DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cht6 and Ctbs

DIOPT Version :9

Sequence 1:	NP_001245598.1	Gene:	Cht6 / 31935	FlyBaseID:	FBgn0263132	Length:	4611	Species:	Drosophila melanogaster
Sequence 2:	NP_001280601.1	Gene:	Ctbs / 74245	MGIID:	1921495	Length:	366	Species:	Mus musculus

Alignment Length:	330	Identity:	78/330 - (23%)
Similarity:	124/330 - (37%)	Gaps:	71/330 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    94 GLKTYN----KQLKTMIAIGGWNE-----ASSRFSPLVASNE----------RRQQFIKNILKFL 139
            |.||:.    .|:.|:.|.|.::.     |.|:.:.:|...:          .|..:|...:...
Mouse    50 GQKTWKSYDWSQITTVAAFGKYDPELMCYAHSKGARVVLKGDISLKNIIDPTFRASWIAQKVDLA 114

  Fly   140 RQNHFDGIDLDWEYPAHREGGKSRDRDNYAQFVQELRAEFEREAEKTGRTRLLLTMAVPAGIEYI 204
            :..:.|||::|.|...:   ..|.:.:.....|:|....|:||.|.:     .:|..|....:.|
Mouse   115 KAQYMDGINIDIEQEVN---CSSPEYEALTALVKETTESFQREIEGS-----QVTFDVAWSPKRI 171

  Fly   205 DKG-YDVPKLNKYLDWFNVLTYDFHSS--HEPSVNHHAPLYSLEEDSEYNYDAELNIDYSIKYYL 266
            ||. |:...:....|:..|::||..|.  .|.....:||         ||......||     |:
Mouse   172 DKRCYNYTGIADACDFLFVMSYDEQSQIWSECIAAANAP---------YNQTLTGYID-----YI 222

  Fly   267 KAGADRDKLVLGIPTYGRSYTLINEESTELGAPAEGPGEQGDATREKGYLAYYEICQTLKDDPEW 331
            |.|....|||:|:|.||..|..:|....::....:.|......:...|:...|::
Mouse   223 KMGISPKKLVMGVPWYGYDYICLNLSKDDICTITKVPFRGAPCSDAAGHQVPYKV---------- 277

  Fly   332 TVVQPNANVMGP----------YAYR----RNQWVGYDDEAIVRKKAEYVVAQGLGGIMFW---A 379
            .:.|.|.:|.|.          |.|:    |...|.||:...:..||.||...||.||..|   .
Mouse   278 IMKQVNGSVSGSQWNKDQQAPYYNYKDPAGRFHQVWYDNPQSISLKAAYVKNYGLRGIGMWNANC 342

  Fly   380 IDNDD 384
            :|..|
Mouse   343 LDYSD 347

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cht6	NP_001245598.1	Glyco_18	31..383	CDD:214753	77/327 (24%)
		GH18_chitolectin_chitotriosidase	32..404	CDD:119351	78/330 (24%)
		CBM_14	506..562	CDD:279884
		Oxidored_q2	<2691..2750	CDD:294335
		CBM_14	4554..4609	CDD:279884
Ctbs	NP_001280601.1	GH18_chitobiase	24..362	CDD:119354	78/330 (24%)
Ctbs	NP_001280601.1	Glyco_18	<99..342	CDD:214753	66/274 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3325
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810