|
Fly 8 AAAVA-PTAALPPQPSVPPPLPDAPPP-----PPPSDATAGAGASSGASAPIVTTAAAVTTAPGF 66
|:.|| |.|| .:|.:|||..:|||| |...|:.....:...|....:...||...|...
Mouse 337 ASQVAEPLAA--EKPPLPPPNEEAPPPLSPEEPQSEDSEDSEDSEEDARFKQLKAIAAHWQAAAA 399
Fly 67 NPYSSGQATGAGNPYQ---------QYTAAQYAAM---TPE---------------QQYALQHHW 104
: :...|....|..|| |....||..: :|. ||...||.:
Mouse 400 H-WQQQQQQRVGFQYQGIMQRHTQLQQILQQYQQVIQHSPHIQTMSLDVQLRHYEMQQQQFQHLF 463
Fly 105 QQWQTYQEEYAKWHAQ------------YGEQYKREMAAAAATTTAVQ----------------- 140
|.| :.|:..|..| |.:|:|.......||.|.:|
Mouse 464 QDW---EREFQLWEEQLHSYPHKDQLQEYEKQWKTWQGHMKATQTYLQEKVNSFQTVKSQYLGNM 525
Fly 141 GVPAPVV---------------ATPAAAPVPV--------VAPPG------PQAYPVA---HNYY 173
.:|.|.| ..|.:.|.|| :.||| |.:.|.: ....
Mouse 526 AMPPPFVPYSQMPPPLPTMPPPVLPPSLPPPVMPPALPTSIPPPGMPPPVMPPSLPTSVPPPGMP 590
Fly 174 QGVSASPAQSTTPVAV--AGAPP------LPG--KIMAQPQMYNQPPPP--PQKGGYNQHPNDIQ 226
..:|:.|.....|.|: ||:|| ||| .|:..|.:.:..||| |..|. | |
Mouse 591 PSLSSGPPPVLPPPALSSAGSPPVLPPPALPGGPPILPLPPLSSATPPPGIPPPGA----P---Q 648
Fly 227 SMWSGPPPMQQPPPNRYGGGQMNQMNYNIAGQDNQGFPNLQQP------PPSLQRPTPQQQQPHL 285
.| ||.:..|.|...| ..|..|..:..|.. |..| |||...|.||.:| :
Mouse 649 GM---PPQLTAPLPPASG-----SQNSQIPEKPRQAL--LPTPVSFGSTPPSPYHPPPQSEQ--V 701
Fly 286 NHMDHGQWGNNQHGVGNNN---------RPTWDTSG----PPPDNT----GQPNRWNGPPPANDV 333
|.....:..:::.|:|.:: :.|...|| .||..: .:..|::||....|:
Mouse 702 NSKPLNKVFSSEQGLGESSALSQSIIAAKDTPVKSGGLLADPPKGSFLEGPRGPRFDGPRRFEDL 766
Fly 334 NNRW-----NGTSFNNNTNDGNR-------------RWDGTSNQAPSG-----GDQQLNRWMSEP 375
.:|. .|..|..|..||.| :| ||..:.|:. .:..|:...|.|
Mouse 767 GSRCEGPRPKGPRFEGNRPDGPRPRYESHPAEGTKSKW-GTIPRGPASQFYITPNTSLSPRQSGP 830
Fly 376 PPSLP----------NPNQQYQNQNSWMSGPPPSISDPPQDHQQQNNSSQNA------------- 417
....| .|.||.::|...:||....::| ..::||:|...|:|
Mouse 831 QWKGPKATVGQQHQQQPKQQPKSQAEPLSGNKEPLAD-TSNNQQKNLKIQSAAFSISADVKDTKA 894
Fly 418 ------------------------RSSRW----QGINSDID-----TPPMRTNNKPNSIQN---S 446
..|.| |.:.:::| |.|:...|||...|: |
Mouse 895 AQSNENLSDSQQEPTKSQVSEGPVEPSNWNQNSQSMETEMDKAEGVTQPVSLANKPVPTQSTFPS 959
Fly 447 RNSWGDGG--------------GDG-NQSKNPFIKN-PQSDFGNYGNSYNSQDQGSAG-GGNFGG 494
:....:|| |.| :.|:|...|: ||.| |..::.:|:.| ..::.|
Mouse 960 KVGSMEGGAAAAALTADDFKPLGVGLSHSENHQEKDLPQPD------SRENRLEGNKGSSSSYRG 1018
Fly 495 FGDDSGGKQSQDSFAGRG------GGPGNNINNNFSN---NRRQNNRRDNNRNQGFSDE---RGG 547
.|.:...:........|| .|||.....:|.: .||:::|...||.:|..|. |.|
Mouse 1019 PGQNRVEESRDKGLVNRGRGQIINRGPGLVKQEDFHDKMMGRREDSREKMNRGEGNRDRVFVRPG 1083
Fly 548 G--DSGPGGYNPNRGNYNQRNSFNQSNAPYKQSQQNRNQQQPPDLDEASFDLLFDQWEQQFEEWK 610
. |..|||...: :.|:.|..::.||
Mouse 1084 SSRDKIPGGLQDS-----------------QDSRANSRERGPP---------------------- 1109
Fly 611 LANANHPDRDEYRRYEEEFEKQRRRIAERREQMRRRRQLQMGGSAGGSTTDIRKEAAAGASTTAE 675
..|...:|...|| ...|.|:..:|...|.|...:..|| :|...|
Mouse 1110 -RRAGSQERGPPRR-----AGSRERVPPQRAGSRERVPPRGPGS---------RERGLG------ 1153
Fly 676 QKP----NKDPFEGQGRFADQGD------QDHGSGPNFGNGNRQSGNAGHFGKENRPFESAGVPA 730
:| ::.||..: ..|.|| :|..|..::.:|..: |.|..|.:....|.
