DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Yp1 and Pnliprp1

DIOPT Version :9

Sequence 1:	NP_001285071.1	Gene:	Yp1 / 31939	FlyBaseID:	FBgn0004045	Length:	439	Species:	Drosophila melanogaster
Sequence 2:	NP_061362.1	Gene:	Pnliprp1 / 18946	MGIID:	97723	Length:	473	Species:	Mus musculus

Alignment Length:	281	Identity:	73/281 - (25%)
Similarity:	115/281 - (40%)	Gaps:	72/281 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly   134 PQTSET----VKKATRKLVQAYMQRYNLQQQRQHGKNGNQDYQDQSNEQRKNQRTSSEEDYSEEV 194
            |.|.|.    |.:.||.::..::.:                               .||::..::
Mouse    75 PSTIEASNFQVARKTRFIIHGFIDK-------------------------------GEENWVVDM 108

  Fly   195 -KNA-KTQSGDIIVID--LGSKLNTYERYAMLDIEKTGAKIGKWIVQMVNELDMPFDTIHLIGQN 255
             ||. :.:..:.|.:|  .||: .||.: |..::...||::.:.|..:|...:.....:||||.:
Mouse   109 CKNMFQVEEVNCICVDWKRGSQ-TTYTQ-AANNVRVVGAQVAQMIDILVRNFNYSASKVHLIGHS 171

  Fly   256 VGAHVAGAAAQEFTRLTGHKLRRVTGLDPSKIVAKSKNTLTGLARGDAEFVDAIHTSV------Y 314
            :||||||.|.   :|..|  |.|:|||||.:...:.......|...||:|||.|||..      .
Mouse   172 LGAHVAGEAG---SRTPG--LGRITGLDPVEANFEGTPEEVRLDPSDADFVDVIHTDAAPLIPFL 231

  Fly   315 GMGTPIRSGDVDFYPNG----PAAGVPGASNVVEA--------------AMRATRYFAESVRPGN 361
            |.||....|..||:|||    |.......|.:|:.              .:|:.:|:.||:.  |
Mouse   232 GFGTNQMVGHFDFFPNGGQYMPGCKKNALSQIVDIDGIWSGTRDFVACNHLRSYKYYLESIL--N 294

  Fly   362 ERSFPAVPANSLQQYKQNDGF 382
            ...|.|.|..|.:.::.|..|
Mouse   295 PDGFAAYPCASYRDFESNKCF 315

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Yp1	NP_001285071.1	Abhydrolase	183..406	CDD:304388	67/228 (29%)
Pnliprp1	NP_061362.1	Lipase	18..353	CDD:278576	73/281 (26%)
		Pancreat_lipase_like	52..349	CDD:238363	73/281 (26%)
		PLAT_PL	356..467	CDD:238857
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167835293
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_28N19
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11610
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.840