DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Yp2 and LOC100331214

DIOPT Version :9

Sequence 1:	NP_001285070.1	Gene:	Yp2 / 31938	FlyBaseID:	FBgn0005391	Length:	442	Species:	Drosophila melanogaster
Sequence 2:	XP_002666287.3	Gene:	LOC100331214 / 100331214	-ID:	-	Length:	501	Species:	Danio rerio

Alignment Length:	361	Identity:	91/361 - (25%)
Similarity:	128/361 - (35%)	Gaps:	125/361 - (34%)

- Green bases have known domain annotations that are detailed below.

  Fly    67 SLEEGATLLDKLYHLSQFNHVFKPDYTPEPSQIRGYIVGERGQKIEFNLNTLVEKVKRQQKFG-- 129
            :||||..|          |.||  |:..|                  :|..|.:..|...||.
Zfish    24 ALEEGNVL----------NGVF--DHFLE------------------DLRDLSDVKKLNVKFSLR 58

  Fly   130 -----DDEVTIFIQGLPETNTQ---------------------VQKATRKLVQAYQQRYNLQPYE 168
                 ||:|...::|..||.:.                     .:....|||.|.
Zfish    59 NPSQPDDDVCYIVRGKAETLSSCNFNHTSKTILVIHGWTVSGLFESWVEKLVAAL---------- 113

  Fly   169 TTDYSNEEQSQRSSSEEQQTQRRKQNGEQDDTKTGDLIVIQLGNAIEDFEQYATLNIERLGEIIG 233
               |:.|                         |..::||:...:..:|....|..|.:.:|..||
Zfish   114 ---YNRE-------------------------KDANVIVVDWLDTAQDHYVVAAQNTKMVGREIG 150

  Fly   234 NRLVELTNTVNVPQEIIHLIGSGPAAHVAGVAGRQFTRQTGHKLRRITALDP-------TKIYGK 291
            ..:..:..|.|||.|.:||||....|||||.||    ..|.:|:.|||.|||       ...:|:
Zfish   151 LFIDWIEETSNVPLENLHLIGYSLGAHVAGFAG----SHTTNKIGRITGLDPAGPDFEGVHAHGR 211

  Fly   292 PEERLTGLARGDADFVDAIHTSAYG-----MGTSQRLANVDFFPNGPSTGVPGADNVVEATMRAT 351
                   |:..||.|||.:||...|     :|..|.:.:||.:|||.|. .||. |:..|..:..
Zfish   212 -------LSPDDAHFVDVLHTFTRGSLGLSIGIEQPVGHVDIYPNGGSF-QPGC-NLRGALEKMA 267

  Fly   352 RY--FA--ESVRPGNERNFPSVAASSYQEYKQNKGY 383
            .|  ||  .::|..:||:......|...|....:.|
Zfish   268 SYGIFAINNAIRCEHERSIHLFIDSLLNEEAAGRAY 303

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Yp2	NP_001285070.1	Lipase	97..411	CDD:278576	81/331 (24%)
Yp2	NP_001285070.1	Abhydrolase	<221..407	CDD:304388	60/179 (34%)
LOC100331214	XP_002666287.3	lipo_lipase	47..487	CDD:132274	79/308 (26%)
		Pancreat_lipase_like	51..347	CDD:238363	78/304 (26%)
		PLAT_LPL	355..485	CDD:238856
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_28N19
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11610
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.910