Protein Alignment ZAP3 and ylpm1

DIOPT Version :10

• Sequence 1: NP_001245607.1
• Gene: ZAP3 / 31942
• FlyBaseID: FBgn0052685
• Length: 1885
• Species: Drosophila melanogaster
• Sequence 2: XP_005170211.2
• Gene: ylpm1 / 561348
• ZFINID: ZDB-GENE-030131-2196
• Length: 1850
• Species: Danio rerio
• Alignment Length: 2330
• Identity: 492/2330 - (21%)
• Similarity: 719/2330 - (30%)
• Gaps: 973/2330 - (41%)

  Fly    15 AALPPQP-SVPPPLPDAPPPPPPSDATAGAGASSGASAPIVTTAAAVTTAPGFNPYSSGQATGAG 78
            ||.||.| :.|||.|...|||       |.|..:|..            ||.|.|
Zfish    27 AAQPPPPTTAPPPQPAGAPPP-------GGGGFAGYG------------APSFPP---------- 62

  Fly    79 NPYQQYTAAQYAAMTPEQQYALQHHWQQWQTYQEEYAK-------------------WHAQYGEQ 124
                    :.::::.       :.|.||.|..|:.:.|                   |.|
Zfish    63 --------SNFSSLH-------EQHLQQMQQLQQLHQKQLQSVLHHSGNNSNSPSPYWQA----- 107

  Fly   125 YKREMAAAAATTTAVQGV-PAPVVATPAAAPVPVVAPPGPQAYPVAHNYYQGVSASPAQSTTPVA 188
               ..|..||...:.|.. |.|      ..|.|.|.||.|:..|.|    ...|..||.||..|:
Zfish   108 ---GGAGPAAPPNSFQAAGPQP------QPPPPEVKPPAPEPPPPA----PAASKPPAASTPQVS 159

  Fly   189 VAGAP-----PLPGKIMAQPQMYNQPPPPPQKGGYNQHPNDIQSMWSGPPPMQQPPPNRYGGGQM 248
            .|.||     |...|:..|.|         |:..|.||..::|.:
Zfish   160 DASAPVGDEKPDFSKMSMQEQ---------QEYWYQQHLQNLQKL-------------------- 195

  Fly   249 NQMNYNIAGQDNQGFPN---LQQPPPSLQRPTPQQQQPHLNHMDHGQWGNNQHGVGNNNRPTWDT 310
                .|...:.|||..|   ...|||.::.|                                 .
Zfish   196 ----KNEKAKQNQGSFNESHASAPPPPVEPP---------------------------------K 223

  Fly   311 SGPPPDNTGQPNRWNGPPPANDVNNRWNGTSFNNNTNDGNRRWDGTSNQAPSGGDQQLNRWMSEP 375
            |.|||           |||                                           .|.
Zfish   224 STPPP-----------PPP-------------------------------------------KEE 234

  Fly   376 PPSLPNPNQQYQNQNSWMSGPPPSISDPPQDHQQQ--NNSSQNARSSRWQGINSDIDTPPMRTNN 438
            ||                  |||    ||.:.|..  ||:...|.::|.|
Zfish   235 PP------------------PPP----PPDESQSSSVNNTGDPAEAARLQ--------------- 262

  Fly   439 KPNSIQNSRNSWGDGGGDGNQSKNPFIKNPQSDFGNYGNSYNSQDQGSAGGGNFGGFGDDSGGKQ 503
               .:|.:...|                                                   :|
Zfish   263 ---QLQVAAAQW---------------------------------------------------QQ 273

  Fly   504 SQDSFAGRGGGPGNNINNNFSNNRRQNNRRDNNRNQGFSDERGGGDSGPGGYNPNRGNYNQRNSF 568
            .|                                                         :||.||
Zfish   274 VQ---------------------------------------------------------HQRASF 281

  Fly   569 N-----QSNAPYKQSQQNRNQ--QQPPDLDEASFDL--------------LFDQWEQQFEEWKLA 612
            .     |.:|..:|..|...|  |||..|....|::              |:.:||:.|..|...
Zfish   282 QYQALMQEHAQLQQILQQYQQVIQQPAHLQTMPFEMQLQHYEMQQQRFAPLYQEWERHFNLWLEQ 346

  Fly   613 NANHPDRDEYRRYEEEF----EKQRRRIAERREQMRRRRQLQ--------MGGSAGGSTTDIR-- 663
            ...:|.:|:...||.::    |:.....|..:|::...|.:|        |.||.|..:.:::
Zfish   347 FQMYPHKDQLHDYEAQWRQWQEQMNSTSAHLQERVTTLRAMQHQYGSSYGMMGSYGQQSPNVQMG 411

  Fly   664 --------------------KEAAAGASTTAEQKPNKD-PFEGQGRFADQ--------------- 692
                                .:|....||   |.|::. |...||.....
Zfish   412 PNGNMNLVGPGTPSMPPPVTMDAMPAPST---QGPSQSGPVVPQGHSPSDLESISETCKTGLPPG 473

