DRSC/TRiP Functional Genomics Resources

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Protein Alignment Naxe and edc3

DIOPT Version :10

Sequence 1:NP_572604.2 Gene:Naxe / 31944 FlyBaseID:FBgn0030178 Length:230 Species:Drosophila melanogaster
Sequence 2:NP_001018136.3 Gene:edc3 / 504054 ZFINID:ZDB-GENE-050522-287 Length:506 Species:Danio rerio


Alignment Length:224 Identity:49/224 - (21%)
Similarity:86/224 - (38%) Gaps:59/224 - (26%)


- Green bases have known domain annotations that are detailed below.


  Fly    25 SVDQLMELAGLSCAHAVA--------KCFPAEKH--PRILVCCGPGNNGGDGLVAARHLALMGYT 79
            |:::.:|:.|: ||..:|        :..|...|  |.:.:.|||...|..|:...||||  .:.
Zfish   298 SLERRLEMTGV-CASQMALTLLGGPNRLTPKNVHQRPTVALLCGPHVQGAQGISCGRHLA--NHE 359

  Fly    80 PTIYYPKPTAKPLFENLSHQCQQMD------ICDVKECPSVESAARDYDLILDAL----FGFSFK 134
            ..:....|....:.|.::.:.....      :.:||:.|..     ..||:::.|    .||...
Zfish   360 VEVVLFLPNFVKMLEAITSELALFGKTGGRLVSNVKDLPGT-----PVDLVINCLDSHENGFLRD 419

  Fly   135 PPVRADFVAVVELMQQTKLPIASVDIP-SG--------WDVEKG---KLTE-------CDVEPAL 180
            .|.   :.|..:...|.:.|:.|:|.| ||        |.:..|   .|:|       ||:    
Zfish   420 QPW---YKAAADWANQNRAPVLSIDPPVSGQAHAVEAKWSLSLGLPLPLSEGAGRVYLCDI---- 477

  Fly   181 LISLTAPKLCARQFRGEHHY-LGGRFVPP 208
                ..|:...::...::|. .|.:||.|
Zfish   478 ----GIPRQVFQEVGIKYHSPFGCKFVIP 502

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
NaxeNP_572604.2 PLN03049 3..>230 CDD:215550 49/224 (22%)
edc3NP_001018136.3 Required for P-body targeting and interaction with DCP1A. /evidence=ECO:0000250 1..77
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 153..181
Required for interaction with DDX6. /evidence=ECO:0000250 187..294
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 219..247
Blue background indicates that the domain is not in the aligned region.

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