species:	Drosophila melanogaster
Sequence 2:	NP_766200.1	Gene:	Rnd1 / 223881	MGIID:	2444878	Length:	232	Species:	Mus musculus

Alignment Length:	177	Identity:	60/177 - (33%)
Similarity:	93/177 - (52%)	Gaps:	7/177 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly   389 PQPSI---KCVLVGDGAVGKTNLILSYLENRFNPEHIPTASDIYNADVNVNESPVHLTICDTAGQ 450
            |||.:   |.|||||...|||.::....::.:...::||..:.|.|.:...|..|.|::.||:|.
Mouse     7 PQPVVVRCKLVLVGDVQCGKTAMLQVLAKDCYPETYVPTVFENYTACLETEEQRVELSLWDTSGS 71

  Fly   451 DTLDPLRELCYPDSDVFLLCFSVVKPETFRAIKTKWAPKFAK--TKAALILVGTQADLRTSPNVL 513
            ...|.:|.|||.|||..||||.:.:|||..:...||..:...  ....::|:|.:.||||..:.|
Mouse    72 PYYDNVRPLCYSDSDAVLLCFDISRPETMDSALKKWRTEILDYCPSTRVLLIGCKTDLRTDLSTL 136

  Fly   514 NKLQTNGEEAISYADAWDLATTIGAK-YIETSSATQD-KVKDVFDTA 558
            .:|....:..|||.....:|..:||: |:|.|:.|.: .:..:|.||
Mouse   137 MELSHQKQAPISYEQGCAIAKQLGAEIYLEGSAFTSETSIHSIFRTA 183

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
RhoU	NP_001036266.1	Wrch_1	393..562	CDD:133330	57/173 (33%)
RhoU	NP_001036266.1	RHO	395..559	CDD:197554	56/168 (33%)
Rnd1	NP_766200.1	P-loop_NTPase	1..232	CDD:304359	60/177 (34%)
		RHO	16..190	CDD:197554	56/168 (33%)
		Effector region. /evidence=ECO:0000255	42..50		2/7 (29%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0393
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900