  Fly   693 ---------------------------------------------GDQDHGSGPNFGN---GNRQ 709
                                                         |....|:||..|.   |.|.
Zfish   474 HGVRPPGPGVRPPGPGVRPPGPGVRPPGPGVRPPGPGVRPPGPGVGPPGPGAGPGVGQPRPGVRP 538

  Fly   710 SG-NAGHFGKEN-RPFESAGVPAFRG--NQGP---PPGMHNQY-----------QTAQEAIQQIL 756
            .| ..|..|.:. ||:...|.|...|  ..||   |||.|.::           |..|...|:..
Zfish   539 PGPGVGPPGPQGVRPYGPGGRPPGPGVRPSGPGSGPPGPHGRFDGPRFEGPRGPQFEQPPQQRFS 603

  Fly   757 D----------EQPDESNQEIPTKPAASNENSSDVKKAKTTASPVAPPIA-----------PVVP 800
            .          .||...|...|..||.. ||.   .:..|......||:|           ||..
Zfish   604 GPPRFDAGQRFSQPPRGNPPFPGAPARL-ENP---PRQNTPTRFERPPVASQQTGSGQQSSPVTG 664

  Fly   801 PEVKAPAAPVVPDPTVVPP--TQP----PPVSTNYGKRRQRAAPSQI---------------PAK 844
            .:.|..:|.  |:...|||  |.|    .|:|.:..|....:|||..               |..
Zfish   665 NQTKQQSAK--PEAKPVPPSYTDPDKAKSPLSQSTQKENNSSAPSMTDDLVDSVDGFFIQSGPIP 727

  Fly   845 QVKEEEPIFTISLDDDDDDDEEKEVVQDAPNTPMGSIFKKNDGIPGLDLVDDGSNKNN------S 903
            |.|:.:     ..|.|....::.:.|...|:.|..:              .|.:|||:      :
Zfish   728 QTKDSD-----KTDADSAKQDKTKEVTTKPSAPTDA--------------PDTTNKNSNLQPPKT 773

  Fly   904 SSVFN---VVLKDSSEKKAADETEKQP--------------------GDV------SADKKGDES 939
            |...|   ..:|....|...|..::.|                    |.:      ....:|...
Zfish   774 SHTANGPPQQVKPPQNKFKPDTPKETPRMLPMMNQQVPPQMARGRGRGQIPMPLRGRGRARGRGQ 838

  Fly   940 LSNALKDPNFINNLS------QAVANVQEREQRDR--------HEQRDDQESGTDGRPLSFAEWQ 990
            ....:.||||...:.      |...|....|.:||        ..:..|||:     ||..  ||
Zfish   839 YGGPMADPNFQREIEEDSYDHQEPGNASHGEDQDRIWRDPSLDGPEEIDQEA-----PLEI--WQ 896

  Fly   991 RKKNSGNENKSQDAGDSVSTNNGEKPDN-----------------NGPPGGFGPGNGPGGGPGSG 1038
            .::....|...:|...  ..|..|:|.:                 ..||       .|.|||...
Zfish   897 PEEEHFPEEYPEDTHQ--DENWEEEPQDYWEEEDPYWAEQRPAMRARPP-------FPPGGPRRP 952

  Fly  1039 PGQNDGSRFDVFGPNQVSGNNFIDLDNNGPPGFGPPG-------RNFGPNGPGPRGNF------G 1090
            |..   .||.:.||.:......:..:..|||.|.|.|       |..||.||.||.:.      .
Zfish   953 PFH---PRFMLQGPRRPPPPGSLQHNPLGPPPFRPRGGVVPRFRRGLGPWGPLPRHDMMERDLRR 1014

  Fly  1091 PNFGHNFGPRGPGGPF-------IRPNGPLP-GPG---PNFGPHFRPNGPNFGPNFGPNFGPRPG 1144
            |...|....|.|.||.       ..|..|.| |.|   |...||....|..           ||.
Zfish  1015 PPAPHEIIAREPAGPHGYEEEIDREPAWPHPRGRGIRRPPLPPHEMGRGIR-----------RPP 1068

  Fly  1145 SRNFGPR----GP----------DGPFGPGRDDFGGPP-------------------FGGPRPHM 1176
            .|...||    ||          :.|:|...|.:..||                   :.|.:|..
Zfish  1069 MRPAMPRERWHGPPPHEEENYEEEYPYGAEDDVYRRPPHEYNEDYEHGDEYYGSREEWDGEQPER 1133

  Fly  1177 G--PNGPGHNM----------RGFNGGPISDNPFRRQGGPPGPGFGNDDLGAGPPRGPRNFGNRF 1229
            .  |:.|...:          |.|   |..::.:|.:...|   |..||    ||...|:....|
Zfish  1134 DYPPHRPPERVREDPWLEERERSF---PYEEDRYREERRGP---FYPDD----PPYQDRDREPPF 1188

  Fly  1230 GNPGGGGGGGGGGGNNNRKNWN----DGPEQQQFHDRLNHND---------------AIYRPLKV 1275
                           ::|.:|.    ..|.::.:...|:..|               |...||.
Zfish  1189 ---------------HSRSDWERPPPPPPPERGYSRSLSETDYEHKLDPLASLPAPQATDSPLD- 1237

