DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Yp1 and CG4582

DIOPT Version :9

Sequence 1:	NP_001285071.1	Gene:	Yp1 / 31939	FlyBaseID:	FBgn0004045	Length:	439	Species:	Drosophila melanogaster
Sequence 2:	NP_651403.1	Gene:	CG4582 / 43086	FlyBaseID:	FBgn0039344	Length:	432	Species:	Drosophila melanogaster

Alignment Length:	458	Identity:	117/458 - (25%)
Similarity:	174/458 - (37%)	Gaps:	119/458 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly    33 LKPSQWLSGSQLEAIPALDD--FTIERLENMNLERGAELLQQV-------YHL--SQIHHNVEPN 86
            |..|..:|..||   |.||:  ...|:||...|..|...::|.       |.|  |..||..
  Fly    24 LLSSGLMSPGQL---PILDEQHGRQEQLERHYLAHGPSSVEQQLLRLQPDYKLLYSAEHHTY--- 82

  Fly    87 YVPSGIQVYVPKPNGDKTVAPL--------NEMIQRL-------------------KQKQNFGED 124
               ..:...||:.|.::...||        ..:.|::                   :|.|.|..:
  Fly    83 ---FHLHTLVPQDNANRQTGPLKSEKESPHRRLFQQVVGNTLTAAFGLNVMNKGDQEQNQQFTSE 144

  Fly   125 EVTII-VTGLPQTSETVKKATRKLVQAYMQRYNLQQQRQHGKNGNQDYQDQSNEQRKNQRTSSEE 188
            .|.:. ...|.::..:....||.|:              ||..||:      |....|:...:..
  Fly   145 PVNLYDAASLRRSRFSPFNPTRILI--------------HGWLGNE------NANMYNELLPAYF 189

  Fly   189 DYSEEVKNAKTQSGDIIVIDLGSKLNTYERYAMLD-------IEKTGAKIGKWIVQMVNELDMPF 246
            |    ::|.   :.:|..:|.|       |.|:.|       ::..|..:.|::..:..|..|.|
  Fly   190 D----LRNG---NYNIFTVDWG-------RGAIADYITASYRVKPVGQVLAKFVDFLHQEAGMRF 240

  Fly   247 DTIHLIGQNVGAHVAGAAAQEFTRLTGHKLRRVTGLDPSK---IVAKSKNTLTGLARGDAEFVDA 308
            :.:.|:|.::||||||.|.:...  || :||.:..|||:.   ..||.|..||.   .||::|:.
  Fly   241 EDLQLVGFSMGAHVAGLAGKHLQ--TG-RLRMIRALDPALPFFRYAKPKERLTA---EDADYVEV 299

  Fly   309 IHTSV--YGMGTPIRSGDVDFYPNGPAAGVPGASNVVEAAMRATRYFAESVRPGNERSF--PAVP 369
            :||||  ||...|:  |.||||.|. .:..||......:..||...||||:.......|  ...|
  Fly   300 LHTSVGSYGFDRPV--GHVDFYANW-GSQQPGCFWHECSHWRAFMLFAESLARDQATGFLSQGCP 361

  Fly   370 ANSLQQ----YKQNDGFGKRAYMGIDTAH-------DLEGDYILQVNPKSPFGRNAPAQKQSSYH 423
            |...||    ::.....|....||.|.|:       ..:|.|..|.|.:.|:   ..||..||..
  Fly   362 AAEWQQLTRFHRCPKDTGVMQTMGGDLANVSAEFLAQRQGVYYFQTNDQPPY---VLAQNASSKR 423

  Fly   424 GVH 426
            ..|
  Fly   424 AAH 426

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Yp1	NP_001285071.1	Abhydrolase	183..406	CDD:304388	71/247 (29%)
CG4582	NP_651403.1	Pancreat_lipase_like	138..409	CDD:238363	84/313 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45445895
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_28N19
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11610
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.840