| Sequence 1: | NP_511103.1 | Gene: | Yp1 / 31939 | FlyBaseID: | FBgn0004045 | Length: | 439 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_000228.1 | Gene: | LPL / 4023 | HGNCID: | 6677 | Length: | 475 | Species: | Homo sapiens |
| Alignment Length: | 173 | Identity: | 56/173 - (32%) |
|---|---|---|---|
| Similarity: | 86/173 - (49%) | Gaps: | 19/173 - (10%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 203 DIIVIDLGSKLNTYERYAMLDIEKTGAKIGKWIVQMVNELDMPFDTIHLIGQNVGAHVAGAAAQE 267
Fly 268 FTRLTGHKLRRVTGLDPSKIVAKSKNTLTGLARGDAEFVDAIHTSVYGMGTPIRS-------GDV 325
Fly 326 DFYPNG----PAAGVPGASNVVEAAMRATRYFAESVRPGNERS 364 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| Yp1 | NP_511103.1 | Lipase | 129..410 | CDD:395099 | 56/173 (32%) |
| LPL | NP_000228.1 | Interaction with GPIHBP1. /evidence=ECO:0000269|PubMed:30559189 | 32..53 | ||
| lipo_lipase | 33..473 | CDD:132274 | 56/173 (32%) | ||
| Essential for determining substrate specificity. /evidence=ECO:0000269|PubMed:7592706 | 243..266 | 5/24 (21%) | |||
| Important for interaction with lipoprotein particles. /evidence=ECO:0000269|PubMed:27929370 | 417..421 | ||||
| Important for heparin binding. /evidence=ECO:0000269|PubMed:11342582 | 430..434 | ||||
| Interaction with GPIHBP1. /evidence=ECO:0000269|PubMed:26725083, ECO:0000269|PubMed:30559189 | 443..467 | ||||
| Blue background indicates that the domain is not in the aligned region. | |||||