Protein Alignment Yp1 and PNLIPRP1

DIOPT Version :9

• Sequence 1: NP_001285071.1
• Gene: Yp1 / 31939
• FlyBaseID: FBgn0004045
• Length: 439
• Species: Drosophila melanogaster
• Sequence 2: NP_001290064.1
• Gene: PNLIPRP1 / 5407
• HGNCID: 9156
• Length: 467
• Species: Homo sapiens
• Alignment Length: 400
• Identity: 92/400 - (23%)
• Similarity: 152/400 - (38%)
• Gaps: 105/400 - (26%)

  Fly    98 KPNGDKTVAPLN------EMI-QRLKQKQNFGEDEVTIIVTGLPQTSET----VKKATRKLVQAY 151
            :|.|...:.||.      |.| .|.....|...:...|::...|.|.|.    :.:.||.::..:
Human    32 EPWGGTAIRPLKILPWSPEKIGTRFLLYTNENPNNFQILLLSDPSTIEASNFQMDRKTRFIIHGF 96

  Fly   152 MQRYNLQQQRQHGKNGNQDYQDQSNEQRKNQRTSSEEDYSEEV--KNAKTQSGDIIVID--LGSK 212
            :.:                               .:|.:..::  |..:.:..:.|.:|  .||:
Human    97 IDK-------------------------------GDESWVTDMCKKLFEVEEVNCICVDWKKGSQ 130

  Fly   213 LNTYERYAMLDIEKTGAKIGKWIVQMVNELDMPFDTIHLIGQNVGAHVAGAAAQEFTRLTGHKLR 277
            . ||.: |..::...||::.:.:..::.|...|...:||||.::||||||.|..:...|:
Human   131 A-TYTQ-AANNVRVVGAQVAQMLDILLTEYSYPPSKVHLIGHSLGAHVAGEAGSKTPGLS----- 188

  Fly   278 RVTGLDPSKIVAKSKNTLTGLARGDAEFVDAIHTSV------YGMGTPIRSGDVDFYPNGPAAGV 336
            |:|||||.:...:|......|...||:|||.|||..      .|.||..:.|.:||:||| ...:
Human   189 RITGLDPVEASFESTPEEVRLDPSDADFVDVIHTDAAPLIPFLGFGTNQQMGHLDFFPNG-GESM 252

  Fly   337 PGA-----SNVVEA--------------AMRATRYFAESVRPGNERSFPAVPANSLQQYKQNDGF 382
            ||.     |.:|:.              .:|:.:|:.||:.  |...|.|.|..|.:.::.:..|
Human   253 PGCKKNALSQIVDLDGIWAGTRDFVACNHLRSYKYYLESIL--NPDGFAAYPCTSYKSFESDKCF 315

  Fly   383 ----------GKRAYMGIDTAHDLEGDYILQVNPKSPF------------GRNAPAQKQSSYHGV 425
                      |..|........:.:..:.|.....|.|            ||.|..|.:.:..|
Human   316 PCPDQGCPQMGHYADKFAGRTSEEQQKFFLNTGEASNFARWRYGVSITLSGRTATGQIKVALFG- 379

  Fly   426 HQAWNTNQDS 435
             ...||:|.|
Human   380 -NKGNTHQYS 388

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Yp1	NP_001285071.1	Abhydrolase	183..406	CDD:304388	67/261 (26%)
PNLIPRP1	NP_001290064.1	Lipase	18..353	CDD:278576	82/361 (23%)
		Pancreat_lipase_like	52..349	CDD:238363	76/337 (23%)
		PLAT_PL	356..467	CDD:238857	8/34 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165145203
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_28N19
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11610
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	4	3.840