Mouse 1154 -RPDFGHDRVPFRSE--LGDGGDKVYPYHRDEPSRASWNHGEER-------GHEEFPVDGRNAPI 1208
Fly 731 FRGN-------------------------------QGPPPGMHN------------QYQTAQEAI 752
.|.. ..||...|: :.|...|..
Mouse 1209 ERERLDDWDRKRYWRECERDYQDDTLDSYSREDRFSAPPSRSHDGDRRGPWWDDWERDQDMDEGY 1273
Fly 753 QQILDEQPDESNQEIPTKPAASNENSSDVKKAKTTASPVAPPIA-------PVVPPEVKAPAAPV 810
.:.:|...|.....| .:|....:.:.|.:..:....|:....: |.:||
Mouse 1274 GREMDRDLDRDVDRI-RRPLDIYDRNVDNEWDRDYGRPLDEQESQFRERDIPSLPP--------- 1328
Fly 811 VPDPTVVPPTQPPPVSTNYGKRRQRAAPSQIPAKQVKEEEPIFTISLDDDDDDDEEKEVVQDAPN 875
:||..|.|....|...|.| ||.......|.|..|..|.. :::.|.
Mouse 1329 ------LPPLPPLPPLDRYRDDRWR-------------EERNRDHGYDRDFRDRGELR-IREYPE 1373
Fly 876 TPMGSIFK-KNDGIPGLDLVD------------DGSNKNNSSSVFNVVLKDSSEKKAADETEKQP 927
.|..:: |.|.:| |.:| ...::::..:........|||...:|
Mouse 1374 --RGDTWREKRDYVP--DRMDWERERLSDRWYPSDVDRHSPMAEHMPSSHHSSEMMGSD------ 1428
Fly 928 GDVSADKKGDESLSNALKDPNFINNLSQAVANVQEREQRDRHEQRDDQESGTDGRPLSFAEWQRK 992
|:...|:.|...:. |||....:..:..::....|:.:| :.|:.
Mouse 1429 ----ANLDSDQGLGGVMV-------LSQRQHEIILKAAQELKMLREQKE-----------QLQKL 1471
Fly 993 KNSGNENKSQD---AGDSVSTNNGEKPDNNGPPGGFGPGNGPGGGPGSGPGQNDGSRFDVFGPNQ 1054
|:.|:|.:..| ..|| ...|..:|....|||.:.|
Mouse 1472 KDFGSEPQMADHLPPPDS-RLQNPSRPGMYPPPGSYRP--------------------------- 1508
Fly 1055 VSGNNFIDLDNNGPPGFG-PPGRNFGPNGPGPRGNFGPNFGHNFGPRGPGGPFIRPNGPLPGPGP 1118
||..| |||....|:.|..|.:. |..||..|:|.|.|
Mouse 1509 -------------PPPMGKPPGSIVRPSAPPARSSI---------------PMTRPPVPIPPPPP 1545
Fly 1119 NFGPHFRPNGPNFGPNFGPNFGPRPGSRNFGPRGPDGPFG--PGRDDFGGPPFGGPRPHMGPNGP 1181
|..| .|...|....:..|........|..|| ...||
Mouse 1546 -------PPPP--PPPPPPVIKSKTSSVKQERWDEDSFFGLWDTNDD------------------ 1583
Fly 1182 GHNMRGFNGGPISDNPFRRQGG--------PPGPGFGNDDLGAGPPRGPRNFGNRFGNPGGGGGG 1238
:|.| :.|:|... ||.|...:. ||.||
Mouse 1584 ----QGLN------SEFKRDTATIPSAPVLPPPPVHSSI-----PPPGP---------------- 1617
Fly 1239 GGGGGNNNRKNWNDGPEQQQFHDRLNHNDAIYRPLKVFDYSNNPTAAKVIDYGHKSGDGNPIDGP 1303
.|:.:...|..|.....:|||| |...|
Mouse 1618 --------------------------------MPMGMPPMSKPPPVQHTVDYGH--GRDMP---- 1644
Fly 1304 SGSNPDDRIPEFKAMKTFEYGHSSYMGSNRLGMPGGMGGGGDH-NQAMTGGRGMAAGPGRFGGPG 1367
:|..::|| ||....:..:.| |.......|| .|.....|.....| .|..|.