  Fly  1276 FDYSNNPTAAKVI--------------------------------DYGHKSGDGNPIDGPSGSNP 1308
               .::|:|.|.:                                :.......|.|.:.|:|...
Zfish  1238 ---ESSPSATKAVLALSQRQHEIILKAAQELKMIRELQETKKALGEVSTTESAGLPSELPAGILG 1299

  Fly  1309 DDRIPEFKAM-----------KTFEYGHSSYMGSNRLGMPG--------------GMGGGGDHNQ 1348
            .:..||.|:.           :||..|.||...::.|....              |..||....:
Zfish  1300 LEIPPEVKSALQATNLLSETGQTFNAGLSSNQSTDFLSSTAPTASFIAKTVDYAHGRDGGSTVER 1364

  Fly  1349 AMTGGRGMAAGPGRFGGPGGAGNKRKNKKK-------NKQQKNGELMTFNQNQQMQSNTVEERSI 1406
            ...|.|.:..       |..|.::|..:|:       ...:::......:.:::.:.:...|:..
Zfish  1365 ISYGERVLLR-------PAPAPSERSYEKELLGHRDPYYDRRSDPYAARDYDREWERDPYREKPT 1422

  Fly  1407 TNPEQD----------------------EEQRAHN-------ELRNQNQADEFQKNEERNDLEDI 1442
            .:.|:|                      |.:|.|:       ||.|:   ..::::.....||..
Zfish  1423 LDYERDRYERDRYLRDERASLGPRPTYREREREHSSRSSRDRELYNR---PSYERSSYERSLEHY 1484

  Fly  1443 SEGEDNL-QSIVFDDDNEELPPPPSMKIWNQGNAQEQYNPFPVNPLRRQLGDYSDKLEAPSPAMS 1506
            ..|..:. :...:.|:.:  |||.|:.              |..|:              :|.:.
Zfish  1485 EHGSSSYGERRSYPDERQ--PPPTSLP--------------PSAPV--------------APPVE 1519

  Fly  1507 LFPSAANANDRTSDPMKASNLEMCVATSENRNTFSLDEVLLYPGRLNRPKRICIILRGPPGCGKS 1571
            ..|...||.|                            :|..|||.:||.||.:|:||.||.|||
Zfish  1520 KKPEIKNAED----------------------------ILKPPGRSSRPDRIVVIMRGLPGSGKS 1556

  Fly  1572 HVARLIKEKELEMGGANPRILSIDDYFLIENDYDEKCPKTGKKIPKKEILYEYDDTMEETYMQYL 1636
            |||:||::||:|.|||.||:|.:||||:.|.:..||.|.:||:|..|.:.|||:..||:||...:
Zfish  1557 HVAKLIRDKEVECGGAPPRVLGLDDYFMTEVEKIEKDPDSGKRIKTKVLEYEYEPEMEDTYRSSM 1621

  Fly  1637 IKSFKKTLSDNLYDFVIVDCNNNSLRTLNEFYCHAKDSNFVPYIVDLHCDLETCLGRNSHQRSVN 1701
            :|:|||||.|..:.|:|:|..|:.::..::|:..||...|..|:.::..|.:||..||.|.|::.
Zfish  1622 LKTFKKTLDDGFFPFIILDAINDKVKYFDQFWSAAKTKGFEVYLAEITTDQQTCAKRNIHGRTLK 1686

  Fly  1702 DIRVVLDNWCQTPTHYIKLDVSSLLEN-VVEMEDVEDMATDDNACADVGATVGESAALEDAAVEE 1765
            ||..:...|...|.|.::||:.|||:: .:|..::||....|...|:|
Zfish  1687 DISKLSGGWESAPPHMVRLDIRSLLQDAAIEDVEMEDFNPSDEPKAEV----------------- 1734

  Fly  1766 TDDSNSADASNYCGFL-KSKWERDTTEDNLARLDGT----KRLMQNRRTTSMADYLQLEDWKPPT 1825
            .:|.:..|    .|:: |||||.||:|..|.:|||.    || .::...:.|.|:|||.|.....
Zfish  1735 KNDDDETD----LGYVPKSKWEMDTSEAKLDKLDGLVGGGKR-KRDAGLSGMEDFLQLPDDYATR 1794

  Fly  1826 TSDNGKKRVRWADIEEKRSQKKMRAIGFVVGQTDWNRMMDPNA--GSRALNKTKF 1878
            .|:.|||||||||:||::...:.||||||||||||.::.|.:.  ..||||:||:
Zfish  1795 MSEPGKKRVRWADLEEQKDVDRKRAIGFVVGQTDWEKITDESGQIAQRALNRTKY 1849

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ZAP3	NP_001245607.1	AAA_33	1560..1702	CDD:463952	64/141 (45%)
ylpm1	XP_005170211.2	PHA03247	<421..826	CDD:223021	79/432 (18%)
		Pneumo_att_G	<628..813	CDD:114270	42/209 (20%)
		SF-CC1	1382..>1504	CDD:273721	15/126 (12%)
		AAA_33	1544..>1679	CDD:463952	60/134 (45%)