Protein Alignment Yp1 and LIPH

DIOPT Version :10

• Sequence 1: NP_511103.1
• Gene: Yp1 / 31939
• FlyBaseID: FBgn0004045
• Length: 439
• Species: Drosophila melanogaster
• Sequence 2: NP_640341.1
• Gene: LIPH / 200879
• HGNCID: 18483
• Length: 451
• Species: Homo sapiens
• Alignment Length: 254
• Identity: 67/254 - (26%)
• Similarity: 103/254 - (40%)
• Gaps: 38/254 - (14%)

  Fly   203 DIIVIDLGSKLNT-YERYAMLDIEKTGAKIGKWIVQMVNELDMPFDTIHLIGQNVGAHVAGAAAQ 266
            :::|:|......| ...:|.....|....:.::|.||:.| ....|.|::||.::|||::|...:
Human   102 NVVVVDWNRGATTLIYTHASSKTRKVAMVLKEFIDQMLAE-GASLDDIYMIGVSLGAHISGFVGE 165

  Fly   267 EFTRLTGHKLRRVTGLDPSKIVAKSKNTLTGLARGDAEFVDAIHTSVYGMGTPIRSGDVDFYPNG 331
            .:....|    |:|||||:..:...|.....|...||:|||.||:....:|.....|::||||||
Human   166 MYDGWLG----RITGLDPAGPLFNGKPHQDRLDPSDAQFVDVIHSDTDALGYKEPLGNIDFYPNG 226

  Fly   332 PAAGVPGASNVVEAA--------MRATRYFAESVRPGNERSFPAVPANSLQQYKQNDGFGKRAYM 388
             ....||....:...        .|:...:..|:|  ...:..|.|.:|.|.|:.    ||....
Human   227 -GLDQPGCPKTILGGFQYFKCDHQRSVYLYLSSLR--ESCTITAYPCDSYQDYRN----GKCVSC 284

  Fly   389 GIDTAHD--LEGDYILQVNPKSPF-GRNAPAQK-------QSSYHGVHQ-----AWNTN 432
            |......  |.|.|  ..|.|... |::.|..|       :|.:...|.     .||.|
Human   285 GTSQKESCPLLGYY--ADNWKDHLRGKDPPMTKAFFDTAEESPFCMYHYFVDIITWNKN 341

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Yp1	NP_511103.1	Lipase	129..410	CDD:395099	59/217 (27%)
LIPH	NP_640341.1	Pancreat_lipase_like	39..303	CDD:238363	58/214 (27%)