DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Cht6 and XB5763442

DIOPT Version :9

Sequence 1:	NP_001245598.1	Gene:	Cht6 / 31935	FlyBaseID:	FBgn0263132	Length:	4611	Species:	Drosophila melanogaster
Sequence 2:	XP_031751817.1	Gene:	XB5763442 / 548945	XenbaseID:	XB-GENE-5763443	Length:	486	Species:	Xenopus tropicalis

Alignment Length:	549	Identity:	186/549 - (33%)
Similarity:	285/549 - (51%)	Gaps:	74/549 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    13 LFLLCALAYCINEASSEGRVVCYYTNWSVYRPGTAKFNPQNINPYLCTHLVYAFGGFTKDNQMKP 77
            |||...|...: :..|..::|||:|||:.|.||.|::.|.:::|.:||||:|||...| :|::..
Frog     6 LFLGITLLLHV-QLGSSFKLVCYFTNWAQYYPGVAQYMPDDVDPCMCTHLIYAFATMT-NNEIAI 68

  Fly    78 FDKYQDIEQGGYAKFTGLKTYNKQLKTMIAIGGWNEASSRFSPLVASNERRQQFIKNILKFLRQN 142
            |:..   :...||.|..||.||.:|||::::||||..:|.|:.:|:|.:.||.||.:::.|||:.
Frog    69 FEPN---DPAFYASFNALKNYNSELKTLLSVGGWNYGTSGFNNMVSSPQNRQTFINSVITFLRKY 130

  Fly   143 HFDGIDLDWEYPAHRE-GGKSRDRDNYAQFVQELRAEFEREAEKTGRTRLLLTMAVPAGIEYIDK 206
            .|||:|:|||||...: |.....::.|:..:||:...|.:||.::...|||::.||.||:..|:.
Frog   131 GFDGLDIDWEYPGDSDRGSPPETKEQYSILLQEMYNAFVQEASQSNLPRLLISAAVSAGMPTIEA 195

  Fly   207 GYDVPKLNKYLDWFNVLTYDFHSSHEPSVNHHAPLYSLEED-SEYNYDAELNIDYSIKYYLKAGA 270
            ||.:|:|::|||..||:|||...|.|......:|||....| ..|.|   .|:||::.|:...||
Frog   196 GYQIPQLSQYLDLINVMTYDLRGSWEGFTGEDSPLYQGPADQGGYIY---FNVDYAMNYWKNNGA 257

  Fly   271 DRDKLVLGIPTYGRSYTLINEESTELGAPAEGPGEQGDATREKGYLAYYEICQTLKDDPEWTVVQ 335
            ..:||::|.|.|||::||.:..:..||||..|.|.....|:|.|::||:|||..||...  |||.
Frog   258 APEKLMVGFPAYGRTFTLSDPSNNGLGAPTSGGGPAAPYTQESGFMAYFEICNFLKQGA--TVVW 320

  Fly   336 PNANVMGPYAYRRNQWVGYDDEAIVRKKAEYVVAQGLGGIMFWAIDNDDFRG-TCNGKPYPLIEA 399
             |:....||||:.::|:|||:|...:.|||:::....||.|.||:..|||.| .|....|||:..
Frog   321 -NSPQAVPYAYKGSEWIGYDNEKSFQIKAEWLMKNNFGGAMVWALPLDDFSGHFCGQGNYPLMNT 384

  Fly   400 AKEAMVEALGLGINEVAKPSGPQKPSRSRSRDNASNRNRLNGKTEAPLSSRRPSATRRPAVSSTQ 464
            .|..      |||      |.|                          :.:.|:.|..|   :|.
Frog   385 LKST------LGI------SFP--------------------------NCKAPTVTVAP---NTA 408

  Fly   465 APPPSTTFKLTEAEGSSLYIGGRASTTPPPPTTPDPGSDFKC--EEEGFFQHPRDCKKYYWCLDS 527
            ||..:.|.......|.| ..||.||.:        ..|.| |  :..|.:..|.:...::.||:.
Frog   409 APTEAATTASASGSGGS-GSGGSASGS--------SSSGF-CVGKSNGLYPDPTNKSGFFNCLNG 463

  Fly   528 GPSGLGIVAHMFTCPSGLYFNPAADSCDF 556
                   :.:...|.:.|.|:.:...|::
Frog   464 -------ITYQQACQTSLVFDASCSCCNW 485

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cht6	NP_001245598.1	Glyco_18	31..383	CDD:214753	143/353 (41%)
		GH18_chitolectin_chitotriosidase	32..404	CDD:119351	152/374 (41%)
		CBM_14	506..562	CDD:279884	9/53 (17%)
		Oxidored_q2	<2691..2750	CDD:294335
		CBM_14	4554..4609	CDD:279884
XB5763442	XP_031751817.1	None
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D264489at33208
OrthoFinder	1	1.000	-	-		FOG0000107
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.920