Mouse 1645 --TNKVEQIP---------YGERITLRPDPL--PERSTFDADHAGQRDRYDRDRDREP-YFDRPS 1695
Fly 1368 GAGNKR---KNKKKNKQQKNGELMTFNQNQQMQSNTVEERSITNPEQDEEQRAHNELRNQNQADE 1429
...:.| ::::.::.:....::.:.::: .|.|:|..:: |||:..|:
Mouse 1696 NITDHRDFKRDRETHRDRDRDRVLDYERDR----------------FDRERRPRDD-RNQSYRDK 1743
Fly 1430 FQKNEERNDLEDISEGEDNLQSIVFD----DDNEELPP---PPSMKIWNQGNAQEQYNPFPVNPL 1487
...:..|.. .|| |...:.|| ||.. |..:..|.
Mouse 1744 KDHSSSRRG--------------GFDRPSYDRKSDRPPYEGPPMF-----GGERRTYP------- 1782
Fly 1488 RRQLGDYSDKLEAPSPAMSLFPSAANANDRTSDPMKASNLEMCVATSENRNTFSLDEVLLYPGRL 1552
.:::..|:||:. ..|.....:| ...|::| :|::|..|||.
Mouse 1783 -------EERMPLPAPALG------------HQPPPVPRVE---KKPESKN---VDDILKPPGRE 1822
Fly 1553 NRPKRICIILRGPPGCGKSHVARLIKEKELEMGGANPRILSIDDYFLIENDYDEKCPKTGKKIPK 1617
:||:||.:|:||.||.||:|||:||::||:|.||..||:||:||||:.|.:.:||.|.:|||:.|
Mouse 1823 SRPERIVVIMRGLPGSGKTHVAKLIRDKEVEFGGPAPRVLSLDDYFIAEVEKEEKDPDSGKKVKK 1887
Fly 1618 KEILYEYDDTMEETYMQYLIKSFKKTLSDNLYDFVIVDCNNNSLRTLNEFYCHAKDSNFVPYIVD 1682
|.:.|||:..|||||...:.|:|||||.|..:.|:|:|..|:.:|..::|:..||...|..|:.:
Mouse 1888 KVMEYEYEADMEETYRTSMFKTFKKTLDDGFFPFIILDAINDRVRHFDQFWSAAKTKGFEVYLAE 1952
Fly 1683 LHCDLETCLGRNSHQRSVNDIRVVLDNWCQTPTHYIKLDVSSLLENV----VEMEDVEDMATDDN 1743
:..|.:||..||.|.|.:.:|..:.::|...|.|.::||:.|||::. |||||.:
Mouse 1953 MSADNQTCGKRNIHGRKLKEINKMAEHWEVAPRHMMRLDIRSLLQDAAIEEVEMEDFD------- 2010
Fly 1744 ACADVGATVGESAALEDAAVEETDDSNSADASNYCGFL-KSKWERDTTEDNLARLDGTKRLMQNR 1807
|.:||...|:.| :.:..:..|:: |||||.||:|..|.:|||.:...:.:
Mouse 2011 ------------ANIEDQKEEKKD---AEEEESELGYIPKSKWEMDTSEAKLDKLDGLRTGTKRK 2060
Fly 1808 R-----TTSMADYLQLEDWKPPTTSDNGKKRVRWADIEEKRSQKKMRAIGFVVGQTDWNRMMDPN 1867
| .:.|.|||||.|......|:.|||||||||:|||:...:.||||||||||||.::.|.:
Mouse 2061 RDWEAIASRMEDYLQLPDDYETRASEPGKKRVRWADLEEKKDADRKRAIGFVVGQTDWEKITDES 2125
Fly 1868 A--GSRALNKTKFI 1879
. ..||||:||:|
Mouse 2126 GHLAERALNRTKYI 2139
| 
