Protein Alignment CG15312 and NCAM1

DIOPT Version :10

• Sequence 1: NP_001245603.1
• Gene: CG15312 / 31940
• FlyBaseID: FBgn0030174
• Length: 464
• Species: Drosophila melanogaster
• Sequence 2: NP_001387553.1
• Gene: NCAM1 / 4684
• HGNCID: 7656
• Length: 1129
• Species: Homo sapiens
• Alignment Length: 562
• Identity: 92/562 - (16%)
• Similarity: 148/562 - (26%)
• Gaps: 283/562 - (50%)

  Fly    33 NEYATDKGGNVSIPCIAQG----NIMW-----------------------------VKEHGNNST 64
            |:.|.:....|::.|.|.|    :|.|                             |:.|...|:
Human   315 NQTAMELEEQVTLTCEASGDPIPSITWRTSTRNISSEEKASWTRPEKQETLDGHMVVRSHARVSS 379

  Fly    65 IVQTGRVLVLRNVSTTDAGIYVCFAS----------------VPR-------------------- 93
                   |.|:::..||||.|:|.||                .|:
Human   380 -------LTLKSIQYTDAGEYICTASNTIGQDSQSMYLEVQYAPKLQGPVAVYTWEGNQVNITCE 437

  Fly    94 ----PSTTAT---------SATTSPQNLQDK------ETRPLEDEDDGQ----------GESV-- 127
                ||.|.:         |:..|...:.:.      |..|..:.|.|.          .||:
Human   438 VFAYPSATISWFRDGQLLPSSNYSNIKIYNTPSASYLEVTPDSENDFGNYNCTAVNRIGQESLEF 502

  Fly   128 ---------SPKDDQLKEAEMEEEVEYLAHQRTKLIVRTVPGPVSQLYFKASTILGFLIWRFNKT 183
                     ||..||::......:|::...:.|
Human   503 ILVQADTPSSPSIDQVEPYSSTAQVQFDEPEAT-------------------------------- 535

  Fly   184 QSGGYPVRSFTAEYRNVSYKTPPANASFEHAW---------SRMDPINIAFNVRQMEVYRLAPNT 239
              ||.|:..:.||:|.|.          |..|         :.|:.|        :.:..|.|.|
Human   536 --GGVPILKYKAEWRAVG----------EEVWHSKWYDAKEASMEGI--------VTIVGLKPET 580

  Fly   240 TYEFRIWANNELGSGEVVTTNVTTLPETKE-----------ED----LIRLIKPD---------- 279
            ||..|:.|.|..|.||:...:.......:|           ||    .:.|||.|
Human   581 TYAVRLAALNGKGLGEISAASEFKTQPVREPSAPKLEGQMGEDGNSIKVNLIKQDDGGSPIRHYL 645

  Fly   280 ---------------------------LD-NFDPRIWIVA------------------------- 291
                                       || |.:..:::||
Human   646 VRYRALSSEWKPEIRLPSGSDHVMLKSLDWNAEYEVYVVAENQQGKSKAAHFVFRTSAQPTAIPA 710

  Fly   292 ---------VSIVLGTLVILAIGLCIVLSKECYQSAQMELQDGWDSIELIPNIILNPGFSESDGG 347
                     ...::|.|:::.:.|.:|:...||         ..:...|...|.:|     ..|.
Human   711 NGSPTSGLSTGAIVGILIVIFVLLLVVVDITCY---------FLNKCGLFMCIAVN-----LCGK 761

  Fly   348 PEPGGQGHGGSAGDQDAGEDDDDDVAMPFPRTIIFGQHHRTP 389
            ..||.:|.....|.....:|:..:     |...:..:..|||
Human   762 AGPGAKGKDMEEGKAAFSKDESKE-----PIVEVRTEEERTP 798

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG15312	NP_001245603.1	Ig	39..90	CDD:472250	17/83 (20%)
		Ig strand B	43..47	CDD:409358	1/3 (33%)
		Ig strand C	52..56	CDD:409358	2/32 (6%)
		Ig strand F	84..89	CDD:409358	2/4 (50%)
NCAM1	NP_001387553.1	IgI_1_NCAM-1	20..116	CDD:409451
		Ig strand A	20..25	CDD:409451
		Ig strand A'	28..32	CDD:409451
		Ig strand B	34..44	CDD:409451
		Ig strand C	50..56	CDD:409451
		Ig strand C'	59..61	CDD:409451
		Ig strand D	69..75	CDD:409451
		Ig strand E	77..85	CDD:409451
		Ig strand F	92..100	CDD:409451
		Ig strand G	104..115	CDD:409451
		IG_like	124..190	CDD:214653
		Ig strand B	135..139	CDD:409353
		Ig strand C	148..152	CDD:409353
		Ig strand E	172..176	CDD:409353
		Ig	211..307	CDD:472250
		Ig strand B	231..235	CDD:409353
		Ig strand C	244..248	CDD:409353
		Ig strand E	270..274	CDD:409353
		Ig strand F	284..289	CDD:409353
		Ig strand G	297..300	CDD:409353
		IgI_NCAM-1	306..412	CDD:143277	21/103 (20%)
		Ig strand A	306..311	CDD:143277
		Ig strand A'	315..319	CDD:143277	1/3 (33%)
		Ig strand B	324..332	CDD:143277	2/7 (29%)
		Ig strand C	338..344	CDD:143277	2/5 (40%)
		Ig strand C'	347..350	CDD:143277	0/2 (0%)
		Ig strand D	368..374	CDD:143277	1/5 (20%)
		Ig strand E	377..383	CDD:143277	2/12 (17%)
		Ig strand F	391..399	CDD:143277	4/7 (57%)
		Ig strand G	402..412	CDD:143277	0/9 (0%)
		IG_like	421..499	CDD:214653	9/77 (12%)
		Ig strand B	432..436	CDD:409353	0/3 (0%)
		Ig strand C	445..449	CDD:409353	1/3 (33%)
		Ig strand E	472..476	CDD:409353	0/3 (0%)
		Ig strand F	486..491	CDD:409353	0/4 (0%)
		fn3	511..598	CDD:394996	28/138 (20%)
		fn3	612..693	CDD:394996	11/80 (14%)
		PRK12323	<913..1108	CDD:481241