Protein Alignment CG15312 and NCAM2

DIOPT Version :10

• Sequence 1: NP_001245603.1
• Gene: CG15312 / 31940
• FlyBaseID: FBgn0030174
• Length: 464
• Species: Drosophila melanogaster
• Sequence 2: XP_011527877.1
• Gene: NCAM2 / 4685
• HGNCID: 7657
• Length: 874
• Species: Homo sapiens
• Alignment Length: 340
• Identity: 72/340 - (21%)
• Similarity: 108/340 - (31%)
• Gaps: 137/340 - (40%)

  Fly    19 FTQVLTVLSSTIKYNEYATDKGGNVSIPCIAQG----NIMWVK---------------------- 57
            |.||. |....|:.....|.:.|.|::.|.|:|    .|.|.:
Human   320 FLQVF-VQPHIIQLKNETTYENGQVTLVCDAEGEPIPEITWKRAVDGFTFTEGDKSLDGRIEVKG 383

  Fly    58 EHGNNSTIVQTGRVLVLRNVSTTDAGIYVCFAS----------------VPRPSTTAT---SATT 103
            :||::|        |.:::|..:|:|.|.|.|:                .|:..:..|   |...
Human   384 QHGSSS--------LHIKDVKLSDSGRYDCEAASRIGGHQKSMYLDIEYAPKFISNQTIYYSWEG 440

  Fly   104 SPQNL---------------QDK----------------------ETRPLEDEDDGQGESVSPKD 131
            :|.|:               :||                      |..|..|.|.|:....:...
Human   441 NPINISCDVKSNPPASIHWRRDKLVLPAKNTTNLKTYSTGRKMILEIAPTSDNDFGRYNCTATNH 505

  Fly   132 DQLKEAEMEEEVEYLAHQRTKLIVRTVPG--------PVSQLYFKASTILGFLIWRFNKTQS-GG 187
            ...:..      ||:      |.:..||.        .:||...|.|         |||..| ||
Human   506 IGTRFQ------EYI------LALADVPSSPYGVKIIELSQTTAKVS---------FNKPDSHGG 549

  Fly   188 YPVRSFTAEYRNVSYKTPPANASFEHAWSRMDPINIAFNVRQMEVY-RLAPNTTYEFRIWANNEL 251
            .|:..:..:.:.|:          ...|.    |..:..|:.|.|. .|.||||||.|:.|.|..
Human   550 VPIHHYQVDVKEVA----------SEIWK----IVRSHGVQTMVVLNNLEPNTTYEIRVAAVNGK 600

  Fly   252 GSGEVVTTNV-TTLP 265
            |.|:.....: .|||
Human   601 GQGDYSKIEIFQTLP 615

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG15312	NP_001245603.1	Ig	39..90	CDD:472250	16/76 (21%)
		Ig strand B	43..47	CDD:409358	1/3 (33%)
		Ig strand C	52..56	CDD:409358	1/3 (33%)
		Ig strand F	84..89	CDD:409358	2/4 (50%)
NCAM2	XP_011527877.1	IgI_1_NCAM-2	46..138	CDD:409452
		Ig strand A	46..51	CDD:409452
		Ig strand A'	54..58	CDD:409452
		Ig strand B	60..70	CDD:409452
		Ig strand C	74..80	CDD:409452
		Ig strand C'	83..85	CDD:409452
		Ig strand D	91..97	CDD:409452
		Ig strand E	99..107	CDD:409452
		Ig strand F	114..121	CDD:409452
		Ig strand G	126..137	CDD:409452
		Ig	142..218	CDD:472250
		Ig strand C	170..174	CDD:409353
		Ig strand E	193..197	CDD:409353
		IgI_1_MuSK	234..323	CDD:409562	1/2 (50%)
		Ig strand A	234..237	CDD:409562
		Ig strand A'	242..247	CDD:409562
		Ig strand B	253..260	CDD:409562
		Ig strand C	266..271	CDD:409562
		Ig strand C'	273..275	CDD:409562
		Ig strand D	282..285	CDD:409562
		Ig strand E	289..295	CDD:409562
		Ig strand F	302..309	CDD:409562
		Ig strand G	315..323	CDD:409562	1/2 (50%)
		IgI_NCAM-2	325..422	CDD:143278	20/104 (19%)
		Ig strand A	325..330	CDD:143278	1/4 (25%)
		Ig strand A'	334..338	CDD:143278	0/3 (0%)
		Ig strand B	342..350	CDD:143278	2/7 (29%)
		Ig strand C	356..362	CDD:143278	2/5 (40%)
		Ig strand C'	365..368	CDD:143278	0/2 (0%)
		Ig strand D	378..384	CDD:143278	0/5 (0%)
		Ig strand E	387..393	CDD:143278	2/13 (15%)
		Ig strand F	401..409	CDD:143278	4/7 (57%)
		Ig strand G	412..422	CDD:143278	0/9 (0%)
		Ig_3	426..504	CDD:464046	12/77 (16%)
		FN3	521..613	CDD:238020	30/114 (26%)
		fn3	619..703	CDD:394996